Binge Drinking and Its Relation to Metabolic Syndrome in Korean Adult Men
1
조회
0
다운로드
6
인용
0
참고문헌
키워드
초록
Background: It is reported that heavy drinking increases the risk of metabolic syndrome. But there have been few studies on the relationship between the intensity of drinking and metabolic syndrome when drinking the same amount of alcohol. This study aimed to assess the relationship between the frequency of binge drinking and metabolic syndrome in Korean adult men.Methods: From the database of the 4th and 5th Korea National Health and Nutrition Examination Survey conducted in 2007–2010, data of 8,305 adult men (≥19 years of age) was included in this analysis. Cross-sectional relationship between the frequency of binge drinking and metabolic syndrome was investigated adjusting for pure alcohol consumed per day.Results: Adjusting for various confounders including pure alcohol consumed per day, the adjusted odds ratio for metabolic syndrome in those in higher frequency (more than 1/wk) binge drinking group was 1.62 (95% confidence interval, 1.30 to 2.03; P for trend = <0.001) compared to those in the non-binge drinking group. Through analysis of the relationship between pure alcohol consumed per day and metabolic syndrome, it was found that pure alcohol consumed per day had a positive relation to metabolic syndrome in the higher frequency binge drinking group (P for trend = 0.041). The relationship was inverse in the non-binge drinking group (P for trend = 0.002).Conclusion: Our study found a positive relationship between frequency of binge drinking and metabolic syndrome in adult men. And the effect of drinking on metabolic syndrome may depend on the frequency of binge drinking. Further studies are required to confirm this association.
Abstract
Background: It is reported that heavy drinking increases the risk of metabolic syndrome. But there have been few studies on the relationship between the intensity of drinking and metabolic syndrome when drinking the same amount of alcohol. This study aimed to assess the relationship between the frequency of binge drinking and metabolic syndrome in Korean adult men.Methods: From the database of the 4th and 5th Korea National Health and Nutrition Examination Survey conducted in 2007–2010, data of 8,305 adult men (≥19 years of age) was included in this analysis. Cross-sectional relationship between the frequency of binge drinking and metabolic syndrome was investigated adjusting for pure alcohol consumed per day.Results: Adjusting for various confounders including pure alcohol consumed per day, the adjusted odds ratio for metabolic syndrome in those in higher frequency (more than 1/wk) binge drinking group was 1.62 (95% confidence interval, 1.30 to 2.03; P for trend = <0.001) compared to those in the non-binge drinking group. Through analysis of the relationship between pure alcohol consumed per day and metabolic syndrome, it was found that pure alcohol consumed per day had a positive relation to metabolic syndrome in the higher frequency binge drinking group (P for trend = 0.041). The relationship was inverse in the non-binge drinking group (P for trend = 0.002).Conclusion: Our study found a positive relationship between frequency of binge drinking and metabolic syndrome in adult men. And the effect of drinking on metabolic syndrome may depend on the frequency of binge drinking. Further studies are required to confirm this association.
참고문헌 (22)
- Zimmet P, "A New International Diabetes Federation (IDF) worldwide definition of the metabolic syndrome: the rationale and the results", Rev Esp Cardiol (Engl Ed), 58, pp.1371~1375 (2005)
- Gupta AK, "AngloScandinavian Cardiac Outcomes Trial-Blood Pressure Lowering Arm Investigators. Metabolic syndrome, independent of its components, is a risk factor for stroke and death but not for coronary heart disease among hypertensive patients in the ASCOT-BPLA", Diabetes Care, 33, pp.1647~1651 (2010)
- Lim S, "Increasing Prevalence of Metabolic Syndrome in Korea The Korean National Health and Nutrition Examination Survey for 1998-2007", DIABETES CARE, 34(6), pp.1323~1328 (2011), AMER DIABETES ASSOC
- (2005)[URL]
- Zhu S, "Lifestyle behaviors associated with lower risk of having the metabolic syndrome", Metabolism, 53, pp.1503~1511 (2004)
- Rosell M, "Low prevalence of the metabolic syndrome in wine drinkers: is it the alcohol beverage or the lifestyle", Eur J Clin Nutr, 57, pp.227~234 (2003)
- Rimm EB, "Moderate alcohol intake and lower risk of coronary heart disease: meta-analysis of effects on lipids and haemostatic factors", BMJ, 319, pp.1523~1528 (1999)
- World Health Organization, "Global status report on alcohol 2004" (2004), World Health Organization
- 오지연, "한국어판 단문형 국제신처활동설문(IPAQ)의 신뢰도와 타당도", Korean Journal of Family Medicine, 28(7), pp.532~541 (2007), 대한가정의학회
- Corrao G, "Alcohol and coronary heart disease: a meta-analysis", Addiction, 95, pp.1505~1523 (2000)
- World Health Organization, "International guide for monitoring alcohol consumption and related harm" (2000), World Health Organization
- Grundy SM, "Diagnosis and management of the metabolic syndrome: an American Heart Association", National Heart, Lung, and Blood Institute Scientific Statement, 2005, pp.112, 2735~2752
- Park HS, "Appropriate waist circumference cutoff points for central obesity in Korean adults", DIABETES RES CLIN PRACT, 75(1), pp.72~80 (2007), ELSEVIER IRELAND LTD
- Fan AZ, "Lifetime alcohol drinking pattern is related to the prevalence of metabolic syndrome. The Western New York Health Study (WNYHS)", Eur J Epidemiol, 21, pp.129~138 (2006)
- Yoon YS, "Alcohol consumption and the metabolic syndrome in Korean adults: the 1998 Korean National Health and Nutrition Examination Survey", Am J Clin Nutr, 80, pp.217~224 (2004)
- 오상우, "음주가 비만 및 대사증후군에 미치는 영향", 대한비만학회지, 18(1), pp.1~7 (2009), 대한비만학회
- Suter PM, "Is alcohol consumption a risk factor for weight gain and obesity", Crit Rev Clin Lab Sci, 42, pp.197~227 (2005)
- Xu D, "Alcohol-related diols cause acute insulin resistance in vivo", Metabolism, 47, pp.1180~1186 (1998)
- Coca A, "Chronic alcohol intake induces reversible disturbances on cellular Na+ metabolism in humans: its relationship with changes in blood pressure", Alcohol Clin Exp Res, 16, pp.714~720 (1992)
- Randin D, "Suppression of alcohol-induced hypertension by dexamethasone", N Engl J Med, 332, pp.1733~1737 (1995)
- Savolainen MJ, "Effects of alcohol on lipoproteins in relation to coronary heart disease", Curr Opin Lipidol, 6, pp.243~250 (1995)
- Lindtner C, "Binge drinking induces whole-body insulin resistance by impairing hypothalamic insulin action", Sci Transl Med, 5, pp.170~114 (2013)