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호산구 척수염을 보인 개회충증

Eosinophilic Myelitis Associated With Toxocariasis

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초록

Infection with Toxocara canis evokes various symptoms by migration of the larva via hematogenic infiltration, but CNS involvement has rarely been documented. We describe a 63-year-old man who had eosinophilic myelitis associated with T. canis. He had subacute progressive lower body paresthesia. Spine MR revealed that the intramedullary lesion was in the thoracic cord. CSF analysis showed many eosinophils and elevated antibody titers to T. canis. These results indicate that parasitic infection should be considered as a possible cause of subacute myelitis.

Abstract

Infection with Toxocara canis evokes various symptoms by migration of the larva via hematogenic infiltration, but CNS involvement has rarely been documented. We describe a 63-year-old man who had eosinophilic myelitis associated with T. canis. He had subacute progressive lower body paresthesia. Spine MR revealed that the intramedullary lesion was in the thoracic cord. CSF analysis showed many eosinophils and elevated antibody titers to T. canis. These results indicate that parasitic infection should be considered as a possible cause of subacute myelitis.

참고문헌 (10)

  1. Goffette S, "Eosinophilic pleocytosis and myelitis related to Toxocara canis infection", Eur J Neurol, 7, pp.703~706 (2000)
  2. Hyun-YoungPARK, "A seroepidemiological survey for toxocariasis in apparently healthy residents in Gangwon-do, Korea", The Korean Journal of Parasitology, 40(3), pp.113~117 (2002), 대한기생충학회
  3. Finsterer J, "Neurotoxocarosis", Rev Inst Med trop Sao Paulo, 49, pp.279~287 (2007)
  4. Kim YB, "Toxocariasis: An unusual cause of cerebral infarction", J Korean Neurol Assoc, 21, pp.651~654 (2003)
  5. Eberhardt O, "Eosinophilic meningomyelitis in toxocariasis: Case report and review of the literature", Clin Neurol Neurosurg, 107, pp.432~438 (2005)
  6. Yun DJ, "Toxocara canis myelitis: An important cause of atopic myelitis", J Korean Neurol Assoc, 25(2), pp.40~ (2007)
  7. Queiroz L de S, "Massive spinal cord necrosis in schistosomiasis", Arch Neurol, 36, pp.517~519 (1979)
  8. Strupp M, "Meningomyelitis in a case of toxocariasis with markedly isolated CSF eosinophilia and an MRI-documented thoracic cord lesion", J Neurol, 246, pp.741~744 (1999)
  9. "The expanded spectrum of toxocaral disease", Lancet, 1, pp.692~695 (1988)
  10. Glickman LT, "Cypess R. Evaluation of serodiagnostic tests for visceral larva migrans", Am J Trop Med Hyg, 27, pp.492~498 (1978)

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