비경련뇌전증지속상태로 발현된 메토트렉세이트유발백질뇌병증
Non-Convulsive Status Epilepticus as a Manifestation of Methotrexate-Induced Leukoencephalopathy
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Methotrexate (MTX) is an antimetabolite used in the treatment of leukemia and autoimmune disease. Careful observation of MTX concentration should be performed as side effects such as seizure, headache, limb paralysis, and confusion are found in MTXinduced leukoencephalopathy. To our knowledge, there was no reported case of nonconvulsive status epilepticus as a manifestation of MTXinduced leukoencephalopathy in South Korea. Here, we report a 54yearold patient that was diagnosed with nonconvulsive status epilepticus after longterm use of MTX.
Abstract
Methotrexate (MTX) is an antimetabolite used in the treatment of leukemia and autoimmune disease. Careful observation of MTX concentration should be performed as side effects such as seizure, headache, limb paralysis, and confusion are found in MTXinduced leukoencephalopathy. To our knowledge, there was no reported case of nonconvulsive status epilepticus as a manifestation of MTXinduced leukoencephalopathy in South Korea. Here, we report a 54yearold patient that was diagnosed with nonconvulsive status epilepticus after longterm use of MTX.
참고문헌 (10)
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