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난소선암에 동반된 신생물딸림 괴사근병증

Paraneoplastic Necrotizing Myopathy Associated With Ovarian Adenocarcinoma

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초록

We describe here a case of female patient who presented with mild proximal weakness, myalgia, and markedly elevatedCPK, which could be ascribed to paraneoplastic necrotizing myopathy in association with ovarian adenocarcinoma. Ahistologic examination of the vastus lateralis muscle showed necrosis of muscle fibers without inflammatory cellinfiltration. Her neurologic symptoms improved following tumor resection and systemic chemotherapy. Paraneoplasticnecrotizing myopathy may be a presenting manifestation of malignancy, and early recognition and prompt treatment arecrucial for the clinical improvement.

Abstract

We describe here a case of female patient who presented with mild proximal weakness, myalgia, and markedly elevatedCPK, which could be ascribed to paraneoplastic necrotizing myopathy in association with ovarian adenocarcinoma. Ahistologic examination of the vastus lateralis muscle showed necrosis of muscle fibers without inflammatory cellinfiltration. Her neurologic symptoms improved following tumor resection and systemic chemotherapy. Paraneoplasticnecrotizing myopathy may be a presenting manifestation of malignancy, and early recognition and prompt treatment arecrucial for the clinical improvement.

참고문헌 (10)

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