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급격히 진행하는 뇌병증을 보인 혈관내큰B세포비호지킨임파종

Intravascular Large B-cell Lymphoma Presenting as Rapidly Progressive Encephalopathy

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초록

Intravascular large B-cell lymphoma (IVLBCL) is a rare form of non-Hodgkin’s lymphoma that selectively involves the lumina of vessels, and may present as ischemic stroke. A 62-yearold man presented with progressive aphasia, dementia, seizure and stroke-like symptom. Brain magnetic resonance imaging revealed dynamic progressive fluid attenuated inversion recovery lesions and multiple punctate microbleeds in the bilateral subcortical region. A kidney biopsy revealed IVLBCL. We report a patient with IVLBCL presenting as rapidly progressive encephalopathy.

Abstract

Intravascular large B-cell lymphoma (IVLBCL) is a rare form of non-Hodgkin’s lymphoma that selectively involves the lumina of vessels, and may present as ischemic stroke. A 62-yearold man presented with progressive aphasia, dementia, seizure and stroke-like symptom. Brain magnetic resonance imaging revealed dynamic progressive fluid attenuated inversion recovery lesions and multiple punctate microbleeds in the bilateral subcortical region. A kidney biopsy revealed IVLBCL. We report a patient with IVLBCL presenting as rapidly progressive encephalopathy.

참고문헌 (10)

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  6. Richie MB, "Susceptibility-weighted imaging of intravascular lymphoma of the central nervous system", JAMA Neurol, 79, pp.86~87 (2022)
  7. Usuda D, "Autopsy-proven intravascular lymphoma presenting as rapidly recurrent strokes", Case Rep Oncol, 9, pp.148~153 (2016)
  8. Ponzoni M, "Intravascular lymphoma : a neoplasm of ‘homeless’ lymphocytes?", Hematol Oncol, 24, pp.105~112 (2006)
  9. Boslooper K, "Intravascular lymphoma as an unusual cause of multifocal cerebral infarctions discovered on FDG-PET", CT, 2010, pp.68, 261~264
  10. Matsue K, "Random skin biopsy and bone marrow biopsy for diagnosis of intravascular large B cell lymphoma", Ann Hematol, 90, pp.417~421 (2011)

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