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Iodine-131 S Values for Use in Organ Dose Estimation of Korean Patients in Radioiodine Therapy

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초록

In the present study, iodine-131 S values (rT ) thyroid) were calculated for 30 target organs and tissuesusing the most recently developed Korean reference computational phantoms. The calculated S valueswere then compared with those of the International Commission on Radiological Protection (ICRP)reference computational phantoms to investigate the dosimetric impact of the Korean S values againstthose of the ICRP reference phantoms. The results showed significant differences in the S values due tothe different anatomical/morphological characteristics between the Korean and ICRP reference phantoms. Most target organs/tissues showed that the S values of the Korean reference phantoms are lowerthan those of the ICRP reference phantoms, by up to about 4 times (male spleen and female thymus). Exceptionally, three target organs/tissues (gonads, thyroid, and extrathoracic region) showed that the Svalues of the Korean reference phantoms are greater, by 1.5e3.7 times. We expect that the S valuescalculated in the present study will be beneficially used to estimate organ/tissue doses of Korean patientsunder radioiodine therapy

Abstract

In the present study, iodine-131 S values (rT ) thyroid) were calculated for 30 target organs and tissuesusing the most recently developed Korean reference computational phantoms. The calculated S valueswere then compared with those of the International Commission on Radiological Protection (ICRP)reference computational phantoms to investigate the dosimetric impact of the Korean S values againstthose of the ICRP reference phantoms. The results showed significant differences in the S values due tothe different anatomical/morphological characteristics between the Korean and ICRP reference phantoms. Most target organs/tissues showed that the S values of the Korean reference phantoms are lowerthan those of the ICRP reference phantoms, by up to about 4 times (male spleen and female thymus). Exceptionally, three target organs/tissues (gonads, thyroid, and extrathoracic region) showed that the Svalues of the Korean reference phantoms are greater, by 1.5e3.7 times. We expect that the S valuescalculated in the present study will be beneficially used to estimate organ/tissue doses of Korean patientsunder radioiodine therapy

참고문헌 (30)

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