기립 시에 어지럼을 주소로 내원한 환자의 자율신경 기능검사의 분석
Analysis of Autonomic Function Tests in Patients with Orthostatic Dizziness
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Background and Objectives Orthostatic dizziness (OD) is defined as dizziness provoked by standing up from a supine or sitting position. It can be caused by the abnormality of autonomic nerve function system as well as vestibular system. We studied the autonomic nerve function in patients with OD. Subjects and Method The authors reviewed the medical records of 50 OD patients who showed normal findings of vestibular function test and brain magnetic resonance imaging. Of the 50 patients, 34 patients were enrolled in this study. We performed a standardized autonomic function test to 34 OD patients. Results The result of autonomic nerve function test revealed abnormal findings in 26 (76%) of the 34 patients. Tests performed were for the following: sympathetic failure, including abnormal decrease in blood pressure during tilt table test, Valsalva maneuver, sympathetic skin response and heart rate response to deep breathing. Conclusion Autonomic dysfunction is frequently found in patients with OD after excluding other causes with extensive investigations. Sympathetic failure or hyperactivity may be postulated as one of the possible causes of OD. Autonomic function test could be useful in understanding the mechanism of OD and treatment of OD in patients. Korean J Otorhinolaryngol-Head Neck Surg 2016;59(6):437-41
Abstract
Background and Objectives Orthostatic dizziness (OD) is defined as dizziness provoked by standing up from a supine or sitting position. It can be caused by the abnormality of autonomic nerve function system as well as vestibular system. We studied the autonomic nerve function in patients with OD. Subjects and Method The authors reviewed the medical records of 50 OD patients who showed normal findings of vestibular function test and brain magnetic resonance imaging. Of the 50 patients, 34 patients were enrolled in this study. We performed a standardized autonomic function test to 34 OD patients. Results The result of autonomic nerve function test revealed abnormal findings in 26 (76%) of the 34 patients. Tests performed were for the following: sympathetic failure, including abnormal decrease in blood pressure during tilt table test, Valsalva maneuver, sympathetic skin response and heart rate response to deep breathing. Conclusion Autonomic dysfunction is frequently found in patients with OD after excluding other causes with extensive investigations. Sympathetic failure or hyperactivity may be postulated as one of the possible causes of OD. Autonomic function test could be useful in understanding the mechanism of OD and treatment of OD in patients. Korean J Otorhinolaryngol-Head Neck Surg 2016;59(6):437-41
참고문헌 (19)
- Radtke A, "Prevalence and complications of orthostatic dizziness in the general population", Clin Auton Res, 21(3), pp.161~168 (2011)
- Yates BJ, "Integration of somatic and visceral inputs by the brainstem: functional considerations", Exp Brain Res, 119(3), pp.269~275 (1998)
- "Arch Med Res", 2003, 200~204
- Lee H, "Autonomic dysfunction in chronic persistent dizziness", J Neurol Sci, 344(1-2), pp.165~170 (2014)
- Freeman R, "Assessment of cardiovascular autonomic function", Clin Neurophysiol, 117(4), pp.716~730 (2006)
- Borst C, "Mechanisms of initial heart rate response to postural change", Am J Physiol, 243(5), pp.H676~H681 (1982)
- Wieling W, "Reflex control of heart rate in normal subjects in relation to age: a data base for cardiac vagal neuropathy", Diabetologia, 22(3), pp.163~166 (1982)
- Ravits JM, "AAEM minimonograph #48: autonomic nervous system testing", Muscle Nerve, 20(8), pp.919~937 (1997)
- Benditt DG, "Tilt table testing for assessing syncope. American College of Cardiology", J Am Coll Cardiol, 28(1), pp.263~275 (1996)
- Vetrugno R, "Sympathetic skin response: basic mechanisms and clinical applications", Clin Auton Res, 13(4), pp.256~270 (2003)
- Gutrecht JA, "Sympathetic skin response", J Clin Neurophysiol, 11(5), pp.519~524 (1994)
- Furman JM, "Clinical evidence that the vestibular system participates in autonomic control", J Vestib Res, 8(1), pp.27~34 (1998)
- Yates BJ, "Vestibular autonomic regulation:overview and conclusions of a recent workshop at the University of Pittsburgh", J Vestib Res, 8(1), pp.1~5 (1998)
- Ryder RE, "Which battery of cardiovascular autonomic function tests?", Diabetologia, 33(3), pp.177~179 (1990)
- Ewing DJ, "The value of cardiovascular autonomic function tests: 10 years experience in diabetes", Diabetes Care, 8(5), pp.491~498 (1985)
- Kim HA, "Spectrum of autonomic dysfunction in orthostatic dizziness", Clin Neurophysiol, 125(6), pp.1248~1254 (2014)
- Kerman IA, "Patterning of sympathetic nerve activity in response to vestibular stimulation", Brain Res Bull, 53(1), pp.11~16 (2000)
- Kerman IA, "Vestibular stimulation leads to distinct hemodynamic patterning", Am J Physiol Regul Integr Comp Physiol, 279(1), pp.R118~R125 (2000)
- Maser RE, "Cardiovascular autonomic neuropathy due to diabetes mellitus: clinical manifestations, consequences, and treatment", J Clin Endocrinol Metab, 90(10), pp.5896~5903 (2005)
