Cariogenic Activity in Saliva of Korean Head and Neck Cancer Patients
2
조회
0
다운로드
0
인용
0
참고문헌
키워드
초록
The purpose of this study is to evaluate salivary flow rate,salivary pH, and cariogenic activity using unstimulatedsaliva of the head and neck cancer patients. Twenty threecancer patients (19 males, 4 females) who had undergonechemotherapy and radiation therapy and twenty four healthyvolunteers (14 males, 10 females) as a control were included. Salivary flow rate, salivary pH, and cariogenic activity usingunstimulated saliva were examined. Compared to saliva ofthe control group, salivary flow rate (p<0.001) and salivarypH (p<0.001) were significantly lower in head and neckcancer patients. The colony counts of Lactobacilli was higherin head and neck cancer patients (p<0.05) than in controlgroup. These salivary factors and cariogenic activity canincrease the prevalence of dental caries in head and neckcancer patients.
Abstract
The purpose of this study is to evaluate salivary flow rate,salivary pH, and cariogenic activity using unstimulatedsaliva of the head and neck cancer patients. Twenty threecancer patients (19 males, 4 females) who had undergonechemotherapy and radiation therapy and twenty four healthyvolunteers (14 males, 10 females) as a control were included. Salivary flow rate, salivary pH, and cariogenic activity usingunstimulated saliva were examined. Compared to saliva ofthe control group, salivary flow rate (p<0.001) and salivarypH (p<0.001) were significantly lower in head and neckcancer patients. The colony counts of Lactobacilli was higherin head and neck cancer patients (p<0.05) than in controlgroup. These salivary factors and cariogenic activity canincrease the prevalence of dental caries in head and neckcancer patients.
참고문헌 (29)
- Hopkins J, "Genetic polymorphisms and head and neck cancer outcomes : a review", Cancer Epidemiol Biomarkers Prev, 17, pp.490~499 (2008)
- Hashibe M1, "Alcohol drinking in never users of tobacco, cigarette smoking in never drinkers, and the risk of head and neck cancer : pooled analysis in the International Head and Neck Cancer Epidemiology Consortium", J Natl Cancer Inst, 99, pp.777~789 (2007)
- Warnakulasuriya S, "Global epidemiology of oral and oropharyngeal cancer", Oral Oncol, 45, pp.309~316 (2009)
- 최용금, "1990년대 이후의 한국인 치아우식증 외래환자 수 변화 -1990~2008년 환자조사 자료에 근거하여-", 한국치위생학회지, 11(4), pp.489~497 (2011), 한국치위생학회
- Dimery IW, "Overview of combined modality therapies for head and neck cancer", J Natl Cancer Inst, 85, pp.95~111 (1993)
- Kaban LB, "Complications in oral and maxillofacial surgery", pp.179~ (1997), WB Saunders
- 김종배, "주요 악성종양 입원환자에서 구강합병증 관리에 관한 임상적 연구", Maxillofacial Plastic Reconstructive Surgery, 26(1), pp.53~60 (2004), 대한악안면성형재건외과학회
- Silverman S Jr, "Oral cancer : complications of therapy", Oral Surg Oral Med Oral Pathol Oral Radiol Endod, 88, pp.122~126 (1999)
- Epstein JB, "The relationship among fluoride, cariogenic, oral flora, and salivary flow rate during radiation therapy", Oral Surg Oral Med Oral Pathol Oral Radiol Endod, 86, pp.286~292 (1998)
- 허수경, "소아암 환자에서 방사선 치료 후 영구치 치근발육장애 : 증례보고", 대한소아치과학회지, 35(1), pp.144~150 (2008), 대한소아치과학회
- Becks H, "Human saliva: Ⅸ. the effect of activation on salivary flow", J Dent Res, 18, pp.447~456 (1939)
- Navazesh M, "Method for collecting saliva", Ann N Y Acad Sci, 20, pp.694~727 (1993)
- Selwitz RH, "Dental caries", Lancet, 369, pp.51~59 (2007)
- Newbrun E, "Cariology", pp.289~299 (1989), Quintessence Publish
- Eneroth CM, "Pre-irradiation qualities of a parotid gland in predicting the grade of functional disturbance by radiotherapy", Acta Otolaryngol, 7, pp.436~444 (1972)
- Kashima HK, "Post-irradiation sialoadenitis ; a study of the clinical features-histopathologic change and serum enzyme variations following irradiation of human salivary glands", Am J Roentgenol Radium Ther Nucl Med, 94, pp.271~291 (1965)
- Dawes C, "Estimates, from salivary analyses, of the turnover time of the oral mucosal epithelium in humans and the number of bacteria in an edentulous mouth", Arch Oral Biol, 48, pp.329~336 (2003)
- Kaur A, "Evaluation of non-microbial salivary caries activity parameters and salivary biochemical indicators in predicting dental caries", J Indian Soc Pedod Prev Dent, 30, pp.212~217 (2012)
- Leone CW, "Physical and chemical aspects of saliva as indicators of risk for dental caries in human", J Dent Educ, 65, pp.1054~1064 (2001)
- Miller CS, "Current developments in salivary diagnostics", Biomark Med, 4, pp.171~189 (2010)
- Tukia-Kulmala H, "Intra-and inter-individual variation in salivary flow rate, buffer effect, lactobacilli, and mutans streptococci among 11-to 12-year-old schoolchildren", Acta Odont Scand, 51, pp.31~37 (1993)
- Vissink A, "Oral sequelae of head and neck radiotherapy", Crit Rev Oral Biol Med, 14, pp.199~212 (2003)
- 나희삼, "Oral Microbiota Comparison between Healthy volunteers, Periodontitis patients and Oral cancer patients", International Journal of Oral Biology, 38(4), pp.181~188 (2013), 대한구강생물학회
- Greenstein G, "Bacterial transmission in periodontal diseases : a critical review", J Periodontol, 68, pp.421~431 (1997)
- Lee JH, "The changes of salivary microorganism composition after therapeutic radiation for oral cancer patients", J of Korean Acad Oral Maxillofac Surg, 26, pp.18~23 (2000)
- Eliasson L, "Dental plaque pH and micro-organisms during hyposalivation", J Dent Res, 85, pp.334~338 (2006)
- Almståhl A, "Lactobacillus species in supragingival plaque in subjects with hyposalivation", Arch Oral Biol, 55, pp.255~259 (2010)
- Aas JA, "Bacteria of dental caries in primary and permanent teeth in children and young adults", J Clin Microbiol, 46, pp.1407~1417 (2008)
- Tong HC, "Non-mutans streptococci in patients receiving radiotherapy in the head and neck area", Caries Res, 37, pp.261~266 (2003)