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One Pot Synthesis of Bioactive Novel Cyanopyridones

Kamlesh Khokhani|Taslimahemad Khatri|Praful Patel
대한화학회|2013.08|대한화학회지 (Journal of the Korean Chemical Society)|제57권 제4호|pp. 476-482|DOI http://dx.doi.org/10.5012/jkcs.2013.57.4.476

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참고문헌

키워드

Antimicrobial activityMalononitrileCyanopyrimidonesCyanoacetamidePipyridine
주제분류화학

초록

Cyanopyridone was prepared by the condensation of cyanoacetamide, substituted arylaldehydes and malononitrile in presence of pipyridine. The structure of the synthesized compound CP 1-20 was assigned on the basis of elemental analysis, IR, 1H-NMR and mass spectroscopy. These compounds were also screened for antimicrobial activity. The Minimum Inhibitory Concentration (MIC) of all the synthesized compounds was compared with standard drugs.

Abstract

Cyanopyridone was prepared by the condensation of cyanoacetamide, substituted arylaldehydes and malononitrile in presence of pipyridine. The structure of the synthesized compound CP 1-20 was assigned on the basis of elemental analysis, IR, 1H-NMR and mass spectroscopy. These compounds were also screened for antimicrobial activity. The Minimum Inhibitory Concentration (MIC) of all the synthesized compounds was compared with standard drugs.

참고문헌 (24)

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