Osteoarthritis Affects Health-Related Quality of Life in Korean Adults with Chronic Diseases: The Korea National Health and Nutritional Examination Surveys 2009–2013
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Background: Osteoarthritis (OA) is a chronic disease that commonly afflicts the elderly. This disease reduces thehealth-related quality of life (HRQoL) and causes a significant social burden. Whether the effect of coexistingchronic conditions on HRQoL varies according to the presence of OA remains unclear. Therefore, this study aimedto investigate this notion. Methods: A total of 13,395 participants were identified from the 2009–2013 Korean National Health and NutritionExamination Survey for analysis. HRQoL was assessed using the European quality of life-5 dimensions (EQ-5D) index. Patients with OA were defined as those diagnosed by a physician or those who displayed both, symptoms andradiological findings consistent with OA at the time of the survey. Associations between OA and 8 chronic conditionswere tested using regression analysis. Results: The EQ-5D index was lower in patients with OA than in those without (mean difference, -0.145; 95% confidenceinterval [CI], -0.138 to -0.151; P<0.001). Most patients with OA and chronic conditions showed a lower scorethan those without. EQ-5D was particularly lower in OA patients with hypertension, dyslipidemia, stroke, and renalfailure. The estimated β coefficient for the interaction term was significant in renal failure (-0.034; 95% CI, -0.055 to-0.012), after adjusting for demographic and socio-economic variables. Conclusion: OA significantly affects HRQoL of Korean elderly individuals alone or when combined with other conditions. OA combined with renal failure is particularly detrimental. These results indicate the importance of managingOA, which is an underestimated disease in public health surveys.
Abstract
Background: Osteoarthritis (OA) is a chronic disease that commonly afflicts the elderly. This disease reduces thehealth-related quality of life (HRQoL) and causes a significant social burden. Whether the effect of coexistingchronic conditions on HRQoL varies according to the presence of OA remains unclear. Therefore, this study aimedto investigate this notion. Methods: A total of 13,395 participants were identified from the 2009–2013 Korean National Health and NutritionExamination Survey for analysis. HRQoL was assessed using the European quality of life-5 dimensions (EQ-5D) index. Patients with OA were defined as those diagnosed by a physician or those who displayed both, symptoms andradiological findings consistent with OA at the time of the survey. Associations between OA and 8 chronic conditionswere tested using regression analysis. Results: The EQ-5D index was lower in patients with OA than in those without (mean difference, -0.145; 95% confidenceinterval [CI], -0.138 to -0.151; P<0.001). Most patients with OA and chronic conditions showed a lower scorethan those without. EQ-5D was particularly lower in OA patients with hypertension, dyslipidemia, stroke, and renalfailure. The estimated β coefficient for the interaction term was significant in renal failure (-0.034; 95% CI, -0.055 to-0.012), after adjusting for demographic and socio-economic variables. Conclusion: OA significantly affects HRQoL of Korean elderly individuals alone or when combined with other conditions. OA combined with renal failure is particularly detrimental. These results indicate the importance of managingOA, which is an underestimated disease in public health surveys.
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