본문 바로가기
KERD
논문KCI 등재

Excess Deaths in Korea During the COVID-19 Pandemic: 2020-2022

0

조회

0

다운로드

0

인용

0

참고문헌

키워드

초록

Objectives: Excess deaths, an indicator that compares total mortality rates before and during a pandemic, offer a comprehensive view of the pandemic’s impact. However, discrepancies may arise from variations in estimating expected deaths. This study aims to compare excess deaths in Korea during the coronavirus disease 2019 pandemic using 3 methods and to analyze patterns using the most appropriate method.Methods: Expected deaths from 2020 to 2022 were estimated using mortality data from 2015-2019 as reference years. This estimation employed 3 approaches: (1) simple average, (2) age-adjusted average, and (3) age-adjusted linear regression. Excess deaths by age, gender, and cause of death were also presented.Results: The number of excess deaths varied depending on the estimation method used, reaching its highest point with the simple average and its lowest with the age-adjusted average. Age-adjusted linear regression, which accounts for both the aging population and declining mortality rates, was considered most appropriate. Using this model, excess deaths were estimated at 0.3% for 2020, 4.0% for 2021, and 20.7% for 2022. Excess deaths surged among individuals in their 20s throughout the pandemic, largely attributed to a rise in self-harm and suicide. Additionally, the results indicated sharp increases in deaths associated with “endocrine, nutritional, and metabolic diseases” and “symptoms, signs, and abnormal clinical and laboratory findings, not elsewhere classified.”Conclusions: Substantial variations in excess deaths were evident based on estimation method, with a notable increase in 2022. The heightened excess deaths among young adults and specific causes underscore key considerations for future pandemic responses.

Abstract

Objectives: Excess deaths, an indicator that compares total mortality rates before and during a pandemic, offer a comprehensive view of the pandemic’s impact. However, discrepancies may arise from variations in estimating expected deaths. This study aims to compare excess deaths in Korea during the coronavirus disease 2019 pandemic using 3 methods and to analyze patterns using the most appropriate method.Methods: Expected deaths from 2020 to 2022 were estimated using mortality data from 2015-2019 as reference years. This estimation employed 3 approaches: (1) simple average, (2) age-adjusted average, and (3) age-adjusted linear regression. Excess deaths by age, gender, and cause of death were also presented.Results: The number of excess deaths varied depending on the estimation method used, reaching its highest point with the simple average and its lowest with the age-adjusted average. Age-adjusted linear regression, which accounts for both the aging population and declining mortality rates, was considered most appropriate. Using this model, excess deaths were estimated at 0.3% for 2020, 4.0% for 2021, and 20.7% for 2022. Excess deaths surged among individuals in their 20s throughout the pandemic, largely attributed to a rise in self-harm and suicide. Additionally, the results indicated sharp increases in deaths associated with “endocrine, nutritional, and metabolic diseases” and “symptoms, signs, and abnormal clinical and laboratory findings, not elsewhere classified.”Conclusions: Substantial variations in excess deaths were evident based on estimation method, with a notable increase in 2022. The heightened excess deaths among young adults and specific causes underscore key considerations for future pandemic responses.

참고문헌 (36)

  1. Joffe AR, "COVID-19 : rethinking the lockdown groupthink", Front Public Health, 9, pp.625778~ (2021)[DOI]
  2. Ioannidis JP, "Over- and under-estimation of COVID-19 deaths", Eur J Epidemiol, 36(6), pp.581~588 (2021)[DOI]
  3. Ioannidis JP, "Flaws and uncertainties in pandemic global excess death calculations", Eur J Clin Invest, 53(8), pp.e14008~ (2023)[DOI]
  4. "Coronavirus pandemic (COVID-19)" (2020)[URL]
  5. Oh JH, "Excess deaths during COVID-19, how much more have increased?", KOSTAT Stat Plus 2023;Summer, 48~60 (2023)
  6. Msemburi W, "The WHO estimates of excess mortality associated with the COVID-19 pandemic", Nature, 613(7942), pp.130~137 (2023)[DOI]
  7. COVID-19 Excess Mortality Collaborators, "Estimating excess mortality due to the COVID-19 pandemic : a systematic analysis of COVID-19-related mortality, 2020-21", Lancet, 399(10334), pp.1513~1536 (2022)[DOI]
  8. Han C, "Excess mortality during the Coronavirus disease pandemic in Korea", BMC Public Health, 23(1), pp.1698~ (2023)[DOI]
  9. Kim JH, "Inequitable distribution of excess mortality during the COVID-19 pandemic in Korea, 2020", Epidemiol Health, 44, pp.e2022081~ (2022)[DOI]
  10. Shin MS, "Estimation of excess all-cause mortality during COVID-19 pandemic in Korea", J Korean Med Sci, 36(39), pp.e280~ (2021)[DOI]
  11. Levitt M, "Comparison of pandemic excess mortality in 2020-2021 across different empirical calculations", Environ Res, 213, pp.113754~ (2022)[DOI]
  12. Barbiellini Amidei C, "Estimating overall and cause-specific excess mortality during the COVID-19 pandemic : methodological approaches compared", Int J Environ Res Public Health, 20(11), pp.5941~ (2023)[DOI]
  13. "Causes of death statistics"[URL]
  14. "A pandemic primer on excess mortality statistics and their comparability across countries" (2020)[URL]
  15. Lim S, "How to cope with emerging viral diseases : lessons from South Korea’s strategy for COVID-19, and collateral damage to cardiometabolic health", Lancet Reg Health West Pac, 30, pp.100581~ (2023)[DOI]
  16. Bhattacharya J, "Understanding the exceptional pre-vaccination Era East Asian COVID-19 outcomes", Adv Biol Regul, 86, pp.100916~ (2022)[DOI]
  17. Sawano T, "Underestimation of COVID-19 cases in Japan : an analysis of RT-PCR testing for COVID-19 among 47 prefectures in Japan", QJM, 113(8), pp.551~555 (2020)[DOI]
  18. Park Y, "Application of testing-tracing-treatment strategy in response to the COVID-19 outbreak in Seoul, Korea", J Korean Med Sci, 35(45), pp.e396~ (2020)[DOI]
  19. Wang B, "Asymptomatic SARS-CoV-2 infection by age : a global systematic review and meta-analysis", Pediatr Infect Dis J, 42(3), pp.232~239 (2023)[DOI]
  20. Fukuda H, "SARS-CoV-2 seroprevalence in healthcare workers at a frontline hospital Tokyo", Sci Rep, 11(1), pp.8380~ (2021)[DOI]
  21. Tanaka H, "Impact of the COVID-19 pandemic on mortality trends in Japan : a reversal in 2021? A descriptive analysis of national mortality data, 1995-2021", BMJ Open, 13(8), pp.e071785~ (2023)[DOI]
  22. Doshi P, "Covid-19 : do many people have pre-existing immunity?", BMJ, 370, pp.m3563~ (2020)[DOI]
  23. Murray SM, "The impact of pre-existing cross-reactive immunity on SARS-CoV-2 infection and vaccine responses", Nat Rev Immunol, 23(5), pp.304~316 (2023)[DOI]
  24. Souilmi Y, "An ancient viral epidemic involving host coronavirus interacting genes more than 20, 000 years ago in East Asia", Curr Biol, 31(16), pp.3504~3514 (2021)[DOI]
  25. Sánchez CA, "A strategy to assess spillover risk of bat SARS-related coronaviruses in Southeast Asia", Nat Commun, 13(1), pp.4380~ (2022)[DOI]
  26. Nguyen TT, "Pre-existing cross-reactive neutralizing activity against SARS-CoV-2 and seasonal coronaviruses prior to the COVID-19 pandemic(2014-2019)with limited immunity against recent emerging SARS-CoV-2 variants, Vietnam", Int J Infect Dis, 139, pp.109~117 (2024)[DOI]
  27. Pezzullo AM, "Age-stratified infection fatality rate of COVID-19 in the non-elderly population", Environ Res, 216(Pt 3), pp.114655~ (2023)[DOI]
  28. Ryu S, "Trends in suicide deaths before and after the COVID-19 outbreak in Korea", PLoS One, 17(9), pp.e0273637~ (2022)[DOI]
  29. Kim S, "Trends in emergency department visits for suicide attempts before and during the COVID-19 pandemic in Korea : a nationwide study, 2016-2021", J Affect Disord, 331, pp.184~191 (2023)[DOI]
  30. Sakamoto H, "Assessment of suicide in Japan during the COVID-19 pandemic vs previous years", JAMA Netw Open, 4(2), pp.e2037378~ (2021)[DOI]
  31. Bridge JA, "Youth suicide during the first year of the COVID-19 pandemic", Pediatrics, 151(3), pp.e2022058375~ (2023)[DOI]
  32. Sayed AA, "The effects of COVID-19 on the mental health of children and adolescents : a review", Cureus, 16(3), pp.e56473~ (2024)[DOI]
  33. Woo HG, "National trends in sadness, suicidality, and COVID-19 pandemic-related risk factors among South Korean adolescents from 2005 to 2021", JAMA Netw Open, 6(5), pp.e2314838~ (2023)[DOI]
  34. Giuntella O, "Lifestyle and mental health disruptions during COVID-19", Proc Natl Acad Sci U S A, 118(9), pp.e2016632118~ (2021)[DOI]
  35. Nomura S, "Impact of the COVID-19 pandemic on cancer death locations in Japan : an analysis of excess mortality through February 2023", J Epidemiol, 34(7), pp.349~355 (2024)[DOI]
  36. Schöley J, "Conflicting COVID-19 excess mortality estimates", Lancet, 401(10375), pp.431~432 (2023)[DOI]

이 간행물의 다른 논문 (9건)