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Gastrointestinal Dysfunctions in Parkinson’s Disease
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초록
Gastrointestinal symptoms are a frequent but usually underreported constituent of the clinical spectrum of Parkinson’s disease (PD), and they contribute significantly to the disease-related morbidity and mortality. Virtually all parts of the gastrointestinal tract can be affected, even in the premotor stage. Weight loss, salivary excess, dysphagia, nausea/gastroparesis, constipation, and anorectal dysfunction can all occur. Gastrointestinal symptoms may result from the involvement of either the central or enteric nervous system in the disease process, or be a side effect of antiparkinsonian medications. Awareness of the various gastrointestinal manifestations of PD can facilitate the prompt recognition of and effective therapeutic intervention for these potentially distressing symptoms.
Abstract
Gastrointestinal symptoms are a frequent but usually underreported constituent of the clinical spectrum of Parkinson’s disease (PD), and they contribute significantly to the disease-related morbidity and mortality. Virtually all parts of the gastrointestinal tract can be affected, even in the premotor stage. Weight loss, salivary excess, dysphagia, nausea/gastroparesis, constipation, and anorectal dysfunction can all occur. Gastrointestinal symptoms may result from the involvement of either the central or enteric nervous system in the disease process, or be a side effect of antiparkinsonian medications. Awareness of the various gastrointestinal manifestations of PD can facilitate the prompt recognition of and effective therapeutic intervention for these potentially distressing symptoms.
참고문헌 (54)
- Makaroff L, "Gastrointestinal disorders in Parkinson's disease: prevalence and health outcomes in a US claims database", J Parkinsons Dis, 1, pp.65~74 (2011)
- Pfeiffer RF, "Gastrointestinal dysfunction in Parkinson’s disease", Parkinsonism Relat Disord, 17, pp.10~15 (2011)
- Cloud LJ, "Gastrointestinal features of Parkinson’s disease", Curr Neurol Neurosci Rep, 11, pp.379~384 (2011)
- Cersosimo MG, "Gastrointestinal manifestations in Parkinson's disease: prevalence and occurrence before motor symptoms", J Neurol, 260, pp.1332~1338 (2013)
- Sung HY, "The frequency and severity of gastrointestinal symptoms in patients with early Parkinson's disease", J Mov Disord, 7, pp.7~12 (2014)
- Abbott RA, "Diet, body size and micronutrient status in Parkinson’s disease", Eur J Clin Nutr, 46, pp.879~884 (1992)
- Durrieu G, "Parkinson’s disease and weight loss: a study with anthropometric and nutritional assessment", Clin Auton Res, 2, pp.153~157 (1992)
- Bachmann CG, "Body weight in patients with Parkinson's disease", Mov Disord, 21, pp.1824~1830 (2006)
- Eadie MJ, "Alimentary disorder in parkinsonism", Australas Ann Med, 14, pp.13~22 (1965)
- Edwards LL, "Gastrointestinal symptoms in Parkinson’s disease", Mov Disord, 6, pp.151~156 (1991)
- Tumilasci OR, "Quantitative study of salivary secretion in Parkinson’s disease", Mov Disord, 21, pp.660~667 (2006)
- Nóbrega AC, "Is drooling secondary to a swallowing disorder in patients with Parkinson’s disease?", Parkinsonism Relat Disord, 14, pp.243~245 (2008)
- Arbouw ME, "Glycopyrrolate for sialorrhea in Parkinson disease: a randomized, double-blind, crossover trial", Neurology, 74, pp.1203~1207 (2010)
- Ondo WG, "A double-blind placebo-controlled trial of botulinum toxin B for sialorrhea in Parkinson’s disease", Neurology, 62, pp.37~40 (2004)
- Lagalla G, "Botulinum toxin type A for drooling in Parkinson’s disease: a double-blind, randomized, placebo-controlled study", Mov Disord, 21, pp.704~707 (2006)
- Clarke CE, "Referral criteria for speech and language therapy assessment of dysphagia caused by idiopathic Parkinson’s disease", Acta Neurol Scand, 97, pp.27~35 (1998)
- Leopold NA, "Prepharyngeal dysphagia in Parkinson’s disease", Dysphagia, 11, pp.14~22 (1996)
- Bushmann M, "Swallowing abnormalities and their response to treatment in Parkinson’s disease", Neurology, 39, pp.1309~1314 (1989)
- Leopold NA, "Pharyngo-esophageal dysphagia in Parkinson’s disease", Dysphagia, 12, pp.11~18 (1997)
- Fuh JL, "Swallowing difficulty in Parkinson’s disease", Clin Neurol Neurosurg, 99, pp.106~112 (1997)
- Potulska A, "Swallowing disorders in Parkinson’s disease", Parkinsonism Relat Disord, 9, pp.349~353 (2003)
- Bird MR, "Asymptomatic swallowing disorders in elderly patients with Parkinson’s disease: a description of findings on clinical examination and videofluoroscopy in sixteen patients", Age Aging, 23, pp.251~254 (1994)
- Thomas M, "Dysphagia, a reversible cause not to be forgotten", Postgrad Med J, 71, pp.94~95 (1995)
- Sung HY, "The prevalence and patterns of pharyngoesophageal dysmotility in patients with early stage Parkinson's disease", Mov Disord, 25, pp.2361~2368 (2010)
- McCallum SL, "The National Dysphagia Diet: implementation at a regional rehabilitation center and hospital system", J Am Diet Assoc, 103, pp.381~384 (2003)
- Born LJ, "Cricopharyngeal dysfunction in Parkinson’s disease: role in dysphagia and response to myotomy", Mov Disord, 11, pp.53~58 (1996)
- Truong DD, "Botulinum toxin: clinical use", Parkinsonism Relat Disord, 12, pp.331~355 (2006)
- Edwards LL, "Gastrointestinal symptoms in Parkinson’s disease", Mov Disord, 6, pp.151~156 (1991)
- Hardoff R, "Gastric emptying time and gastric motility in patients with Parkinson's disease", Mov Disord, 16, pp.1041~1047 (2001)
- Lertxundi U, "Domperidone in Parkinson's disease: a perilous arrhythmogenic or the gold standard?", Curr Drug Saf, 8, pp.63~68 (2013)
- Gabrielli M, "Prevalence of small intestinal bacterial overgrowth in Parkinson's disease", Mov Disord, 26, pp.889~892 (2011)
- Fasano A, "The role of small intestinal bacterial overgrowth in Parkinson's disease", Mov Disord, 28, pp.1241~1249 (2013)
- Siddiqui MF, "Autonomic dysfunction in Parkinson’s disease: a comprehensive symptom survey", Parkinsonism Relat Disord, 8, pp.277~284 (2002)
- Kaye J, "Excess burden of constipation in Parkinson’s disease: a pilot study", Mov Disord, 21, pp.1270~1273 (2006)
- Stocchi F, "Anorectal function in multiple system atrophy and Parkinson’s disease", Mov Disord, 15, pp.71~76 (2000)
- Jost WH, "Constipation in Parkinson’s disease", Klin Wochenschr, 69, pp.906~909 (1991)
- Sakakibara R, "Colonic transit time and rectoanal videomanometry in Parkinson’s disease", J Neurol Neurosurg Psychiatry, 74, pp.268~272 (2003)
- Edwards LL, "Characterization of swallowing and defecation in Parkinson’s disease", Am J Gastroenterol, 89, pp.15~25 (1994)
- Kim JS, "Anorectal dysfunctions in Parkinson's disease", J Neurol Sci, 310, pp.144~151 (2011)
- 성혜영, "Anorectal Manometric Dysfunctions in Newly Diagnosed, Early-Stage Parkinson’s Disease", Journal of Clinical Neurology, 8(3), pp.184~189 (2012), 대한신경과학회
- Mathers SE, "Constipation and paradoxical puborectalis contraction in anismus and Parkinson’s disease: a dystonic phenomenon?", J Neurol Neurosurg Psychiatry, 51, pp.1503~1507 (1988)
- Mathers SE, "Anal sphincter dysfunction in Parkinson’s disease", Arch Neurol, 46, pp.1061~1064 (1989)
- Ashraf W, "Constipation in Parkinson’s disease: objective assessment and response to psyllium", Mov Disord, 12, pp.946~951 (1997)
- Zangaglia R, "Macrogol for the treatment of constipation in Parkinson’s disease. A randomized placebo-controlled study", Mov Disord, 22, pp.1239~1244 (2007)
- Camilleri M, "A placebo-controlled trial of prucalopride for severe chronic constipation", N Engl J Med, 358, pp.2344~2354 (2008)
- Albanese A, "Severe constipation in Parkinson’s disease relieved by botulinum toxin", Mov Disord, 12, pp.764~766 (1997)
- Ueki A, "Life style risks of Parkinson’s disease: association between decreased water intake and constipation", J Neurol, 251, pp.vii18~vii23 (2004)
- Kaye J, "Excess burden of constipation in Parkinson’s disease: a pilot study", Mov Disord, 21, pp.1270~1273 (2006)
- Ashraf W, "Constipation in Parkinson’s disease: objective assessment and response to psyllium", Mov Disord, 12, pp.946~951 (1997)
- Siddiqui MF, "Autonomic dysfunction in Parkinson’s disease: a comprehensive symptom survey", Parkinsonism Relat Disord, 8, pp.277~284 (2002)
- Abbott RD, "Frequency of bowel movements and the future risk of Parkinson’s disease", Neurology, 57, pp.456~462 (2001)
- Derkinderen P, "Parkinson disease: the enteric nervous system spills its guts", Neurology, 77, pp.1761~1767 (2011)
- Wakabayashi K, "Parkinson’s disease: the presence of Lewy bodies in Auerbach’s and Meissner’s plexuses", Acta Neuropathol, 76, pp.217~221 (1988)
- Visanji NP, "Alimentary, my dear Watson? The challenges of enteric α-synuclein as a Parkinson's disease biomarker", Mov Disord, 29, pp.444~450 (2014)
