신생아 발작의 발견 및 진단
Detection and Diagnosis of Neonatal Seizures
1
조회
0
다운로드
0
인용
0
참고문헌
키워드
초록
Seizures are the most common clinical manifestation of a neurologic insult during the neonatal period. Neonatal seizures continue to present a diagnostic and therapeutic challenge to pediatricians because the recognition and classification of neonatal seizures remains problematic, particularly when clinicians rely only on clinical criteria. Neonatal seizures can permanently disrupt neuronal development, induce synaptic reorganization, alter plasticity, and “prime” the brain to increased damage from seizures later in life. Since neonatal seizures, particularly status epilepticus, predict an increased risk for later epilepsy and other neurologic sequelae, accurate diagnoses are needed for aggressive antiepileptic drug use. The present review summarizes the pathophysiology, etiology, and diagnosis of neonatal seizures.
Abstract
Seizures are the most common clinical manifestation of a neurologic insult during the neonatal period. Neonatal seizures continue to present a diagnostic and therapeutic challenge to pediatricians because the recognition and classification of neonatal seizures remains problematic, particularly when clinicians rely only on clinical criteria. Neonatal seizures can permanently disrupt neuronal development, induce synaptic reorganization, alter plasticity, and “prime” the brain to increased damage from seizures later in life. Since neonatal seizures, particularly status epilepticus, predict an increased risk for later epilepsy and other neurologic sequelae, accurate diagnoses are needed for aggressive antiepileptic drug use. The present review summarizes the pathophysiology, etiology, and diagnosis of neonatal seizures.
참고문헌 (19)
- Volpe JJ, "Neonatal seizures. In: Neurology of the newborn. 4th ed", pp.178~214 (2001), WB Sanders Co
- Lanska MJ, "Neonatal seizures in the United States: results of the National Hospital Discharge Survey, 1980-1991", Neuroepidemiology, 15, pp.117~125 (1996)
- Lanska MJ, "A population-based study of neonatal seizures in Fayette County, Kentucky", Neurology, 45, pp.724~732 (1995)
- Ronen GM, "The epidemiology of clinical neonatal seizures in Newfoundland: a population-based study", J Pediatr, 134, pp.71~75 (1999)
- Saliba RM, "Incidence of neonatal seizures in Harris County, Texas, 1992-1994", Am J Epidemiol, 150, pp.763~769 (1999)
- Eriksson M, "Neonatal convulsions. Incidence and causes in the Stockholm area", Acta Paediatr Scand, 68, pp.807~811 (1979)
- Wyllie E, "The treatment of epilepsy - principles & practice. 4th ed", pp.488~ (2006), Lippincott Williams & Wilkins
- Silverstein FS, "Neonatal seizures", Ann Neurol, 62, pp.112~120 (2007)
- Zupanc ML, "Neonatal seizures", Pediatr Clin North Am, 51, pp.961~978 (2004)
- Dzhala VI, "NKCC1 transporter facilitates seizures in the developing brain", Nat Med, 11, pp.1205~1213 (2005)
- Scher MS, "Neonatal seizures and brain damage", Neurol, 29, pp.381~390 (2003)
- Pisani F, "Neonatal status epilepticus vs recurrent neonatal seizures", Neurology, 69, pp.2177~2185 (2007)
- Granelli SLP, "Neonatal seizures: diagnosis, pharmacologic interventions, and outcomes", J Perinat Neonatal Nurs, 18, pp.275~287 (2004)
- Scher MS, "Controversies concerning neonatal seizures", Pediatr Clin North Am, 36, pp.281~310 (1989)
- Painter MJ, "Neonatal seizures", Pediatr Clin North Am, 33, pp.91~109 (1986)
- Scher MS, "Seizures in the newborn infant. Diagnosis, treatment and outcome", Clin Perinatol, 24, pp.735~772 (1997)
- Tharp BR, "Neonatal seizures and syndromes", Epilepsia, 43, pp.2~10 (2002)
- Clancy RR, "Prolonged electroencephalogram monitoring for seizures and their treatment", Clin Perinatol, 33, pp.649~665 (2006)
- Rennie JM, "Neonatal seizures and their treatment", Curr Opin Neurol, 16, pp.177~181 (2003)