스테로이드 치료로 호전된 COVID-19 (BNT162b) 백신 후 세포독성뇌들보병터 환자
CLOCC Patient after COVID-19 (BNT162b) Vaccine Improved by Steroid Treatment
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초록
Cytotoxic lesions of the corpus callosum (CLOCC) are secondary lesions on corpus callosum caused by cytokinopathy of callosal neurons and microglia. Fever, headache, and digestive disturbances are common symptoms. Reversible and hyperintense signals on fluid‐attenuated inversion recovery imaging, diffusion‐weighted imaging (DWI) and decreased apparent diffusion coefficient are typical features of magnetic resonance imaging. Herein, we report a rare case of CLOCC caused by COVID19 vaccination (BNT162b) and discharged without no neurologic symptoms due to prompt treatment.
Abstract
Cytotoxic lesions of the corpus callosum (CLOCC) are secondary lesions on corpus callosum caused by cytokinopathy of callosal neurons and microglia. Fever, headache, and digestive disturbances are common symptoms. Reversible and hyperintense signals on fluid‐attenuated inversion recovery imaging, diffusion‐weighted imaging (DWI) and decreased apparent diffusion coefficient are typical features of magnetic resonance imaging. Herein, we report a rare case of CLOCC caused by COVID19 vaccination (BNT162b) and discharged without no neurologic symptoms due to prompt treatment.
참고문헌 (10)
- Tetsuka S, "Reversible lesion in the splenium of the corpus callosum", Brain Behav, 9, pp.e01440~ (2019)
- Starkey J, "Cytotoxic lesions of the corpus callosum that show restricted diffusion : mechanisms, caus-es, and manifestations", Radiographics, 37, pp.562~576 (2017)
- Maeda M, "Reversible splenial lesion with restricted diffusion in a wide spec-trum of diseases and conditions", J Neuroradiol, 33, pp.229~236 (2006)
- Moreau A, "Cytotoxic lesions of the corpus callosum(CLOCCs)associated with SARS-CoV-2 infection", J Neurol, 268, pp.1592~1594 (2021)
- Takanashi J, "Clinically mild encephalitis with a reversible splenial lesion(MERS)after mumps vaccination", J Neurol Sci, 349, pp.226~228 (2015)
- Youn Taeho, "Cytotoxic Lesion of the Corpus Callosum (CLOCCs) after SARS-CoV-2 mRNA Vaccination", Journal of Korean Medical Science, 36(31), pp.1~2 (2021), 대한의학회[DOI]
- Notebaert A, "Expanding the spectrum of MERS type 2 lesions, a particular form of encephalitis", Pediatr Neurol, 48, pp.135~138 (2013)
- Rodrigo R, "Control of brain glutamine synthesis by NMDA receptors", Front Biosci, 12, pp.883~890 (2007)
- Doherty MJ, "Clinical implications of splenium magnetic resonance imaging signal changes", Arch Neurol, 62, pp.433~437 (2005)
- Li S, "Infarction of the corpus callosum : a retrospective clinical investigation", PLoS One, 10, pp.e0120409~ (2015)