Mammary Paget’s Disease of the Nipple: Relatively Common but Still Unknown to Many
1
조회
0
다운로드
0
인용
0
참고문헌
키워드
초록
Mammary Paget’s disease is clinically defined as skin inflammation of the nipple area and is an adenocarcinoma of the epidermis of the nipple. The pathogenesis of mammary Paget’s disease is relatively unknown; nonetheless, there are two popular theories that support the underlying carcinoma and de novo carcinogenesis. For the attend-ing medical practitioner, mammary Paget’s disease poses a diagnostic and therapeutic dilemma, especially in the absence of a clinically palpable breast mass. We report a rare case of a 48-year-old Malay woman who presented at Hospital Universiti Sains Malaysia, Kelantan, Malaysia with the symptom of skin erosion on the left nipple and un-responsiveness to multiple topical treatments. A full evaluation and assessment of the patient were conducted, and mammary Paget’s disease was diagnosed.
Abstract
Mammary Paget’s disease is clinically defined as skin inflammation of the nipple area and is an adenocarcinoma of the epidermis of the nipple. The pathogenesis of mammary Paget’s disease is relatively unknown; nonetheless, there are two popular theories that support the underlying carcinoma and de novo carcinogenesis. For the attend-ing medical practitioner, mammary Paget’s disease poses a diagnostic and therapeutic dilemma, especially in the absence of a clinically palpable breast mass. We report a rare case of a 48-year-old Malay woman who presented at Hospital Universiti Sains Malaysia, Kelantan, Malaysia with the symptom of skin erosion on the left nipple and un-responsiveness to multiple topical treatments. A full evaluation and assessment of the patient were conducted, and mammary Paget’s disease was diagnosed.
참고문헌 (10)
- Lakhani SR, "WHO classification of tumours of the breast" (2012), International Agency for Research on Cancer
- Kanitakis J, "Mammary and extramammary Paget’s disease", J Eur Acad Dermatol Venereol, 21, pp.581~590 (2007)
- Paget J, "On disease of the mammary areola preceding cancer of the mammary gland", St Bartholomew’s Hosp Rep, 10, pp.87~89 (1874)
- The Malaysian National Cancer Registry report 2007-2011: Malaysia cancer statistics, data and figures, "National Cancer Institute, Ministry of Health", National Cancer Institute, Ministry of Health Malaysia, ~ (2011)
- Lopes Filho LL, "Mammary and extramammary Paget’s disease", An Bras Dermatol, 90, pp.225~231 (2015)
- Brugues A, "Pigmented mammary Paget disease mimicking cutaneous malignant melanoma", J Am Acad Dermatol, 72, pp.e97~8 (2015)
- Liu J, "An unusual presentation of Paget’s disease of the nipple in a young woman : a case report", Int J Clin Exp Med, 8, pp.4694~4696 (2015)
- Enzo Errichetti, "Dermoscopy as a Supportive Instrument in the Early Recognition of Erosive Adenomatosis of the Nipple and Mammary Paget’s Disease", Annals of Dermatology, 29(3), pp.365~367 (2017), 대한피부과학회
- Karamchandani DM, "Pathologic-radiologic correlation in evaluation of retroareolar margin in nipple-sparing mastectomy", Virchows Arch, 466, pp.279~287 (2015)
- Marshall JK, "Conservative management of Paget disease of the breast with radiotherapy : 10-and 15-year results", Cancer, 97, pp.2142~2149 (2003)