Fibrinogen-Based Collagen Fleece Graft Myringoplasty for Traumatic Tympanic Membrane Perforation
2
조회
0
다운로드
0
인용
0
참고문헌
키워드
초록
Background and Objectives: The aim of this study was to investigate how fibrinogenbased collagen fleece (Tachocomb®) graft myringoplasty (FCGM), performed under microscopic guidance, improves both hearing and tympanic membrane tissue repair in patients with traumatic tympanic membrane perforation (TMP). Subjects and Methods: Between August 2009 and March 2015, a total of 52 patients with traumatic TMP visited the department of otorhinolaryngology at a secondary medical center. Twenty-nine of these underwent FCGM under microscopic guidance in our outpatient clinic. For each patient, we recorded the location and size of the perforation, the time elapsed from the onset of TMP until the myringoplasty, and the hearing level both before and after myringoplasty. Results: The TMP closed completely in all cases (29 of 29 patients). After myringoplasty, the postoperative airbone gap (ABG) differed significantly from the preoperative ABG. Three of the 29 patients (10.3%) experienced complications. Specifically, 2 presented with otorrhea after FCGM, but conservative management led to improvement without recurrence of perforation. One patient showed delayed facial palsy 1 week after the procedure. The condition of this patient also improved and the palsy was not permanent. Conclusions: FCGM may be an effective treatment option in case of traumatic TMP. The procedure requires no hospitalization, and can be used to avoid traditional tympanoplasty.
Abstract
Background and Objectives: The aim of this study was to investigate how fibrinogenbased collagen fleece (Tachocomb®) graft myringoplasty (FCGM), performed under microscopic guidance, improves both hearing and tympanic membrane tissue repair in patients with traumatic tympanic membrane perforation (TMP). Subjects and Methods: Between August 2009 and March 2015, a total of 52 patients with traumatic TMP visited the department of otorhinolaryngology at a secondary medical center. Twenty-nine of these underwent FCGM under microscopic guidance in our outpatient clinic. For each patient, we recorded the location and size of the perforation, the time elapsed from the onset of TMP until the myringoplasty, and the hearing level both before and after myringoplasty. Results: The TMP closed completely in all cases (29 of 29 patients). After myringoplasty, the postoperative airbone gap (ABG) differed significantly from the preoperative ABG. Three of the 29 patients (10.3%) experienced complications. Specifically, 2 presented with otorrhea after FCGM, but conservative management led to improvement without recurrence of perforation. One patient showed delayed facial palsy 1 week after the procedure. The condition of this patient also improved and the palsy was not permanent. Conclusions: FCGM may be an effective treatment option in case of traumatic TMP. The procedure requires no hospitalization, and can be used to avoid traditional tympanoplasty.
참고문헌 (20)
- Villar-Fernandez MA, "Outlook for tissue engineering of the tympanic membrane", Audiol Res, 5, pp.117~ (2015)
- Lindeman P, "Acute traumatic tympanic membrane perforations. Cover or observe?", Arch Otolaryngol Head Neck Surg, 113, pp.1285~1287 (1987)
- Simsek G, "Early paper patching versus observation in patients with traumatic eardrum perforations: comparisons of anatomical and functional outcomes", J Craniofac Surg, 25, pp.2030~2032 (2014)
- Kim J, "Comparison of methods for the repair of acute tympanic membrane perforations:Silk patch vs. paper patch", Wound Repair Regen, 18, pp.132~138 (2010)
- Rickenbacher A, "Efficacy of TachoSil a fibrin-based haemostat in different fields of surgery--a systematic review", Expert Opin Biol Ther, 9, pp.897~907 (2009)
- Knutsson J, "Collagen type distribution in the healthy human tympanic membrane", Otol Neurotol, 30, pp.1225~1229 (2009)
- Stenfeldt K, "The collagen structure of the tympanic membrane: collagen types I, II, and III in the healthy tympanic membrane, during healing of a perforation, and during infection", Arch Otolaryngol Head Neck Surg, 132, pp.293~298 (2006)
- Lim DJ, "Structure and function of the tympanic membrane: a review", Acta Otorhinolaryngol Belg, 49, pp.101~115 (1995)
- Shambaugh GE, "Surgery of the ear", pp.249~265 (1967), WB Sunders
- Glasscock ME, "Glasscock-Shambaugh Surgery of the Ear", pp.400~420 (2003), BC Decker Inc
- Getman V, "Fleece bound sealing prevents pleural adhesions", Interact Cardiovasc Thorac Surg, 5, pp.243~246 (2006)
- Hempel JM, "Traumatic tympanic membrane perforations: clinical and audiometric findings in 198 patients", Otol Neurotol, 33, pp.1357~1362 (2012)
- Kristensen S, "Spontaneous healing of traumatic tympanic membrane perforations in man: a century of experience", J Laryngol Otol, 106, pp.1037~1050 (1992)
- Chun SH, "A clinical study of traumatic tympanic membrane perforation", Korean J Otolaryngol-Head Neck Surg, 42, pp.437~441 (1999)
- Lee SH, "Paper-patch myringoplasty with CO2 laser for chronic TM perforation", Eur Arch Otorhinolaryngol, 265, pp.1161~1164 (2008)
- Hakuba N, "Basic fibroblast growth factor combined with atelocollagen for closing chronic tympanic membrane perforations in 87 patients", Otol Neurotol, 31, pp.118~121 (2010)
- Lou ZC, "A randomised controlled trial comparing spontaneous healing, gelfoam patching and edge-approximation plus gelfoam patching in traumatic tympanic membrane perforation with inverted or everted edges", Clin Otolaryngol, 36, pp.221~226 (2011)
- Saliba I, "Hyaluronic acid fat graft myringoplasty: a minimally invasive technique", Laryngoscope, 121, pp.375~380 (2011)
- Araujo MM, "Anatomical and functional evaluation of tympanoplasty using a transitory natural latex biomembrane implant from the rubber tree Hevea brasiliensis", Acta Cir Bras, 27, pp.566~571 (2012)
- Jun HJ, "A new patch material for tympanic membrane perforation by trauma: the membrane of a hen egg shell", Acta Otolaryngol, 134, pp.250~254 (2014)