뱀무 추출물의 항산화 활성 및 항균 효과
Effects of Antioxidant and Antimicrobial of Geum japonicum Thunb
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Abstract
Herbal medicine has been traditionally used for prevention and treatment of disease, because herbal medicine has few side effects in the human body. Anti-medicines such as antimicrobial medicine and anti-cancer medicine, which contains herbal medicine, are being studied vigorously by researchers. The effects of Geum Japonicum Thumb are restorative, blood circulation and detoxification. It also treats hematemesis, menstruation and furunculus. The ingredients of Geum Japonicum Thumb include geoside and tannin. This study measured antioxidative activation and antifungal activation by using Geum Japonicum Thumb water and methanol extract. The crude extract, which was used for this study, was Korean herbal medicine and the results are as follows. As Geum Japonicum Thumb extracts get stronger, the antioxidative activation tended to increase. The antioxidative activation hit its peak when the density of methanol extract was 120ug/ml. The experiment showed that a 1.0mm clear zone appeared when the density of the Geum Japonicum Thumb methanol extracts were 1000ug/ml in the Staphylococcus epidermidis and 1.1mm clear zone at Pseudomonas aeruginosa. The results of this study concludes that the antioxidative activation is lubricated in the Geum Japonicum Thumb extracts. In addition, the antifungal activation occurred in the fungus of the Staphylococcus epidermidis and the Pseudomonas aeruginosa.
참고문헌 (21)
- 배기환, "한국의 약용식물" (2003), 교학사
- Kim, S. J, "Cytotoxicity of methanol extracts of edible herbs against L1210 cells with the changes of antioxidant enzymes activities", 33(4), pp.376~383 (2002)
- Lee H. K, "Antioxidant, Antimutagenicity and anti- cancer activities of extracts from Cirsium japonicum var. ussuriense KITAMURA", 11(1), pp.53~61 (2003)
- Cui C. B, "Antioxidative, Antimutagenic and cytotoxic effects of Rhodiola sachalinensis extract", 3(2), pp.211~216 (2003)
- Jin L. H, "Antioxidant effects of the extracts of Acanthopanax senticosus", 33(4), pp.359~363 (2002)
- Lee, J. W, "Antioxidant activity of the water soluble browning reaction proucts isolated from korean Red Ginseng, 1. DPPH radical and hydrogen peroxide scavenging", 23(2), pp.176~181 (1999)
- Kim, C. H, "The activityof antioxidants and suppression of cancer cell proliferation in extracts of Orostachys japonicus. A,Berger", 11(1), pp.31~39 (2003)
- Williams B. W, "Use of free radical method to evauate antioxidant activity", 28, pp.25~30 (1995)
- Kim J. W, "Structures and antioxidant activity of diketopiperazines isolated from the mushroom Sarcodon aspratus", 48(1), pp.93~97 (2005)
- Oyaizu M, "Studies on products of bro- wning reaction;Antioxidative activities of products of browning reaction prepared from glucosamine", pp.307~315 (1986)
- Krenn CG, "Maintaining nitric oxide-induced airway relaxation with superoxide dismutase", 16(4), pp.419~424 (2007)
- Kim Y. S, "Antiherpetic activities of natural quer- citrin aloe and in combinations with nu- cleoside antiherpetic agents", 7, pp.168~173 (1999)
- Choi, E. Y, "Screening of Cytotoxicity and Antimicrobial effects of extracts from Atractylades macro- cephala Koidz", 16(2), pp.348~352 (2002)
- Nishiya. H, "aggregation inhibitors from Jyu-yaku(Hou- ttuyniaeHerb)" (1988)
- Cha, B. C, "Comparison of anti- oxidant and composition in Glycine max Merr and Glycine soja Siebold et Zucc", 72(1), pp.19~195 (1996)
- Chung, S. D, "Genetic diversity in korean popu- lations of Glycine soja(Fabaceae)", 38(1), pp.39~45 (1995)
- Xiong, Q, "Antioxidative effects of phe- nylethanoids from Cistanche deserticola", 19, pp.1580~1585 (1996)
- Kim, Y. I, "Isolation of anticancer agents from the leaves of Platycarya strobilacea S.", 27(3), pp.238~245 (1996)
- Keepers, "Comparison of the sulforhodamine B protein and tetrazolium assays for in vitro chemosensitivity testing", pp.897~900 (1991)
- Nam, S. H, "Screening of antioxidative activity of legume species", 46(1), pp.32~38
- Mun, Y. J, "The water ext- ract of caesalpinia sappan induces apop- tosis on human lung cancar call line, A549 cells", 16(3), pp.521~527 (2002)