극소저체중출생아에서 폐 공기낭종이 합병된 Paenibacillus 패혈증 1례
A Case of Paenibacillus-induced Sepsis Complicated with Pneumatocele in a Very Low Birth Weight Infant
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Paenibacillus는 그람 양성 간균으로서 자연에 존재하지만 사람에서의 감염은 드물다. 저자들은 재태주수 29주 5일, 출생체중 1,380 g의 극소저체중출생아에서 Paenibacillus에 의한 패혈증 및 폐 공기낭종을 경험하여 보고하는 바이다. 인공호흡기를 조기 발관하고 경장관 수유 및 총정맥영양을 병행하던 생후 13일의 환아가 갑작스러운 청색증 증상을 보였고 흉부방사선사진에서 늑막 흉수가 관찰되었으며 동시에 패혈증 증세를 동반하였다. 미생물검사에서 Paenibacillus가동정되었으며 정맥 항생제 투여로 증세는 호전되었다. 이후 흉부방사선사진에서 폐 공기낭종 의심 병변이 지속적으로관찰되어 시행한 흉부전산화단층촬영에서 공기낭종을 확진하였다.
Abstract
Paenibacillus spp. are gram-positive, rod-shaped, facultative anaerobic bacteria found in nature and rarely cause diseases in humans. We report our experience with Paenibacillus-induced sepsis complicated with pneumatocele in a very low birth weight male infant with a gestational age of 29 weeks and 5 days and a birth weight of 1,380 g, who was born by cesarean section with because of preterm labor and premature rupture of membrane. On day 12 after admission, the patient presented oxygen desaturation without apnea and fever. We identified pleural effusion on chest radiography and diagnosed pneumatocele on low-dose chest computed tomography. An empirical antibiotic was administered to treat the infection. The patient’s blood culture revealed gram-positive rods, and Paenibacillus spp. was identified using16s rRNA sequencing.
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