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논문KCI 등재

피질기저핵변성 환자의 신경심리검사 및 양전자단층촬영 소견

Neuropsychology and PET Findings of Corticobasal Degeneration

백민재|김상윤|한문구|임준성|김정은
대한신경과학회 (Korean Neurological Association)|2005.06|대한신경과학회지 (Journal of the Korean Neurological Association)|제23권 제3호|pp. 341-347

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참고문헌

주제분류신경과학

초록

Abstract

Background: Corticobasal degeneration (CBD) is a rare neurodegenerative disorder involving the cortical and subcortical areas enabling it to cause abnormalities of both cognition and movement. In some reports, CBD has been known to develop variable degrees of intellectual, memory and language impairment. However, detailed neuropsychological assessments of CBD up to now have been few. We conducted a detailed neuropsychological investigation and FDG-PET to delineate the pattern of neuropsychological dysfunction of CBD and to correlate neuropsychological dysfunction with FDG-PET findings. Methods: All 6 patients (5; right handedness, 1; left handedness) were diagnosed with CBD using clinical criteria. All the patients underwent detailed neuropsychological and brain FDG-PET tests. Results: Neuropsychological tests showed multiple cognitive dysfunctions with moderate memory impairment. FDG-PET scans showed asymmetric decreased metabolism in bilateral fronoto-temporo-parietal cortical and subcortical areas. The extent of asymmetricity was greater on the subcortical than cortical areas. Unlike previous reports, the medial temporal and fronto-parietal metabolisms were similarly depressed. Conclusions: All CBD patients displayed prominent deficits on mostly cognitive domains. FDG-PET may explain the relation between cognitive dysfunctions and cortical hypometabolism and help differentiate CBD with other dementing disorders.

참고문헌 (22)

  1. "Neuropsychiatric features of corticobasal degeneration", 65, pp.717~721 (1998)
  2. "Neuropsychological functioning in cortical-basal ganglionic degeneration:Differentiation from Alzheimer's disease", 46, pp.720~726 (1996)
  3. "Dementia as the most common presentation of cortical-basal ganglionic degeneration", 53, pp.1969~1974 (1999)
  4. "Corticobasal Degeneration.Clinical Diagnostic Criteria", 53, pp.29~34 (2000)
  5. "Corticdentatonigral degeneration with neuronal achromasia", 18, pp.20~33 (1968)
  6. "Dementia with Parkinsonism:Corticobasal Degeneration", 1, pp.89~9 (2002)
  7. "Corticobasal degeneration:decreased and asymmetrical glucose consumption as studied with PET", 7, pp.348~354 (1992)
  8. "Corticobasal degeneration.A clinical study of 36 cases", 117, pp.1183~1196 (1994)
  9. "Corticobasal degeneration", 112, pp.1171~1192 (1989)
  10. "Corticobasal degeneration:A unique pattern of regional cortical oxygen hypometabolism and striatal fluorodepa uptake demonstrated by positron emission tomography", 114, pp.541~556 (1991)
  11. "Atrophy of the corpus callosum,cortical hypometabolism,and cognitive impairment in corticobasal degeneration", 55, pp.609~614 (1998)
  12. "The metaboli landscape of corticobasal ganglionic degeneration:regional asymmetries studied with positron emission tomography", 54, pp.856~862 (1991)
  13. "Comparison of brain perfusion in corticobasal degeneration and Alzheimer's disease", 12, pp.226~231 (2001)
  14. "Pathologically confirmed corticobasal degeneration presenting with visuospatial dysfunction", 61, pp.1134~1135 (2003)
  15. "Language function and dysfunction in corticobasal degeneration", 61, pp.493~499 (2003)
  16. "The corticobasal degeneration syndrome overlaps progressive aphasia and frontotemporal dementia", 55, pp.1368~1375 (2000)
  17. "Corticobasal degeneration:neuropathologic and clinical heterogeneity", 48, pp.959~969 (1997)
  18. "Language function and dysfunction in corticobasal degeneration", 62, pp.1238~ (2004)
  19. "Accuracy of the clinical diagnosis of corticobasal degeneration:a clinicopathologic study", 48, pp.119~125 (1997)
  20. "Clinical syndrome of corticobasal degeneration", 13, pp.565~573 (1995)
  21. "Apraxia in corticobasal degeneration", 40, pp.336~354 (1999)
  22. "A report of two overlap cases and review of literature", pp.304~312 (2000)

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