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비경련뇌전증지속상태로 발현한 신경매독

Neurosyphilis Presenting with Non-Convulsive Status Epilepticus

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주제분류신경과학

초록

Neurosyphilis is an infectious disease of the central nervous system caused by Treponema pallidum spirochete. There are several case reports on atypical manifestations of neurosyphilis, involving progressive cognitive dysfunction and seizures similar to those in herpes encephalitis. Seizures are common in patients with neurosyphilis, but they are usually associated with a positive Jarisch-Herxheimer reaction and status epilepticus is atypical as an initial manifestation of neurosyphilis. Here, we report on neurosyphilis patient whose initial symptom was nonconversive status epilepticus

Abstract

Neurosyphilis is an infectious disease of the central nervous system caused by Treponema pallidum spirochete. There are several case reports on atypical manifestations of neurosyphilis, involving progressive cognitive dysfunction and seizures similar to those in herpes encephalitis. Seizures are common in patients with neurosyphilis, but they are usually associated with a positive Jarisch-Herxheimer reaction and status epilepticus is atypical as an initial manifestation of neurosyphilis. Here, we report on neurosyphilis patient whose initial symptom was nonconversive status epilepticus

참고문헌 (6)

  1. Scheld WM, "Infections ofthe Central Nervous System", pp.669~683 (1997), Lippincott-Raven Publishers
  2. Hooshmand H, "Seizure disorders associated with neurosyphilis", Dis Nerv Syst, 37, pp.133~136 (1976)
  3. Bash S, "Mesiotemporal T2-weighted hyperintensity:neurosyphilis mimicking herpes encephalitis", ANJR Am J Neuroradiol, 22, pp.314~316 (2001)
  4. Kojan S, "Nonconvulsive status epilepticus resulting from Jarisch-Herxheimer reaction in a patient with neurosyphilis", Clin Electroencephalogr, 31, pp.138~140 (2000)
  5. Ances BM, "Neurosyphilis and status epilepticus: case report and literature review", Epilepsy Res, 59, pp.67~70 (2004)
  6. Evan S, "Neurosyphilis", South Med J, 95, pp.1083~1087 (2002)

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