본문 바로가기
KERD
논문KCI 등재

Low-noise fast-response readout circuit to improve coincidence time resolution

0

조회

0

다운로드

0

인용

0

참고문헌

키워드

주제분류원자력공학

초록

Time-of-flight (TOF) PET detectors with fast-rise-time scintillators and fast-single photon time resolution silicon photomultiplier (SiPM) have been developed to improve the coincidence timing resolution (CTR) to sub-100 ps. The CTR can be further improved with an optimal bandwidth and minimized electronic noise in the readout circuit and this helps reduce the distortion of the fast signals generated from the TOF-PET detector. The purpose of this study was to develop an ultra-high frequency and fully-differential (UF-FD) readout circuit that minimizes distortion in the fast signals produced using TOF-PET detectors, and suppresses the impact of the electronic noise generated from the detector and front-end readout circuits. The proposed UF-FD readout circuit is composed of two differential amplifiers (time) and a current feedback operational amplifier (energy). The ultra-high frequency differential (7 GHz) amplifiers can reduce the common ground noise in the fully-differential mode and minimize the distortion in the fast signal. The CTR and energy resolution were measured to evaluate the performance of the UF-FD readout circuit. These results were compared with those obtained from a high-frequency and single ended readout circuit. The experiment results indicated that the UF-FD readout circuit proposed in this study could substantially improve the best achievable CTR of TOF-PET detectors

Abstract

Time-of-flight (TOF) PET detectors with fast-rise-time scintillators and fast-single photon time resolution silicon photomultiplier (SiPM) have been developed to improve the coincidence timing resolution (CTR) to sub-100 ps. The CTR can be further improved with an optimal bandwidth and minimized electronic noise in the readout circuit and this helps reduce the distortion of the fast signals generated from the TOF-PET detector. The purpose of this study was to develop an ultra-high frequency and fully-differential (UF-FD) readout circuit that minimizes distortion in the fast signals produced using TOF-PET detectors, and suppresses the impact of the electronic noise generated from the detector and front-end readout circuits. The proposed UF-FD readout circuit is composed of two differential amplifiers (time) and a current feedback operational amplifier (energy). The ultra-high frequency differential (7 GHz) amplifiers can reduce the common ground noise in the fully-differential mode and minimize the distortion in the fast signal. The CTR and energy resolution were measured to evaluate the performance of the UF-FD readout circuit. These results were compared with those obtained from a high-frequency and single ended readout circuit. The experiment results indicated that the UF-FD readout circuit proposed in this study could substantially improve the best achievable CTR of TOF-PET detectors

참고문헌 (30)

  1. M. Conti, "Focus on time-of-flight PET : the benefits of improved time resolution", Eur. J. Nucl. Med. Mol. Imag, 38(6), pp.1147~1157 (2011)
  2. W. W. Moses, "Time of flight in PET revisited", IEEE Trans. Nucl. Sci, 50(5), pp.1325~1330 (2003)
  3. D. J. Kadrmas, "Impact of time-of-flight on PET tumor detection", J. Nucl. Med, 50(8), pp.1315~1323 (2009)
  4. S. Surti, "Investigation of time-of-flight benefit for fully 3-DPET", IEEE Trans. Med. Imag, 25(5), pp.529~538 (2006)
  5. P. Lecoq, "Pushing the limits in time-of-flight PET imaging", IEEE Trans. Radiat. Plasma Med. Sci, 1(6), pp.473~485 (2017)
  6. S. Vandenberghe, "Recent developments in time-of-flight PET", EJNMMI Phys, 3, pp.3~ (2016)
  7. K. Park, "Feasibility study of a time-of-flight brain position emission tomography employing individual channel readout electronics", Sensors, 21, pp.5566~ (2021)
  8. B. W. Jakoby, "Physical and clinical performance of the mCT time-of-flight PET", CT scanner, 2011, pp.56, 2375~2389
  9. M. Miller, "Characterization of the Vereos digital photon counting PET system", J. Nucl. Med, 56, pp.434~ (2015)
  10. A. M. Grant, "NEMA NU 2-2012 performance studies for the SiPM based TOF-PET component of the GE Signa PET", MR system, 2016, pp.43, 2334~2343
  11. D. F. C. Hsu, "Studies of next-generation silicon photomultiplier-based time-of-flight PET", CT system, 2017, pp.58, 1511~1518
  12. V. S. Joyce, "Performance characteristics of the digital biograph vision PET", CT system, 2019, pp.60(7), 1031~1036
  13. P. Lecoq, "Roadmap toward the 10 ps time-of-flight PET challenge", Phys. Med. Biol, 65, pp.21RM01~ (2020)
  14. S. Gundacker, "State of the art timing in TOF-PET detectors with LuAG, GAGG, and L(Y)SO scintillators of various sizes coupled to FBK-SiPMs", J. Instrum, 11, pp.P08008~ (2016)
  15. S. Gundacker, "Time of flight positron emission tomography towards 100ps resolution with L(Y)SO : an experimental and theoretical analysis", J. Instrum, 8, pp.P07014~ (2013)
  16. S. Gundacker, "Measurement of intrinsic rise times for various L(Y)SO and LuAG scintillators with a general study of prompt photons to achieve 10 ps in TOF-PET", Phys. Med. Biol, 61, pp.2802~2837 (2016)
  17. E. Venialgo, "Toward a full-flexible and fast-prototyping TOF-PET block detector based on TDC-on-FPGA", IEEE Trans. Radiat. Plasma Med. Sci, 3, pp.538~548 (2019)
  18. M. Krake, "Power-efficient high-frequency readout concepts of SiPMs for TOF-PET and HEP", Nucl. Instrum. Methods Phys. Res. A Accelators Spectrometer Detect. Assoc. Equip, 1039, pp.167032~ (2022)
  19. J. Jung, "An improved time over threshold method using bipolar signals", Phys. Med. Biol, 63, pp.135002~ (2018)
  20. J. Jung, "A diode-based symmetric charge division circuit with grounding path to reduce signal crosstalk and improve detector performance", IEEE Trans. Radiat. Plasma Sci, 6, pp.788~793 (2022)
  21. M. Nemallapudi, "Single photon time resolution of state of the art SiPMs", J. Instrum, 11, pp.P10016~ (2016)
  22. J. W. Cates, "Improved single photon time resolution for analog SiPMs with front end readout that reduces influence of electronic noise", Phys. Med. Biol, 63, pp.185022~ (2018)
  23. J. W. Cates, "Advances in coincidence time resolution for PET", Phys. Med. Biol, 61, pp.2255~2265 (2016)
  24. S. Gundacker, "Measurement of intrinsic rise times for various L(Y)SO and LuAG scintillators with a general study of prompt photons to achieve 10 ps in TOF-PET", Phys. Med. Biol, 61, pp.2802~2837 (2016)
  25. P. Lecoq, "Pushing the limits in time-of-flight PET imaging", IEEE Trans. Radiat. Plasma Sci, 1, pp.473~485 (2017)
  26. J. W. Cates, "Evaluation of a clinical TOF-PET detector design that achieves 100 ps coincidence time resolution", Phys. Med. Biol, 63, pp.115011~ (2018)
  27. S. Gundacker, "High-frequency SiPM readout advances measured coincidence time resolution limits in TOF-PET", Phys. Med. Biol, 64, pp.055012~ (2019)
  28. J. W. Cates, "Low power implementation of high frequency SiPM readout for Cherenkov and scintillation detectors in TOF-PET", Phys. Med. Biol, 67, pp.195009~ (2022)
  29. R. Ota, "Lead-free MCP to improve coincidence time resolution and reduce MCP direct interactions", Phys. Med. Biol, 66, pp.064006~ (2021)
  30. P. Lecoq, "New results for TOF-PET applications", IEEE Trans. Radiat. Plasma Sci, 6, pp.510~516 (2022)

관련 논문AI추천

Comparison of UV-enhanced SiPM technologies for estimating 511 keV photon arrival time using BGO Cherenkov LuminescenceGola Alberto, Gonzalez-Montoro Andrea, Levin Craig S., Merzi Stefano, Pourashraf Shirin한국원자력학회 · Nuclear Engineering and Technology2025 · 제57권 제4호Development of a proof-of-principle PET system using multi-time-over-threshold and FPGA without ADC or TDC김규범, 김규석, 김연경, 이수환, 정현우한국원자력학회 · Nuclear Engineering and Technology2025 · 제57권 제5호Optimized TOF-PET detector using scintillation crystal array for brain imaging최용, 김연경, 박건태, 임현태, 정지웅, 정진호한국원자력학회 · Nuclear Engineering and Technology2022 · 제54권 제7호Effects of reflector, surface treatment, and length of scintillation crystal on the performance of TOF-DOI PET detector with dual-ended readout최용, 윤조현, 이상원, 정지웅, 정진호한국원자력학회 · Nuclear Engineering and Technology2024 · 제56권 제7호Insights and simulation of metascintillator-based brain PET systems to enhance ToF capabilityBenlloch J.M., Bonifacio D.A.B., Gonzalez A.J., Konstantinou G., Latella R., Lecoq P., Murata H.M.한국원자력학회 · Nuclear Engineering and Technology2025 · 제57권 제5호어레이 타입 실리콘 광전증 배관의 신호 보상을 위해밀러 효과를 이용한 입력 회로 시뮬레이션권인용(사)한국방사선산업학회 · 방사선산업학회지2018 · 제12권 제1호

이 간행물의 다른 논문 (39건)