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미숙아에서 최적의 혈색소

Optimal Hemoglobin Level in Preterm Infants

김성신
대한신생아학회 (THE KOREAN SOCIETY OF NEONATOLOGY)|2014.05|Neonatal medicine|제21권 제2호|pp. 92-98

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참고문헌

키워드

AnemiaHemoglobinsInfant prematureErythrocyte transfusion

초록

미숙아에게서 빈혈은 매우 흔한 문제이다. 빈혈의 치료는 농축 적혈구 수혈이 기본적으로 쓰인다. 그러나 적혈구 수혈의 장점은 제한적이며, 수혈로 관련된 괴사성 장염, 심한 뇌실내 출혈, 미숙아 망막증, 감염 위험, 신경학적 발 달장애등이 보고되고 있다. 수혈의 이득 위험보다 많을지는 아직도 논란 중이며 수혈 지침도 전문가의 견해에 의존 하는 등확실한 근거가 없다. 수혈을 고려하게 되는 임상증상으로 무호흡, 빈맥, 불량한 체중증가, 산소 의존도의 증가가 있으며 환아의 출생 후 나이도 고려한다. 현재까지 수혈의 적적한 시기와 혈색소 지침이 알려져 있지 않다. 본 종설의 목적은 최근 수혈 지침을 문헌 고찰을 통하여 정리하고자 한다.

Abstract

Anemia is a common condition in preterm infants. Packed red blood cell (RBC)transfusion is used for the management of anemia; however, evidence on thebenefits of this treatment is limited. RBC transfusion in preterm infants is associatedwith necrotizing enterocolitis, severe intraventricular hemorrhage, retinopathyof prematurity, transfer of infectious agents, and negative neurodevelopmentaloutcome. Whether the benefits outweigh the risks of RBC transfusion is controversial,and guidelines on transfusion that are based on expert opinions are unclear. Clinical signs such as apnea, tachycardia, frequent desaturation, poor weight gain,and increasing oxygen requirement and postnatal age are the factors are includedin the decision to perform RBC transfusion. To date, the optimal timing andthreshold hemoglobin level for administering treatment have not been established. The purpose of this review is to summarize the current transfusion guidelines.

참고문헌 (31)

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관련 논문AI추천

미숙아에서의 적정 산소요법진현승대한신생아학회 · Neonatal medicine2014 · 제21권 제2호Comparison of Hemoglobin Correction Effects According to Storage Period and Other Factors in the Transfusion of Packed Red Blood Cells in Neonatal Intensive Care Unit Patients공섬김, 홍유라, Ji Hyun Park대한신생아학회 · Neonatal medicine2018 · 제25권 제4호The Iron Status of Very Low Birth Weight Infants Receiving Multiple Erythrocyte Transfusions during Hospitalization in the Neonatal Intensive Care UnitHeng-Mi Kim, Sook-Hyun Park대한소아소화기영양학회 · Pediatric Gastroenterology, Hepatology & Nutrition2015 · 제18권 제2호극소 저체중 출생아에서 경피적 산소포화도의 적정 범위강혜진, 김민정, 유선영, 장미영대한신생아학회 · Neonatal medicine2011 · 제18권 제2호미숙아 빈혈에 대한 Recombinant Human Erythropoietin의 효과: 예비연구박용훈, 신손문, 이경아, 하정옥영남대학교 의과대학 · Journal of Yeungnam Medical Science1994 · 제11권 제1호초극소 저체중 출생아에서 제대 용출의 효과김은선, 김진규, 박원순, 백상훈, 성세인, 신정희, 심재원, 안소윤, 유혜수, 장윤실, 정지미대한신생아학회 · Neonatal medicine2012 · 제19권 제4호

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