항GT1강글리오시드항체와 연관된 길랭-바레증후군
Guillain-Barré Syndrome With Antibody to Ganglioside GT1a
2
조회
0
다운로드
3
인용
0
참고문헌
키워드
초록
The presence of serum antibodies to various gangliosides, such as anti-GQ1b, is closely related to the clinical features of Guillain‐Barré syndrome. However, the phenotype associated with anti-GT1a IgG has not yet been determined, although it has been detected in some cases of the pharyngeal-cervical‐brachial variant. We report herein two patients harboring anti-GT1a IgG who both presented with profound dyspnea, dysphagia, and quadriparesis. The findings of this report suggest that the anti-GT1a antibody specifies a clinical feature of oropharyngeal palsy.
Abstract
The presence of serum antibodies to various gangliosides, such as anti-GQ1b, is closely related to the clinical features of Guillain‐Barré syndrome. However, the phenotype associated with anti-GT1a IgG has not yet been determined, although it has been detected in some cases of the pharyngeal-cervical‐brachial variant. We report herein two patients harboring anti-GT1a IgG who both presented with profound dyspnea, dysphagia, and quadriparesis. The findings of this report suggest that the anti-GT1a antibody specifies a clinical feature of oropharyngeal palsy.
참고문헌 (9)
- Ropper AH, "Guillain- Barre syndrome", pp.1~369 (1991)
- 김종국, "항-GQ1b 항체증후군; Miller Fisher 증후군의 다른 이름인가, 새로운 증후군의 출현인가?", 대한신경과학회지, 27(4), pp.307~312 (2009), 대한신경과학회
- Koga M, "Anti-GT1a IgG in Guillain-Barre syndrome", J Neurol Neurosurg Psychiatry, 72, pp.767~771 (2002)
- Nagashima T, "Clinical correlates of serum anti-GT1a IgG antibodies", J Neurol Sci, 219, pp.139~145 (2004)
- Koga M, "Is IgG anti-GT1a antibody associated with pharyngeal-cervical-brachial weakness or oropharyngeal palsy in Guillain-Barre syndrome?", J Neuroimmunol, 86, pp.74~79 (1998)
- Kaida K, "GM1", GalNAc-GD1a complex: a target for pure motor Guillain-Barre syndrome, 2008, pp.71, 1683~1690
- Nagashima T, "Continuous spectrum of pharyngeal-cervical-brachial variant of Guillain-Barre syndrome", Arch Neurol, 64, pp.1519~1523 (2007)
- Willison HJ, "Peripheral neuropathies and anti-glycolipid antibodies", Brain, 125, pp.2591~2625 (2002)
- Ilyas AA, "Antibodies to GT1a ganglioside in patients with Guillain-Barre syndrome", J Neuroimmunol, 82, pp.160~167 (1998)