스테로이드 치료에 반응을 보인 재발성 LGI1 항체연관변연계뇌염
Steroid Responsive Recurrent Limbic Encephalitis Associated With LGI1 Antibodies
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초록
Limbic encephalitis (LE) is characterized by short-term memory loss, disorientation, agitation, seizures, and histologicalevidence of mesial temporal lobe inflammation. Leucine-rich, glioma inactivated 1 (LGI1) is the autoantigen associatedwith limbic encephalitis that was previously attributed to voltage-gated potassium channels. We report herein a54-year-old female with LGI1-related limbic encephalitis who presented with recurrent episodes of episodic memoryimpairment, depressive mood, and phantosmia. Her symptoms dramatically improved with steroid therapy.
Abstract
Limbic encephalitis (LE) is characterized by short-term memory loss, disorientation, agitation, seizures, and histologicalevidence of mesial temporal lobe inflammation. Leucine-rich, glioma inactivated 1 (LGI1) is the autoantigen associatedwith limbic encephalitis that was previously attributed to voltage-gated potassium channels. We report herein a54-year-old female with LGI1-related limbic encephalitis who presented with recurrent episodes of episodic memoryimpairment, depressive mood, and phantosmia. Her symptoms dramatically improved with steroid therapy.
참고문헌 (10)
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