Effect of Coffee Consumption on the Progression of Type 2 Diabetes Mellitus among Prediabetic Individuals
2
조회
0
다운로드
2
인용
0
참고문헌
키워드
초록
Background: A previous large-scale cohort study investigated the relationship between coffee intake and the progression of diabetes mellitus in the United States. However, studies on the effects of coffee on diabetes are rare in South Korea. Therefore, this study assessed the amount and method of coffee intake in Koreans in order to determine if coffee intake has a prophylactic effect on diabetes progression.Methods: This study included 3,497 prediabetic patients from a single medical institution, with glycated hemoglobin levels ranging from 5.7% to 6.4%. Cross-tabulation and Kaplan-Meier survival analyses were performed to compare patients with and without diabetes progression based on the frequency and method of coffee intake. Cox proportional hazard analysis was performed to correct for confounding variables. Results: The observation period (mean±standard deviation) was 3.7±2.3 years. Kaplan-Meier survival analysis revealed that the risk of diabetes progression was lowest in patients who drank black coffee three or more times per day (P=0.036). However, correction for confounding variables in Cox proportional hazard analysis revealed that, while the risk was lower for the patients who typically consumed black coffee than for those who mixed creamer and sugar into their coffees, the difference was not significant. Conclusion: The results of this study suggest that drinking coffee without sugar and creamer at least three times daily has the greatest preventive effect on diabetes onset.
Abstract
Background: A previous large-scale cohort study investigated the relationship between coffee intake and the progression of diabetes mellitus in the United States. However, studies on the effects of coffee on diabetes are rare in South Korea. Therefore, this study assessed the amount and method of coffee intake in Koreans in order to determine if coffee intake has a prophylactic effect on diabetes progression.Methods: This study included 3,497 prediabetic patients from a single medical institution, with glycated hemoglobin levels ranging from 5.7% to 6.4%. Cross-tabulation and Kaplan-Meier survival analyses were performed to compare patients with and without diabetes progression based on the frequency and method of coffee intake. Cox proportional hazard analysis was performed to correct for confounding variables. Results: The observation period (mean±standard deviation) was 3.7±2.3 years. Kaplan-Meier survival analysis revealed that the risk of diabetes progression was lowest in patients who drank black coffee three or more times per day (P=0.036). However, correction for confounding variables in Cox proportional hazard analysis revealed that, while the risk was lower for the patients who typically consumed black coffee than for those who mixed creamer and sugar into their coffees, the difference was not significant. Conclusion: The results of this study suggest that drinking coffee without sugar and creamer at least three times daily has the greatest preventive effect on diabetes onset.
참고문헌 (19)
- Kim SH, "Coffee: more knowledge, more taste", Korean Clin Diabetes, 10, pp.250~254 (2009)
- Hitman GA, "Coffee: friend or foe for diabetes risk?", Diabet Med, 31, pp.763~ (2014)
- 김은경, "강릉과 삼척지역 주민의 커피믹스 섭취 여부에 따른 영양섭취실태 및 비만관련 신체계측치, 혈중지질패턴과의 상호관련성", 대한지역사회영양학회지, 18(2), pp.134~141 (2013), 대한지역사회영양학회
- 박주연, "과체중 여성에서 생커피두 엑기스의 섭취가 체지방 개선에 미치는 영향", Journal of Nutrition and Health, 43(4), pp.374~381 (2010), 한국영양학회
- Bhupathiraju SN, "Changes in coffee intake and subsequent risk of type 2 diabetes: three large cohorts of US men and women", Diabetologia, 57, pp.1346~1354 (2014)
- Palatini P, "Association of coffee consumption and CYP1A2 polymorphism with risk of impaired fasting glucose in hypertensive patients", Eur J Epidemiol, 30, pp.209~217 (2015)
- Tuso P., "Prediabetes and lifestyle modification: time to prevent a preventable disease", Perm J, 18, pp.88~93 (2014)
- American Diabetes Association, "Diagnosis and classification of diabetes mellitus", Diabetes Care, 33(Suppl 1), pp.S62~S69 (2010)
- "Fact sheet: evidence-based recommendations for type 2 diabetes in primary care"[URL]
- Ochoa PS, "Identification of previously undiagnosed diabetes and prediabetes in the inpatient setting using risk factor and hemoglobin A1C screening", Ann Pharmacother, 48, pp.1434~1439 (2014)
- Lee YH, "Diabetes risk score for Korean adults", J Korean Diabetes, 14, pp.6~10 (2013)
- "Fact sheet: what is the level of caffeine intake of Korean?: evaluation of the capita intake of caffeine per day" (2013)[URL]
- "Fact sheet: market report for domestic processed food products of coffee" (2013)[URL]
- Yamaji T, "Coffee consumption and glucose tolerance status in middle-aged Japanese men", Diabetologia, 47, pp.2145~2151 (2004)
- Ding M, "Caffeinated and decaffeinated coffee consumption and risk of type 2 diabetes: a systematic review and a dose-response meta-analysis", Diabetes Care, 37, pp.569~586 (2014)
- Pham NM, "Coffee and green tea consumption is associated with insulin resistance in Japanese adults", Metabolism, 63, pp.400~408 (2014)
- Chung SK, "Association between coffee drinking and tumor-markers", Korean J Fam Pract, 4, pp.56~60 (2014)
- Park YM, "Associations between irritable bowel syndrome and psychological factors in Korean high-school girls", Korean J Fam Pract, 1, pp.111~120 (2011)
- Lee SJ, "Factors associated with propensity to aggression in Korean adolescents enrolled in a middle school", Korean J Fam Pract, 1, pp.24~31 (2011)