Single Dose Topical Application of Clotrimazole for the Treatment of Otomycosis: Is This Enough?
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Background and Objectives: To determine the efficacy of filling the external auditory meatuswith 1% clotrimazole at a single visit for the treatment of otomycosis. Subjects andMethods: This prospective study included 40 patients who were referred to our clinic withcomplaints of ear itching, pain, and fullness, and were diagnosed with unilateral otomycosis. After cleaning the mycotic hyphae from the external auditory meatus, the ear canal was filledwith 1% clotrimazole, using an intravenous catheter and syringe. The patients received follow-up examinations on post-treatment days 7, 15, and 45. Results: The follow-up otomicroscopicexaminations revealed that 95% of the ear canals were entirely clean and that allsymptoms had resolved. The post-treatment scores of pain, aural fullness and itching weresignificantly lower than the pre-treatment scores (p<0.01). Conclusions: Filling the externalauditory meatus with 1% clotrimazole at a single visit is an easy, efficient, and cost-effectivetreatment for otomycosis. Additionally, high patient compliance makes this treatment superiorto long-term topical therapy.
Abstract
Background and Objectives: To determine the efficacy of filling the external auditory meatuswith 1% clotrimazole at a single visit for the treatment of otomycosis. Subjects andMethods: This prospective study included 40 patients who were referred to our clinic withcomplaints of ear itching, pain, and fullness, and were diagnosed with unilateral otomycosis. After cleaning the mycotic hyphae from the external auditory meatus, the ear canal was filledwith 1% clotrimazole, using an intravenous catheter and syringe. The patients received follow-up examinations on post-treatment days 7, 15, and 45. Results: The follow-up otomicroscopicexaminations revealed that 95% of the ear canals were entirely clean and that allsymptoms had resolved. The post-treatment scores of pain, aural fullness and itching weresignificantly lower than the pre-treatment scores (p<0.01). Conclusions: Filling the externalauditory meatus with 1% clotrimazole at a single visit is an easy, efficient, and cost-effectivetreatment for otomycosis. Additionally, high patient compliance makes this treatment superiorto long-term topical therapy.
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