털머위 부위별 추출물의 항산화 및 항효소 효과
Antioxidant and Antienzyme Effects of Extracts from Each Part of Farfugium japonicum
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This study aims to investigate the antioxidant and anti-enzymatic effects of Farfugium japonicum. The phy- siological activities were measured in the flowers, leaves, roots, and stems of the plant, with significant differences confirmed through Duncan’s analysis. The extraction yield in all parts exceeded 20%, surpassing the 10% industrial standard and indicating potential for industrial application. Analysis of antioxidant components revealed the highest content in the roots, followed by the flowers, leaves, and stems. Antioxidant activity tests showed superior activity in the roots, suggesting that phenolic and flavonoid compounds contributed to this effect. α-Glucosidase inhibition tests, used to assess antidiabetic effects, compared the plant parts with acarbose, a standard diabetes treatment. The roots exhibited higher activity and showed significant differences compared to those of the other plant parts. Tyrosinase inhibition tests were conducted to compare the effects of the plant with arbutin, a key ingredient in whitening cosmetics. Although all plant parts exhibited lower efficiency than those of the positive control, the roots were comparable. These findings indicate that roots demonstrate the highest physiological activity among the plant parts, similar to that of the positive control. These findings suggest the potential applications of F. japonicum roots as an antioxidant, antidiabetic, and skin-whitening.
Abstract
This study aims to investigate the antioxidant and anti-enzymatic effects of Farfugium japonicum. The phy- siological activities were measured in the flowers, leaves, roots, and stems of the plant, with significant differences confirmed through Duncan’s analysis. The extraction yield in all parts exceeded 20%, surpassing the 10% industrial standard and indicating potential for industrial application. Analysis of antioxidant components revealed the highest content in the roots, followed by the flowers, leaves, and stems. Antioxidant activity tests showed superior activity in the roots, suggesting that phenolic and flavonoid compounds contributed to this effect. α-Glucosidase inhibition tests, used to assess antidiabetic effects, compared the plant parts with acarbose, a standard diabetes treatment. The roots exhibited higher activity and showed significant differences compared to those of the other plant parts. Tyrosinase inhibition tests were conducted to compare the effects of the plant with arbutin, a key ingredient in whitening cosmetics. Although all plant parts exhibited lower efficiency than those of the positive control, the roots were comparable. These findings indicate that roots demonstrate the highest physiological activity among the plant parts, similar to that of the positive control. These findings suggest the potential applications of F. japonicum roots as an antioxidant, antidiabetic, and skin-whitening.
참고문헌 (48)
- Bai L, "Antidiabetic potential of flavonoids from traditional Chinese medicine : A review", Am J Chin Med, 47, pp.933~957 (2019)
- Benzie IFF, "The ferric reducing ability of plasma(FRAP)as a measure of ‘antioxidant power’ : The FRAP assay", Anal Biochem, 239, pp.70~76 (1996)
- Berg RVD, "Applicability of an improved trolox equivalent antioxidant capacity(TEAC)assay for evaluation of antioxidant capacity measurements of mixtures", Food Chem, 66, pp.511~517 (1999)
- Blois MS, "Antioxidant determinations by the use of a stable free radical", Nature, 181, pp.1199~1200 (1958)
- Branen AL, "Toxicology and biochemistry of butylated hydroxyanisole and butylated hydroxytoluene", J Am Oil Chem Soc, 52, pp.59~63 (1975)
- Chang YD, "Effect of chilling and gibberellin on the seed germination of leopard plant", Hortic Sci Technol, 22, pp.64~ (2004)
- Choi SY, "Toxicological studies of antioxidants, butylated hydroxytoluene(BHT)and butylated hydroxyanisole(BHA)", Korean J Food Sci Technol, 14, pp.283~288 (1982)
- Devkota HP, "Bioactive phenolic compounds from the flowers of Farfugium japonicum (L.) Kitam. Var. giganteum (Siebold et Zucc.) Kitam. (Asteraceae)", Nat Prod Res, 36, pp.4036~4039 (2022)
- Han HK, "Effects of Compositae plants on plasma glucose and lipid level in streptozotocin induced diabetic rats", J Korean Soc Food Sci Nutr, 38, pp.674~682 (2009)
- Hyong IH, "Review of reactive oxygen", J Korean Soc Phys Med, 1, pp.139~146 (2006)
- Im DY, "Antioxidative activity and tyrosinase inhibitory activity of the extract and fractions from Arcitum lappa roots and analysis of phenolic compounds", Kor J Pharmacogn, 45, pp.141~146 (2014)
- Iwashina T, "The structure and distribution of the flavonoids in plants", J Plant Res, 113, pp.287~299 (2000)
- Jang DS, "Biological activities of sesquiterpene lactones isolated from several Compositae plants. Part 3. Inhibitory activity on nitric oxide release and ACAT", Kor J Pharmacogn, 30, pp.74~78 (1999)
- Ji S, "Changes in the phenolic compounds profile, antioxidant and anti-melanogenic activity form orangs of Petasites japonicas under different extraction methods", Rev Mex Ing Quím, 19, pp.1453~1464 (2020)
- Jung DH, "Development of a model for estimating leaf area and the number of flower using leaf length and width of Farfugium japonicum Kitam", J Bio Env Con, 32, pp.115~121 (2023)
- Kang DH, "Bioactive compounds and antioxidant activity of Jeju camellia mistletoe (Korthalsella japonica Engl.)", J Life Sci, 26, pp.1074~1081 (2016)
- Kang YH, "The nitrite scavenging and electron donating ability of phenolic compounds", Korean J Food Sci Technol, 28, pp.232~239 (1996)
- Kim EJ, "Total polyphenols, total flavonoid contents, and antioxidant activity of Korean natural and medicinal plants", Korean J Food Sci Technol, 44, pp.337~342 (2012)
- Kim JH, "Antioxidant activity and inhibition activity against α-amylase and α-glucosidase of Juniperus rigida Sieb extracts", Korean J Food Preserv, 21, pp.396~403 (2014)
- Kim JS, "Antioxidant, α-glucosidase inhibitory and antimicrobial activities of extracts form Maesa japonica (Thunb.)", Korean J Medicinal Crop Sci, 22, pp.289~294 (2014)
- Kim KH, "Antidiabetic effects of banaba leaf extracts (Lagerstroemia speciosa Pers.) through solvents", J Life Sci, 18, pp.1305~1311 (2008)
- Kim SJ, "Anthocyanin and polyphenol analysis and antioxidant activity of small fruit and berries in Korea", Korean J Plant Res, 32, pp.407~414 (2019)
- Ko HM, "Biological activity investigation of supercritical fluid extract of fermented mountain ginseng adventitious root", J Adv Eng Technol, 11, pp.115~121 (2018)
- Ko HM, "Tyrosinase and α-glucosidase inhibitory activities and antioxidant effects of extracts from different parts of Hypochaeris radicata", Korean J Medicinal Crop Sci, 25, pp.139~145 (2017)
- Marinova D, "Total phenolics and flavonoids in Bulgarian fruits and vegetables", J Univ Chem Technol Metallurgy, 40, pp.255~260 (2005)
- Mo JH, "Tyrosinase inhibitory activity and melanin production inhibitory activity of the methanol extract and fractions from Dendropanax morbifera Lev", Kor J Aesthet Cosmetol, 11, pp.275~280 (2013)
- Mok JY, "Antioxidative and anti-inflammatory effects of extracts from different orangs of Cirsium japonicum var. ussuriense", Kor J Herbology, 26, pp.39~47 (2011)
- Moon GS, "Components and antioxidative activities of Buchu(Chinese chives)harvested at different times", Korean J Food Sci Technol, 35, pp.493~498 (2003)
- Na EJ, "Review of recent studies and research analysis for anti-oxidant and anti-aging materials", Asian J Beauty Cosmetol, 14, pp.481~491 (2016)
- Oh HK, "Nutritional composition and antioxidative activity of different parts of Taraxacum coreanum according to drying methods", J Korean Diet Assoc, 19, pp.389~399 (2013)
- Oh HN, "Tyrosinase inhibition antioxidant effect and cytotoxicity studies of the extracts of Cudrania tricuspidate fruit standardized in chlorogenic acid", Molecules, 24, pp.3266~ (2019)
- Oney-Montalvo JE, "Polyphenols content in Capsicum chinense fruits at different harvest times and their correlation with the antioxidant activity", Plants, 9, pp.1394~ (2020)
- Park JH, "α-Glucosidase and α-amylase inhibitory activity of compounds from roots extract of Pueraria thunbergiana", Korean J Medicinal Crop Sci, 17, pp.357~362 (2009)
- Park JY, "Effect of gamma ray irradiation on seed germination, growth and variant induction in Hosta plantaginea and Farfugium japoniucum", Flower Res J, 16, pp.128~133 (2008)
- Park SH, "A study of medicinal herbs for functional foods application nutritional composition and scopoletin analysis of Artemisia capillaries", J East Asian Soc Diet Life, 13, pp.552~560 (2003)
- Park SH, "Assessment of adequate volumetric water content for managing Farfugium japonicum (L.) Kitam. in the indoor gardens", J People Plants Environ, 26, pp.749~759 (2023)
- Park SN, "Skin aging and antioxidants", J Soc Cosmet Sci Korea, 23, pp.75~132 (1997)
- Quilantang NG, "Quantitative determination of bakkenolide D in Petasites japonicus and Farfugium japonicum by HPLC", UV, 2017, pp.23, 270~273
- Shen T, "Eremophilane sesquiterpenoids from Farfugium japonicum", Bull Korean Chem Soc, 32, pp.350~352 (2011)
- Song FL, "Total phenolic contents and antioxidant capacities of selected Chinese medicinal plants", Int J Mol Sci, 11, pp.2362~2372 (2010)
- Song JS, "Cultivation and using for garden and potted plant of leopard plant(Farfugium japonicum)native to Korea", Landscaping Tree, 82, pp.20~22 (2004)
- Tori M, "New eremophilanes from Farfugium japonicum", Tetrahedron, 66, pp.5235~5243 (2010)
- Wei Q, "Composition and antioxidative and antibacterial activities of the essential oil from Farfugium japonicum", Molecules, 28, pp.2774~ (2023)
- Wojdylo A, "Antioxidant activity and phenolic compounds in 32 selected herbs", Food Chem, 105, pp.940~949 (2007)
- Won DH, "Antioxidative effect and tyrosinase inhibitory activity of Lindera obtusiloba blume extracts", J Soc Cosmet Sci Korea, 38, pp.297~304 (2012)
- Woo NRY, "Comparison or antioxidative activities or Crotalaria sessiflora L. extracts from leaves, seed, stem and root", J Korean Soc Food Sci Nutr, 34, pp.1297~1301 (2005)
- Xu ML, "Antioxidant and anti-diabetes activity of extracts from Machilus thunbergii S. et Z", Korean J Medicinal Crop Sci, 18, pp.34~39 (2010)
- Zulueta A, "ORAC and TEAC assays comparison to measure the antioxidant capacity of food products", Food Chem, 114, pp.310~316 (2009)