A systematic review and meta-analysis of the genetic characterization of human echinococcosis in Iran, an endemic country
2
조회
0
다운로드
1
인용
0
참고문헌
키워드
초록
Human echinococcosis is an infectious disease caused by tapeworms belonging to the species Echinococcus. This parasite has a worldwide distribution and is considered a neglected tropical disease by the World Health Organization. Due to the diversity of Echinococcus spp. hosts, as well as variation in geographical, climatic, and socio-ethnic conditions, the question of the strains or genotypes of Echinococcus spp. that are involved in human infections is important. The aim of this study was to provide a summary of the available data on genotypes of Echinococcus obtained from the Iranian population. Four international databases (PubMed, Scopus, Science Direct, and Web of Science) and 4 Persian databases (Magiran, Scientific Information Database, Iran Medex, and IranDoc) were searched for cross-sectional studies that reported the genotypes of Echinococcus spp. in human echinococcosis cases using molecular methods in Iran through July 2018. The Newcastle-Ottawa Scale was used to assess the quality of the selected studies. A total of 559 cases of human cystic echinococcosis were reported in the 21 included articles. The majority of cases belonged to genotype G1 (89.2%; 95% confidence interval [CI], 80.1 to 95.8), genotype G6 (8.2%; 95% CI, 2.8 to 15.9), and genotype G3 (2.3%; 95% CI, 1.1 to 3.9). Since genotype G1 of Echinococcus appears to be the most prevalent genotype affecting humans in Iran, disease control initiatives aimed at sheep intermediate hosts may be the most beneficial. In addition, educational programs and serological screening in individuals may help reduce the national impact of the disease.
Abstract
Human echinococcosis is an infectious disease caused by tapeworms belonging to the species Echinococcus. This parasite has a worldwide distribution and is considered a neglected tropical disease by the World Health Organization. Due to the diversity of Echinococcus spp. hosts, as well as variation in geographical, climatic, and socio-ethnic conditions, the question of the strains or genotypes of Echinococcus spp. that are involved in human infections is important. The aim of this study was to provide a summary of the available data on genotypes of Echinococcus obtained from the Iranian population. Four international databases (PubMed, Scopus, Science Direct, and Web of Science) and 4 Persian databases (Magiran, Scientific Information Database, Iran Medex, and IranDoc) were searched for cross-sectional studies that reported the genotypes of Echinococcus spp. in human echinococcosis cases using molecular methods in Iran through July 2018. The Newcastle-Ottawa Scale was used to assess the quality of the selected studies. A total of 559 cases of human cystic echinococcosis were reported in the 21 included articles. The majority of cases belonged to genotype G1 (89.2%; 95% confidence interval [CI], 80.1 to 95.8), genotype G6 (8.2%; 95% CI, 2.8 to 15.9), and genotype G3 (2.3%; 95% CI, 1.1 to 3.9). Since genotype G1 of Echinococcus appears to be the most prevalent genotype affecting humans in Iran, disease control initiatives aimed at sheep intermediate hosts may be the most beneficial. In addition, educational programs and serological screening in individuals may help reduce the national impact of the disease.
참고문헌 (52)
- Ito A, "The echinococcoses in Asia : the present situation", Acta Trop, 176, pp.11~21 (2017)
- Fasihi Harandi M, "The monetary burden of cystic echinococcosis in Iran", PLoS Negl Trop Dis, 6, pp.e1915~ (2012)
- Otero-Abad B, "A systematic review of the epidemiology of echinococcosis in domestic and wild animals", PLoS Negl Trop Dis, 7, pp.e2249~ (2013)
- Cringoli G, "Geo-referencing livestock farms as tool for studying cystic echinococcosis epidemiology in cattle and water buffaloes from southern Italy", Geospat Health, 2, pp.105~111 (2007)
- Kebede N, "Hydatidosis of slaughtered animals in Bahir Dar Abattoir, Northwestern Ethiopia", Trop Anim Health Prod, 41, pp.43~50 (2009)
- Nakao M, "Phylogenetic systematics of the genus Echinococcus(Cestoda : Taeniidae)", Int J Parasitol, 43, pp.1017~1029 (2013)
- Thompson RC, "Biology and systematics of Echinococcus", Adv Parasitol, 95, pp.65~109 (2017)
- "WHO/OIE manual on echinococcosis in humans and animals: a public health problem of global concern" (2001)[URL]
- Cerda JR, "Tapeworms in North America", Emerg Infect Dis, 24, pp.230~235 (2018)
- Rokni MB, "Echinococcosis", hydatidosis in Iran, 2009, pp.4, 1~16
- Odongo DO, "Prevalence and genotyping of Echinococcus granulosus in sheep in Narok County, Kenya", Parasitol Res, 117, pp.2065~2073 (2018)
- Nakao M, "A molecular phylogeny of the genus Echinococcus inferred from complete mitochondrial genomes", Parasitology, 134, pp.713~722 (2007)
- Craig PS, "Prevention and control of cystic echinococcosis", Lancet Infect Dis, 7, pp.385~394 (2007)
- Anvari D, "Epidemiology and molecular prevalence of toxoplasma gondii in cattle slaughtered in Zahedan and Zabol Districts, South East of Iran", Iran J Parasitol, 13, pp.114~119 (2018)
- Gholami Sh, "Molecular characterization of Echinococcus granulosus from hydatid cysts isolated from human and animals in Golestan Province, North of Iran", Iran J Parasitol, 7, pp.8~16 (2012)
- Shamsi M, "Determination of genotype isolates of human and sheep hydatid cyst in Ilam", J Ilam Univ Med Sci, 23, pp.111~119 (2015)[DOI]
- Sharbatkhori M, "Echinococcus granulosus sensu lato genotypes in domestic livestock and humans in Golestan Province, Iran", Rev Inst Med Trop Sao Paulo, 58, pp.38~ (2016)
- Nikmanesh B, "Genotyping of Echinococcus granulosus isolates from human clinical samples based on sequencing of mitochondrial genes in Iran, Tehran", Iran J Parasitol, 9, pp.20~27 (2014)
- Arbabi M, "Molecular and morphological characterizations of Echinococcus granulosus from human and animal isolates in Kashan, Markazi Province, Iran", Iran J Parasitol, 12, pp.177~187 (2017)
- Rostami S, "Genetic characterization of Echinococcus granulosus from a large number of formalin-fixed, paraffin-embedded tissue samples of human isolates in Iran", Am J Trop Med Hyg, 92, pp.588~594 (2015)
- Shahnazi M, "Molecular characterization of human and animal Echinococcus granulosus isolates in Isfahan, Iran", Acta Trop, 117, pp.47~50 (2011)
- Dousti M, "Genotyping of hydatid cyst isolated from human and domestic animals in Ilam Province, Western Iran using PCR-RFLP", Iran J Parasitol, 8, pp.47~52 (2013)
- Kheirandish F, "Genetic characterization of human-derived hydatid cysts of Echinococcus granulosus in Lorestan Province, Western Iran", Trop Biomed, 34, pp.863~869 (2017)
- Jafarzadeh F, "Molecular and phylogenetic analysis of human hydatid cysts", JNKUMS, 9, pp.15~19 (2018)[DOI]
- Harandi MF, "Molecular and morphological characterization of Echinococcus granulosus of human and animal origin in Iran", Parasitology, 125, pp.367~373 (2002)
- Kia EB, "Genotype identification of human cystic echinococcosis in Isfahan, central Iran", Parasitol Res, 107, pp.757~760 (2010)
- Pezeshki A, "Genotyping of Echinococcus granulosus from domestic animals and humans from Ardabil Province, Northwest Iran", J Helminthol, 87, pp.387~391 (2013)
- Sadjjadi SM, "Evidence that the Echinococcus granulosus G6 genotype has an affinity for the brain in humans", Int J Parasitol, 43, pp.875~877 (2013)
- Gorgani-Firouzjaee T, "Genotype characterization of livestock and human cystic echinococcosis in Mazandaran Province, Iran", J Helminthol, 93, pp.255~259 (2018)
- Khademvatan S, "Molecular characterization of livestock and human isolates of Echinococcus granulosus from south-west Iran", J Helminthol, 87, pp.240~244 (2013)
- Karamian M, "Heterogenity of Echinococcus canadensis genotype 6-the main causative agent of cystic echinococcosis in Birjand, Eastern Iran", Vet Parasitol, 245, pp.78~85 (2017)
- Vahedi A, "Genotypic characteristics of hydatid cysts isolated from humans in East Azerbaijan Province(2011-2013)", J Anal Res Clin Med, 2, pp.152~157 (2014)
- Farhadi M, "Genetic characterization of livestock and human hydatid cyst isolates from northwest Iran, using the mitochondrial cox1 gene sequence", Parasitol Res, 114, pp.4363~4370 (2015)
- Jafari R, "Genetic characterization of Echinococcus granulosus strains isolated from humans based on nad1 and cox1 gene analysis in Isfahan, central Iran", J Helminthol, 92, pp.696~702 (2018)
- Spotin A, "Designing and conducting in silico analysis for identifying of Echinococcus spp. with discrimination of novel haplotypes: an approach to better understanding of parasite taxonomic", Parasitol Res, 114, pp.1503~1509 (2015)
- 배종면, "A suggestion for quality assessment in systematic reviews of observational studies in nutritional epidemiology", Epidemiology and Health, 38, pp.1~6 (2016), 한국역학회[DOI]
- Anvari D, "Seroprevalence of Toxoplasma gondii infection in cancer patients : a systematic review and meta-analysis", Microb Pathog, 129, pp.30~42 (2019)
- Saberi R, "Is Toxoplasma gondii playing a positive role in multiple sclerosis risk? A systematic review and meta-analysis", J Neuroimmunol, 322, pp.57~62 (2018)
- Hosseininejad Z, "Toxoplasmosis seroprevalence in rheumatoid arthritis patients: a systematic review and meta-analysis", PLoS Negl Trop Dis, 12, pp.e0006545~ (2018)
- Rahimi MT, "Application of multiplex PCR for the simultaneous detection of Taenia spp. from domestic dogs in the north of Iran", Helminthologia, 53, pp.285~289 (2016)
- Sadjjadi SM, "Present situation of echinococcosis in the Middle East and Arabic North Africa", Parasitol Int, 55(Suppl), pp.S197~S202 (2006)
- Schneider R, "Development of a new PCR protocol for the detection of species and genotypes(strains)of Echinococcus in formalin-fixed, paraffin-embedded tissues", Int J Parasitol, 38, pp.1065~1071 (2008)
- Khademvatan S, "Echinococcus granulosus genotypes in Iran : a systematic review", J Helminthol, 93, pp.131~138 (2019)
- Cucher MA, "Cystic echinococcosis in South America : systematic review of species and genotypes of Echinococcus granulosus sensu lato in humans and natural domestic hosts", Trop Med Int Health, 21, pp.166~175 (2016)
- Galeh TM, "The seroprevalence rate and population genetic structure of human cystic echinococcosis in the Middle East : a systematic review and meta-analysis", Int J Surg, 51, pp.39~48 (2018)
- Yildiz K, "Prevalence of hydatidosis and fertility of hydatid cysts in sheep in Kirikkale, Turkey", Acta Vet Hung, 51, pp.181~187 (2003)
- Alvarez Rojas CA, "Echinococcus granulosus sensu lato genotypes infecting humans-review of current knowledge", Int J Parasitol, 44, pp.9~18 (2014)
- Elham M, "Epidemiological study of hydatidosis in the dromedaries (Camelus dromedarius) of different regions of Iran", Asian Pac J Trop Biomed, 4, pp.S148~S151 (2014)
- Sharma M, "Molecular characterization of Echinococcus granulosus cysts in north Indian patients: identification of G1, G3, G5 and G6 genotypes", PLoS Negl Trop Dis, 7, pp.e2262~ (2013)
- Casulli A, "Genetic variability of Echinococcus granulosus sensu stricto in Europe inferred by mitochondrial DNA sequences", Infect Genet Evol, 12, pp.377~383 (2012)
- Sharbatkhori M, "Sequence analysis of cox1 and nad1 genes in Echinococcus granulosus G3 genotype in camels(Camelus dromedarius)from central Iran", Parasitol Res, 108, pp.521~527 (2011)
- Parsa F, "Genotyping Echinococcus granulosus from dogs from Western Iran", Exp Parasitol, 132, pp.308~312 (2012)
