Sex Differences Associated With Hepatitis B Virus Surface Antigen Seropositivity Unwareness in Hepatitis B Virus Surface Antigen-positive Adults: 2007‐2012 Korea National Health and Nutrition Examination Survey
1
조회
0
다운로드
0
인용
0
참고문헌
키워드
초록
Objectives: To examine the sex-specific factors associated with being unaware of one’s hepatitis B virus surface antigen (HBsAg) seropositivity status in a large, HBsAg-positive population of Koreans. Methods: In total, 1197 subjects aged 19 years or older who were HBsAg-positive according to data from the 2007-2012 Korea National Health and Nutrition Examination Survey were included. Subjects were considered unaware of their HBsAg seropositivity status if they answered that they had no knowledge of being previously infected by the hepatitis B virus (HBV) or diagnosed with HBV hepatitis. Multivariate Poisson regression models with robust variance estimate were used to assess the significance of the variables using weighted frequencies. Results: The majority (77.8%) of HbsAg-positive Korean adults (females, 81.9%; males, 74.6%) were unaware of their HBsAg seropositivity status. We found that sex (female: prevalence ratio [PR] 1.19), household income (low: PR, 1.15), marital status (never married: PR, 1.18), self-rated health (moderate: PR, 1.14; good: PR, 1.12), and alcohol use (at least 2-3 times/wk: PR, 1.21) were associated with being unaware. In females, age (50 to 59 years: PR, 1.29; ≥70 years: PR, 1.30), household income (low: PR, 1.37; middle–low: PR, 1.24), and marital status (never married: PR, 1.33) were associated with being unaware. In males, self-rated health (moderate: PR, 1.14; good: PR, 1.21) and alcohol use (at least 2–3 times/wk: PR, 1.21) were associated with being unaware. Conclusions: Factors related to the socioeconomic status of females and the health-related behaviors of males were found to be associated with being unaware of one’s HBsAg seropositivity status.
Abstract
Objectives: To examine the sex-specific factors associated with being unaware of one’s hepatitis B virus surface antigen (HBsAg) seropositivity status in a large, HBsAg-positive population of Koreans. Methods: In total, 1197 subjects aged 19 years or older who were HBsAg-positive according to data from the 2007-2012 Korea National Health and Nutrition Examination Survey were included. Subjects were considered unaware of their HBsAg seropositivity status if they answered that they had no knowledge of being previously infected by the hepatitis B virus (HBV) or diagnosed with HBV hepatitis. Multivariate Poisson regression models with robust variance estimate were used to assess the significance of the variables using weighted frequencies. Results: The majority (77.8%) of HbsAg-positive Korean adults (females, 81.9%; males, 74.6%) were unaware of their HBsAg seropositivity status. We found that sex (female: prevalence ratio [PR] 1.19), household income (low: PR, 1.15), marital status (never married: PR, 1.18), self-rated health (moderate: PR, 1.14; good: PR, 1.12), and alcohol use (at least 2-3 times/wk: PR, 1.21) were associated with being unaware. In females, age (50 to 59 years: PR, 1.29; ≥70 years: PR, 1.30), household income (low: PR, 1.37; middle–low: PR, 1.24), and marital status (never married: PR, 1.33) were associated with being unaware. In males, self-rated health (moderate: PR, 1.14; good: PR, 1.21) and alcohol use (at least 2–3 times/wk: PR, 1.21) were associated with being unaware. Conclusions: Factors related to the socioeconomic status of females and the health-related behaviors of males were found to be associated with being unaware of one’s HBsAg seropositivity status.
참고문헌 (27)
- "GlOBOCAN 2012: estimated cancer incidence, mortality and prevalence worldwide in 2012"[URL]
- 정규원, "Cancer Statistics in Korea: Incidence, Mortality, Survival, and Prevalence in 2011", Cancer Research and Treatment, 46(2), pp.109~123 (2014), 대한암학회
- Donato F, "A meta-analysis of epidemiological studies on the combined effect of hepatitis B and C virus infections in causing hepatocellular carcinoma", Int J Cancer, 75(3), pp.347~354 (1998)
- Park SH, "Trends in the seroprevalence of hepatitis B surface antigen in the South Korean population", Int J Infect Dis, 16(9), pp.e669~e672 (2012)
- National Cancer Center, "Quality guidelines of liver cancer screening", National Cancer Center, 12~13 (2012)
- Noh DK, "Factors associated with attending the National Cancer Screening Program for liver cancer in Korea", Asian Pac J Cancer Prev, 13(2), pp.731~736 (2012)
- Park B, "Factors associated with compliance with recommendations for liver cancer screening in Korea: a nationwide survey in Korea", PLoS One, 8(6), pp.e68315~ (2013)
- Cho ER, "Factors associated with use of ultrasonography screening for hepatocellular carcinoma among hepatitis B or C carriers", Cancer Epidemiol, 34(6), pp.713~716 (2010)
- Park SH, "Hepatocellular carcinoma screening in a hepatitis B virus-infected Korean population", Dig Dis Sci, 57(12), pp.3258~3264 (2012)
- Kang M, "Factors associated with organized and opportunistic cancer screening: results of the Korea National Health and Nutrition Examination Survey (KNHANES) 2007-2011", Asian Pac J Cancer Prev, 15(7), pp.3279~3286 (2014)
- Wildman RP, "Appropriate body mass index and waist circumference cutoffs for categorization of overweight and central adiposity among Chinese adults", Am J Clin Nutr, 80(5), pp.1129~1136 (2004)
- WHO Expert Consultation, "Appropriate body-mass index for Asian populations and its implications for policy and intervention strategies", Lancet, 363(9403), pp.157~163 (2004)
- "BMI calculator"[URL]
- Spiegelman D, "Easy SAS calculations for risk or prevalence ratios and differences", Am J Epidemiol, 162(3), pp.199~200 (2005)
- Colvin HM, "Hepatitis and liver cancer: a national strategy for prevention and control of hepatitis B and C", pp.26~ (2010), National Academies Press
- Rotermann M, "Seroprevalence of hepatitis B and C virus infections: Results from the 2007 to 2009 and 2009 to 2011 Canadian Health Measures Survey", Health Rep, 24(11), pp.3~13 (2013)
- "Report on hepatitis patient self-help in Europe by the ELPA" (2010)[URL]
- Raimondo G, "Is there a downgrading in the alert about the hepatitis B virus infection in Italy?", Dig Liver Dis, 39(3), pp.257~261 (2007)
- Ippolito AM, "Unawareness of HBV infection among inpatients in a Southern Italian hospital", J Viral Hepat, 18(7), pp.e206~e211 (2011)
- Hartleb M, "Serological prevalence of hepatitis B virus and hepatitis C virus infection in the elderly population: Polish nationwide survey-PolSenior", Eur J Gastroenterol Hepatol, 24(11), pp.1288~1295 (2012)
- Hatzakis A, "The state of hepatitis B and C in Europe: report from the hepatitis B and C summit conference", J Viral Hepat, 18(Suppl 1), pp.1~16 (2011)
- Mota A, "Alcohol consumption among patients with hepatitis B infection in northern Portugal considering gender and hepatitis B virus genotype differences", Alcohol, 44(2), pp.149~156 (2010)
- 정낙소, "B형 간염바이러스, 음주, 그리고 B형 간염바이러스와 음주의 중복 원인에 의한 간경변증에서 간세포암종 발생에 관한 단면 비교연구", 대한소화기학회지, 49(6), pp.369~375 (2007), 대한소화기학회
- Korea Centers for Disease Control and Prevention, "Korea health statistics 2012: Korea National Health and Nutrition Examination Survey (KNHANESV-3)", Korea Centers for Disease Control and Prevention, 55~57 (2013)
- 정최경희, "Changes in Contribution of Causes of Death to Socioeconomic Mortality Inequalities in Korean Adults", 예방의학회지, 44(6), pp.249~259 (2011), 대한예방의학회
- Kim SR, "Epidemiology of hepatocellular carcinoma in Japan and Korea. A review", Oncology, 75(Suppl 1), pp.13~16 (2008)
- Chamot E, "Who gets screened, and where: a comparison of organised and opportunistic mammography screening in Geneva, Switzerland", Eur J Cancer, 43(3), pp.576~584 (2007)