수면클리닉에 방문하는 한국인 환자들의 수면무호흡증에 대한 위험요인
Clinical Risk Factors for Sleep Apnea in a Korean Sleep Clinic
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초록
Background: Sleep apnea is a common sleep disorder. Since polysomnography is essential for the diagnosis of sleep apnea, patient screening or selection is an important issue in the sleep clinic. The purpose of this study was to investigate the clinical risk factors of sleep apnea in a representative sleep clinic in South Korea. Methods: The medical records of the 7,559 adult patients who visited the sleep clinic from 2009 to 2018 were reviewed. We investigated the demographic data and the results of the sleep questionnaires and polysomnography to determine clinical risk factors of sleep apnea for patients at the sleep clinic. Apnea-hypopnea index over 15 was regarded as clinically significant sleep apnea. Results: A total of 4,581 patients were finally analyzed. In order of significance, age (odds ratio [OR]=1.224 from 50 to 64, p=0.027; OR=1.858 in 65 or more, p<0.001), sex (male) (OR=5.900, p<0.001), body mass index (OR=2.833 from 25 to 29.9 kg/m2, p<0.001; OR=9.388 over 30 kg/m2, p<0.001) and hypertension (OR=1.537, p<0.001) were independent risk factors of sleep apnea. Conclusions: In South Korea, it is necessary to specify the risk factors of sleep apnea according to the health related characteristics of Koreans. Further research to develop new instruments for screening sleep apnea in Korean sleep clinics is needed.
Abstract
Background: Sleep apnea is a common sleep disorder. Since polysomnography is essential for the diagnosis of sleep apnea, patient screening or selection is an important issue in the sleep clinic. The purpose of this study was to investigate the clinical risk factors of sleep apnea in a representative sleep clinic in South Korea. Methods: The medical records of the 7,559 adult patients who visited the sleep clinic from 2009 to 2018 were reviewed. We investigated the demographic data and the results of the sleep questionnaires and polysomnography to determine clinical risk factors of sleep apnea for patients at the sleep clinic. Apnea-hypopnea index over 15 was regarded as clinically significant sleep apnea. Results: A total of 4,581 patients were finally analyzed. In order of significance, age (odds ratio [OR]=1.224 from 50 to 64, p=0.027; OR=1.858 in 65 or more, p<0.001), sex (male) (OR=5.900, p<0.001), body mass index (OR=2.833 from 25 to 29.9 kg/m2, p<0.001; OR=9.388 over 30 kg/m2, p<0.001) and hypertension (OR=1.537, p<0.001) were independent risk factors of sleep apnea. Conclusions: In South Korea, it is necessary to specify the risk factors of sleep apnea according to the health related characteristics of Koreans. Further research to develop new instruments for screening sleep apnea in Korean sleep clinics is needed.
참고문헌 (17)
- Dempsey JA, "Pathophysiology of sleep apnea", Physiol Rev, 90, pp.47~112 (2010)
- Veasey SC, "Obstructive sleep apnea in adults", N Engl J Med, 380, pp.1442~1449 (2019)
- Yaggi HK, "Obstructive sleep apnea as a risk factor for stroke and death", N Engl J Med, 353, pp.2034~2041 (2005)
- Senaratna CV, "Prevalence of obstructive sleep apnea in the general population : a systematic review", Sleep Med Rev, 34, pp.70~81 (2017)
- Jackson M, "Prevalence and correlates of sleep apnea among US male veterans, 2005-2014", Prev Chronic Dis, 14, pp.E47~ (2017)
- Chiu HY, "Diagnostic accuracy of the Berlin questionnaire, STOP-BANG, STOP, and Epworth sleepiness scale in detecting obstructive sleep apnea : a bivariate meta-analysis", Sleep Med Rev, 36, pp.57~70 (2017)
- Kim KT, "Real-world STOPBANG: how useful is STOPBANG for sleep clinics?", Sleep Breath (2019)
- Patil SP, "Treatment of adult obstructive sleep apnea with positive airway pressure : an American academy of sleep medicine systematic review, meta-analysis, and GRADE assessment", J Clin Sleep Med, 15, pp.301~334 (2019)
- Oh SM, "A study on the standardization of the hospital anxiety and depression scale for Koreans : a comparison of normal, depressed and anxious groups", J Korean Neuropsychiatr Assoc, 38, pp.289~296 (1999)
- Han CW, "Development of the Korean version of Short-Form 36-Item Health Survey : health related QOL of healthy elderly people and elderly patients in Korea", Tohoku J Exp Med, 203, pp.189~194 (2004)
- Jo SA, "Usefulness of Beck Depression Inventory(BDI)in the Korean elderly population", Int J Geriatr Psychiatry, 22, pp.218~223 (2007)
- Cho YW, "The reliability and validity of the Korean version of the Epworth sleepiness scale", Sleep Breath, 15, pp.377~384 (2011)
- Sohn SI, "The reliability and validity of the Korean version of the Pittsburgh sleep quality index", Sleep Breath, 16, pp.803~812 (2012)
- 조용원, "Validation of a Korean Version of the Insomnia Severity Index", Journal of Clinical Neurology, 10(3), pp.210~215 (2014), 대한신경과학회[DOI]
- Earl DE, "Predictors of moderate to severe obstructive sleep apnea: identification of sex differences", Sleep Breath, pp.1~8 (2019)
- Neelapu BC, "Craniofacial and upper airway morphology in adult obstructive sleep apnea patients : a systematic review and meta-analysis of cephalometric studies", Sleep Med Rev, 31, pp.79~90 (2017)
- Chiao W, "Trends in sleep studies performed for medicare beneficiaries", Laryngoscope, 127, pp.2891~2896 (2017)
