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Olanzapine으로 치료 중인 조현병 환자에서 발생한 저나트륨혈증유발발작

Hyponatremia-induced Seizures in Schizophrenic Patient Treated with Olanzapine

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주제분류신경과학

초록

Severe hyponatremia (serum sodium concentration <120 mEq/L) is a well-known etiology of acute symptomatic seizure. Severe hyponatremia may occur as a rare but clinically important adverse reaction of psychotrophic drugs. Among them, patients with psychogenic polydipsia have especially higher risk of severe hyponatremia. We present a schizophrenic patient with polydipsia who developed severe hyponatremia and symptomatic seizures while receiving olanzapine treatment.

Abstract

Severe hyponatremia (serum sodium concentration <120 mEq/L) is a well-known etiology of acute symptomatic seizure. Severe hyponatremia may occur as a rare but clinically important adverse reaction of psychotrophic drugs. Among them, patients with psychogenic polydipsia have especially higher risk of severe hyponatremia. We present a schizophrenic patient with polydipsia who developed severe hyponatremia and symptomatic seizures while receiving olanzapine treatment.

참고문헌 (10)

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  10. 이호선, "저나트륨혈증에 의한 복합부분발작 뇌전증지속상태", 대한신경과학회지, 30(2), pp.125~127 (2012), 대한신경과학회[DOI]

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