Estimation of Utility Weights for Prostate-related Health States in Korea
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Objectives: Very limited previous research has investigated the utility weights of prostate-related diseases in the general population in Korea. The purpose of this study was to calculate the utility of prostate-related health states in the Korean general public using the standard gamble (SG) method. Methods: Seven health states for hypothetical prostate cancers, 1 for benign prostate hyperplasia, and 1 for erectile dysfunction were developed based on patient education material and previous publications. In total, 460 responses from the Korean general population were used to analyze the utility of prostate-related health states. Computer-assisted personal interviews were conducted, and utility values were measured using a visual analogue scale (VAS) and SG. Mean utility values were calculated for each prostate-related health state. Results: The mean utility values of prostate cancer derived from SG ranged from 0.281 (metastatic castration-refractory prostate cancer) to 0.779 (localized prostate cancer requiring prostatectomy). The utility value of benign prostate hyperplasia was 0.871, and that of erectile dysfunction was 0.812. The utility values obtained using the SG method in all conditions were higher than the values obtained by VAS. There were no significant demographic variables affecting utility values in multivariate analysis. Conclusions: Our findings might be useful for economic evaluation and utility calculation of screening and interventions for prostate-related conditions in the general population.
Abstract
Objectives: Very limited previous research has investigated the utility weights of prostate-related diseases in the general population in Korea. The purpose of this study was to calculate the utility of prostate-related health states in the Korean general public using the standard gamble (SG) method. Methods: Seven health states for hypothetical prostate cancers, 1 for benign prostate hyperplasia, and 1 for erectile dysfunction were developed based on patient education material and previous publications. In total, 460 responses from the Korean general population were used to analyze the utility of prostate-related health states. Computer-assisted personal interviews were conducted, and utility values were measured using a visual analogue scale (VAS) and SG. Mean utility values were calculated for each prostate-related health state. Results: The mean utility values of prostate cancer derived from SG ranged from 0.281 (metastatic castration-refractory prostate cancer) to 0.779 (localized prostate cancer requiring prostatectomy). The utility value of benign prostate hyperplasia was 0.871, and that of erectile dysfunction was 0.812. The utility values obtained using the SG method in all conditions were higher than the values obtained by VAS. There were no significant demographic variables affecting utility values in multivariate analysis. Conclusions: Our findings might be useful for economic evaluation and utility calculation of screening and interventions for prostate-related conditions in the general population.
참고문헌 (40)
- Jemal A, "Annual report to the nation on the status of cancer, 1975-2014, featuring survival", J Natl Cancer Inst, 109(9), pp.djx030~ (2017)
- Jemal A, "Cancer statistics, 2009", CA Cancer J Clin, 59(4), pp.225~249 (2009)
- Center MM, "International variation in prostate cancer incidence and mortality rates", Eur Urol, 61(6), pp.1079~1092 (2012)
- 원영주, "Geographical Variations and Trends in Major Cancer Incidences throughout Korea during 1999-2013", Cancer Research and Treatment, 50(4), pp.1281~1293 (2018), 대한암학회
- Kimura T, "Epidemiology of prostate cancer in Asian countries", Int J Urol, 25(6), pp.524~531 (2018)
- Cronin KA, "Annual report to the nation on the status of cancer, part I: national cancer statistics", Cancer, 124(13), pp.2785~2800 (2018)
- 정규원, "Cancer Statistics in Korea: Incidence, Mortality, Survival, and Prevalence in 2015", Cancer Research and Treatment, 50(2), pp.303~316 (2018), 대한암학회
- 이광식, "Economic Burden of Cancer in Korea during 2000-2010", Cancer Research and Treatment, 47(3), pp.387~398 (2015), 대한암학회[DOI]
- 이영주, "Nationwide incidence and treatment pattern of benign prostatic hyperplasia in Korea", Investigative and Clinical Urology, 57(6), pp.424~430 (2016), 대한비뇨의학회[DOI]
- Robert G, "Epidemiology of benign prostatic hyperplasia", Prog Urol, 28(15), pp.803~812 (2018)
- 박현준, "Urinary Tract Symptoms (LUTS) Secondary to Benign Prostatic Hyperplasia (BPH) and LUTS", BPH with Erectile Dysfunction in Asian Men: A Systematic Review Focusing on Tadalafil, 2013, pp.31(3), 193~207[DOI]
- Roehrborn CG, "Erectile dysfunction and lower urinary tract symptoms associated with benign prostatic hyperplasia(LUTS", BPH)combined responders to tadalafil after 12 weeks of treatment, 2016, pp.118(1), 153~160
- Glina S, "Lower urinary tract symptoms and erectile dysfunction are highly prevalent in ageing men", BJU Int, 97(4), pp.763~765 (2006)
- Morant S, "Increased sexual dysfunction in men with storage and voiding lower urinary tract symptoms", J Sex Med, 6(4), pp.1103~1110 (2009)
- Rosen RC, "Association of sexual dysfunction with lower urinary tract symptoms of BPH and BPH medical therapies : results from the BPH Registry", Urology, 73(3), pp.562~566 (2009)
- Dolan P, "Valuing health states : a comparison of methods", J Health Econ, 15(2), pp.209~231 (1996)
- Whitehead SJ, "Health outcomes in economic evaluation : the QALY and utilities", Br Med Bull, 96, pp.5~21 (2010)
- Drummond MF, "Methods for the economic evaluation of health care programmes", pp.147~173 (2005), Oxford University Press
- Torrance GW, "Social preferences for health states : an empirical evaluation of three measurement techniques", Socioecon Plann Sci, 10(3), pp.129~136 (1976)
- Wee HL, "Validity, feasibility and acceptability of time trade-offand standard gamble assessments in health valuation studies: a study in a multiethnic Asian population in Singapore", Value Health, 11(Suppl 1), pp.S3~S10 (2008)
- Kim SH, "Feasibility, comparability, and reliability of the standard gamble compared with the rating scale and time trade-offtechniques in Korean population", Qual Life Res, 26(12), pp.3387~3397 (2017)
- Bleichrodt H, "Standard gamble, time trade-offand rating scale: experimental results on the ranking properties of QALYs", J Health Econ, 16(2), pp.155~175 (1997)
- Torrance GW, "Measurement of health state utilities for economic appraisal", J Health Econ, 5(1), pp.1~30 (1986)
- Torrance GW, "Visual analog scales : do they have a role in the measurement of preferences for health states", Med Decis Making, 21(4), pp.329~334 (2001)
- Bremner KE, "A review and meta-analysis of prostate cancer utilities", Med Decis Making, 27(3), pp.288~298 (2007)
- Norman R, "International comparisons in valuing EQ-5D health states : a review and analysis", Value Health, 12(8), pp.1194~1200 (2009)
- Wittenberg E, "The effect of age, race and gender on preference scores for hypothetical health states", Qual Life Res, 15(4), pp.645~653 (2006)
- 김윤희, "한국에서 전립샘암 병기별․치료시기별 삶의 질", 보건경제와 정책연구, 19(2), pp.1~20 (2013), 한국보건경제정책학회
- Kim SH, "Estimation of health state utilities in breast cancer", Patient Prefer Adherence, 11, pp.531~536 (2017)
- "Appropriate perspectives for health care decisions" (2010)[URL]
- 조민우, "EQ-5D 건강상태에 대한 가치 평가 작업의 타당도와 신뢰도 평가: 컴퓨터 보조프로그램을 이용한 표준도박", Korean Journal of Health Promotion, 10(3), pp.105~112 (2010), 대한임상건강증진학회
- Krahn M, "Patient and community preferences for outcomes in prostate cancer : implications for clinical policy", Med Care, 41(1), pp.153~164 (2003)
- Gries KS, "Utility estimates of disease-specific health states in prostate cancer from three different perspectives", Appl Health Econ Health Policy, 15(3), pp.375~384 (2017)
- Torvinen S, "Health-related quality of life in prostate cancer", Acta Oncol, 52(6), pp.1094~1101 (2013)
- Bergius S, "Health-related quality of life among prostate cancer patients : real-life situation at the beginning of treatment", Scand J Urol, 51(1), pp.13~19 (2017)
- Krahn MD, "Utility and health-related quality of life in prostate cancer patients 12 months after radical prostatectomy or radiation therapy", Prostate Cancer Prostatic Dis, 12(4), pp.361~368 (2009)
- Smith KJ, "Quality-of-life utility values for erectile function and sildenafil treatment", Clin Drug Investig, 25(2), pp.99~105 (2005)
- Postulart D, "Response shift and adaptation in chronically ill patients", Med Decis Making, 20(2), pp.186~193 (2000)
- Pickard AS, "Psychometric comparison of the standard EQ-5D to a 5 level version in cancer patients", Med Care, 45(3), pp.259~263 (2007)
- Morimoto T, "Utilities measured by rating scale, time trade-off, and standard gamble: review and reference for health care professionals", J Epidemiol, 12(2), pp.160~178 (2002)
