Majocchi 육아종 1예
A Case of Majocchi's Granuloma
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초록
Majocchi's granuloma is a well recognized but uncommon infection of dermal and subcutaneous tissue by fungal organisms usually limited to the superficial epidermis. The organism usually associated with Majocchi's granuloma is Trichophyton(T.) rubrum, however, other dermatophytes may be the causative agent. We presented a 74-year-old female who had a well defined erythematous nodular plaque on her right cheek for 1 month. Histopathologic findings was consistent with the Majocchi's granuloma, showing perifolliculitis and granulomatous inflammation in dermis. Many fungal elements were noted in the follicular keratin plug and giant cells in the granulomatous inflammation of the perifollicular dermis in the H & E stain. But no fungal hyphae was noted in horny layer of the epidermis and a culture for the fungus was failed. The cutaneous lesion treated with terbinafine (Lamisil®) 250 mg and lanoconazole cream daily with cured one month later.
Abstract
Majocchi's granuloma is a well recognized but uncommon infection of dermal and subcutaneous tissue by fungal organisms usually limited to the superficial epidermis. The organism usually associated with Majocchi's granuloma is Trichophyton(T.) rubrum, however, other dermatophytes may be the causative agent. We presented a 74-year-old female who had a well defined erythematous nodular plaque on her right cheek for 1 month. Histopathologic findings was consistent with the Majocchi's granuloma, showing perifolliculitis and granulomatous inflammation in dermis. Many fungal elements were noted in the follicular keratin plug and giant cells in the granulomatous inflammation of the perifollicular dermis in the H & E stain. But no fungal hyphae was noted in horny layer of the epidermis and a culture for the fungus was failed. The cutaneous lesion treated with terbinafine (Lamisil®) 250 mg and lanoconazole cream daily with cured one month later.
참고문헌 (8)
- "Trichophyton violaceum에 의한 육아종 1예", pp.304~307
- "Trichophyton rubrum에 의한 육아종 1예", 36, pp.136~ (1998)
- "피부사상균에 의한 육아종의 임상 및 조직학적 소견", pp.794~801
- "Trichophyton mentagrophytes에 의한 육아종 2예", 1, pp.113~117 (1996)
- "Pseudomycetoma due to Trichophyton schoenleinii occuring in two bro- thers", pp.102~106
- "Papular lesions in an immunocompromised patient", pp.1189~1190
- "New onset Majocchi's granuloma in two kidney transplant recipients under tacrolimus treatment", 38, pp.486~488 (1998)
- "Invasive Tricho- phyton rubrum infection in an immunocompromised host", pp.321~325
