Utilization of the Unlinked Case Proportion to Control COVID-19: A Focus on the Non-pharmaceutical Interventional Policies of the Korea and Japan
1
조회
0
다운로드
0
인용
0
참고문헌
키워드
초록
Objectives: Korea and Japan have managed the spread of coronavirus disease 2019 (COVID-19) using markedly different policies, referred to as the “3T” and “3C” strategies, respectively. This study examined these differences to assess the roles of active testing and contact tracing as non-pharmaceutical interventions (NPIs). We compared the proportion of unlinked cases (UCs) and test positivity rate (TPR) as indicators of tracing and testing capacities.Methods: We outlined the evolution of NPI policies and investigated temporal trends in their correlations with UCs, confirmed cases, and TPR prior to the Omicron peak. Spearman correlation coefficients were reported between the proportion of UCs, confirmed cases, and TPR. The Fisher <i>r</i>-to-<i>z</i> transformation was employed to examine the significance of differences between correlation coefficients.Results: The proportion of UCs was significantly correlated with confirmed cases (<i>r</i>=0.995, <i>p</i><0.001) and TPR (<i>r</i>=0.659, <i>p</i><0.001) in Korea and with confirmed cases (<i>r</i>=0.437, <i>p</i><0.001) and TPR (<i>r</i>=0.429, <i>p</i><0.001) in Japan. The Fisher <i>r</i>-to-<i>z</i> test revealed significant differences in correlation coefficients between the proportion of UCs and confirmed cases (<i>z</i>=16.07, <i>p</i><0.001) and between the proportion of UCs and TPR (<i>z</i>=2.12, <i>p</i>=0.034) in Korea and Japan.Conclusions: Higher UCs were associated with increases in confirmed cases and TPR, indicating the importance of combining testing and contact tracing in controlling COVID-19. The implementation of stricter policies led to stronger correlations between these indicators. The proportion of UCs and TPR effectively indicated the effectiveness of NPIs. If the proportion of UCs shows an upward trend, more testing and contact tracing may be required.
Abstract
Objectives: Korea and Japan have managed the spread of coronavirus disease 2019 (COVID-19) using markedly different policies, referred to as the “3T” and “3C” strategies, respectively. This study examined these differences to assess the roles of active testing and contact tracing as non-pharmaceutical interventions (NPIs). We compared the proportion of unlinked cases (UCs) and test positivity rate (TPR) as indicators of tracing and testing capacities.Methods: We outlined the evolution of NPI policies and investigated temporal trends in their correlations with UCs, confirmed cases, and TPR prior to the Omicron peak. Spearman correlation coefficients were reported between the proportion of UCs, confirmed cases, and TPR. The Fisher <i>r</i>-to-<i>z</i> transformation was employed to examine the significance of differences between correlation coefficients.Results: The proportion of UCs was significantly correlated with confirmed cases (<i>r</i>=0.995, <i>p</i><0.001) and TPR (<i>r</i>=0.659, <i>p</i><0.001) in Korea and with confirmed cases (<i>r</i>=0.437, <i>p</i><0.001) and TPR (<i>r</i>=0.429, <i>p</i><0.001) in Japan. The Fisher <i>r</i>-to-<i>z</i> test revealed significant differences in correlation coefficients between the proportion of UCs and confirmed cases (<i>z</i>=16.07, <i>p</i><0.001) and between the proportion of UCs and TPR (<i>z</i>=2.12, <i>p</i>=0.034) in Korea and Japan.Conclusions: Higher UCs were associated with increases in confirmed cases and TPR, indicating the importance of combining testing and contact tracing in controlling COVID-19. The implementation of stricter policies led to stronger correlations between these indicators. The proportion of UCs and TPR effectively indicated the effectiveness of NPIs. If the proportion of UCs shows an upward trend, more testing and contact tracing may be required.
참고문헌 (20)
- Flaxman S, "Estimating the effects of non-pharmaceutical interventions on COVID-19 in Europe", Nature, 584(7820), pp.257~261 (2020)
- Bedford J, "COVID-19 : towards controlling of a pandemic", Lancet, 395(10229), pp.1015~1018 (2020)
- Niazi MU, "Modeling and control of epidemics through testing policies", Annu Rev Control, 52, pp.554~572 (2021)
- Liu Y, "The impact of non-pharmaceutical interventions on SARS-CoV-2 transmission across 130 countries and territories", BMC Med, 19(1), pp.40~ (2021)
- Shokoohi M, "COVID-19 pandemic : what can the west learn from the east?", Int J Health Policy Manag, 9(10), pp.436~438 (2020)
- Zhao S, "COVID-19 pandemic, crisis responses and the changing world", pp.137~147 (2021), Springer
- Furuse Y, "Epidemiology of COVID-19 outbreak in Japan, from January-March 2020", Jpn J Infect Dis, 73(5), pp.391~393 (2020)
- "Japan’s cluster-based approach"[URL]
- Park Yoojin, "Application of Testing-Tracing-Treatment Strategy in Response to the COVID-19 Outbreak in Seoul, Korea", Journal of Korean Medical Science, 35(45), pp.1~9 (2020), 대한의학회[DOI]
- Wong NS, "Settings of virus exposure and their implications in the propagation of transmission networks in a COVID-19 outbreak", Lancet Reg Health West Pac, 4, pp.100052~ (2020)
- Chong KC, "Characterization of unlinked cases of COVID-19 and implications for contact tracing measures : retrospective analysis of surveillance data", JMIR Public Health Surveill, 7(11), pp.e30968~ (2021)
- Ryu S, "Transmission dynamics and control of two epidemic waves of SARS-CoV-2 in South Korea", BMC Infect Dis, 21(1), pp.485~ (2021)
- Jeon J, "Evolution of responses to COVID-19 and epidemiological characteristics in South Korea", Int J Environ Res Public Health, 19(7), pp.4056~ (2022)
- Hideo T, "Trends in the incidence of symptomatic COVID-19 during the first endemic wave in the Japanese population", J Natl Inst Public Health, 70(3), pp.315~322 (2021)
- "Coronavirus pandemic (COVID-19)" (2022)[URL]
- "Analysis of COVID-19 occurrence during the first-class legal infectious disease designation period (2020.1.20 to 2022.4.24.)"[URL]
- "COVID-19 case, testing and hospitalization data" (2022)[URL]
- Fisher RA, "Frequency distribution of the values of the correlation coefficient in samples from an indefinitely large population", Biometrika, 10(4), pp.507~521 (1915)
- "Regarding Japan’s COVID-19 crisis ‘Declaration of a state of emergency’ and ‘Priority measures such as prevention of spread’" (2021)[URL]
- Bradshaw WJ, "Bidirectional contact tracing could dramatically improve COVID-19 control", Nat Commun, 12(1), pp.232~ (2021)
