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화상부위에 발생한 Majocchi 육아종

Majocchi's Granuloma Arising in Previous Burn Area

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초록

Majocchi's granuloma is deep dermatophyte infections rarely form ulceration, nodules and abscessesand usually occur in immunocompromised patients. Although progression of deep dermatophytosismay be induced by the use of topical or systemic steroids, immunosuppression may not be found insome cases. We report a case of Majocchi's granuloma arising in previous burn area, who had pruriticerythematous macules, patches and papules on the left forearm for 7 months. KOH mount was negative. Histopathological examination showed granulomatous reaction and numerous hyphae and spore in thedermis, and the organism was identified as Trichophyton rubrum on tissue culture. The patient was treatedwith 2 times of itraconazole pulse therapy and then terbinafine (250 mg/day) for 4 weeks, resulting inthe clearing of the lesion.

Abstract

Majocchi's granuloma is deep dermatophyte infections rarely form ulceration, nodules and abscessesand usually occur in immunocompromised patients. Although progression of deep dermatophytosismay be induced by the use of topical or systemic steroids, immunosuppression may not be found insome cases. We report a case of Majocchi's granuloma arising in previous burn area, who had pruriticerythematous macules, patches and papules on the left forearm for 7 months. KOH mount was negative. Histopathological examination showed granulomatous reaction and numerous hyphae and spore in thedermis, and the organism was identified as Trichophyton rubrum on tissue culture. The patient was treatedwith 2 times of itraconazole pulse therapy and then terbinafine (250 mg/day) for 4 weeks, resulting inthe clearing of the lesion.

참고문헌 (13)

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  10. Sequeira M, "New-onset Majocchi's granuloma in two kidney transplant recipients under tacrolimus treatment", J Am Acad Dermatol, 38, pp.486~488 (1998)
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