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Antimicrobial Effects of Oleanolic Acid, Ursolic Acid, and Sophoraflavanone G against Enterococcus faecalis and Propionibacterium acnes

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초록

The aim of this study was to investigate antimicrobialeffect of oleanolic acid (OA), ursolic acid (UA), andsophoraflavanone G against Enterococcus faecalis andPropionibacterium acnes, which are the major causativebacteria of endodontic infections. The antimicrobial activitywas evaluated by the minimal inhibitory concentration(MIC). The data showed that the OA, UA, andsophoraflavanone G had antimicrobial effect on all thestrains use in the study with 16-64 μg/ml, 8-64 μg/ml, and 1-8μg/ml of MIC values, respectively. These results indicate thatOA, UA, and sophoraflavanone G could be useful in thedevelopment of antiseptic solution for washing the root canal in endodontic treatments.

Abstract

The aim of this study was to investigate antimicrobialeffect of oleanolic acid (OA), ursolic acid (UA), andsophoraflavanone G against Enterococcus faecalis andPropionibacterium acnes, which are the major causativebacteria of endodontic infections. The antimicrobial activitywas evaluated by the minimal inhibitory concentration(MIC). The data showed that the OA, UA, andsophoraflavanone G had antimicrobial effect on all thestrains use in the study with 16-64 μg/ml, 8-64 μg/ml, and 1-8μg/ml of MIC values, respectively. These results indicate thatOA, UA, and sophoraflavanone G could be useful in thedevelopment of antiseptic solution for washing the root canal in endodontic treatments.

참고문헌 (36)

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