일차성 슬관절 전치환술 환자에서 세균 비강 집락의 유병률
The Prevalence of Bacterial Nasal Colonization in Patients Undergoing Primary Total Knee Arthroplasty
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목적: 일차성 슬관절 전치환술 환자에서 술 전에 세균 비강 집락의 빈도를 조사하고 그 유무가 슬관절부 심부감염 발생빈도에 어떤 영향이 있는 지를 알아보고자 하였다. 대상 및 방법: 일차성 슬관절 전치환술 488명 784예를 대상으로 수술 전일에 비강면봉법으로 균동정을 시도하고, 1년 이상 추시가 가능했던 434명(88.9%) 중 술 전 세균 비강 집락이 있었던 환자들(제1군)과 그렇지 않은 경우 환자들(제2군)에서 추시 기간 중 심부감염 발생 여부를 조사하였다. 결과: 434명 중 69명(15.9%)에서 비강내에서 병원균이 동정되었다. 슬관절 전치환술 후 심부감염은 제1군 69명 113예 중에서는 1예(0.9%)에서, 제2군 365명 591예 중에서는 10예(1.7%)에서 발생하였고 양 군 간의 이러한 차이는 통계적으로 유의하지 않았다. 결론: 일차성 슬관절 전치환술 환자에서 술 전 세균 비강 집락의 빈도는 15.9%였고 비강 집락의 유무가 술 후 슬관절부 심부감염률에 미치는 영향은 없었다.
Abstract
Purpose: The objective of the current study was to investigate the prevalence of bacterial nasal colonization in patients who are undergoing primary total knee arthroplasty and to determine whether the prevalence affects the incidence of deep surgical site infections. Materials and Methods: Of the 488 consecutive patients (784 knees) who had been screened for bacterial nasal colonization using nasal swab cultures before elective total knee arthroplasties, 434 patients (88.9%) were available for review at one year postoperatively. We assessed the overall rate of deep surgical site infections in the patients with nasal carriage of bacteria (group I) and in those patients without any bacterial nasal colonization (group II), respectively. Results: Of the 434 patients, 69 (15.9%) had nasal carriage of bacteria. There was 1 infection (0.9%) among 113 knees of 69 patients in group I and 10 infections (1.7%) among 591 knees of 365 patients in group II. Those differences were not statistically significant. Conclusion: The prevalence of bacterial nasal colonization in patients undergoing primary total knee arthroplasty was 15.9% and the preoperative nasal carriage of bacteria did not affect the rate of deep surgical site infections.
참고문헌 (17)
- Greenwood D, "Medical microbiology. 17th ed", pp.174~175 (2007), Churchill Livingstone Elsevier
- Hanssen AD, "Prevention of deep periprosthetic joint infection", Instr Course Lect, 46, pp.555~567 (1997)
- Jacofsky DJ, "The infected total knee arthroplasty. In: Orthopaedic knowledge update. Hip and knee reconstruction. 3rd ed", American Academy of Orthopaedic Surgeons, 1771~2183 (2006)
- Kalmeijer MD, "Nasal carriage of Staphylococcus aureus is a major risk factor for surgical-site infections in orthopedic surgery", Infect Control Hosp Epidemiol, 21, pp.319~323 (2000)
- Kalmeijer MD, "Surgical site infections in orthopedic surgery: the effect of mupirocin nasal ointment in a double-blind, randomized, placebo- controlled study", Clin Infect Dis, 35, pp.353~358 (2002)
- Kim HC, "Preoperative risk factors for deep Infection following total knee replacements", J Korean Knee Soc, 21, pp.265~270 (2009)
- Kluytmans J, "Nasal carriage of Staphylococcus aureus: epidemiology, underlying mechanisms, and associated risks", Clin Microbiol Rev, 10, pp.505~520 (1997)
- Kuehnert MJ, "Prevalence of Staphylococcus aureus nasal colonization in the United States, 2001-2002", J Infect Dis, 193, pp.172~179 (2006)
- Park BG, "Nasal carriage of methicillin- resistant staphylococcus aureus among healthcare workers and community students in 1997 and 2006", Korean J Nosocomial Infect Control, 12, pp.85~90 (2007)
- Parvizi J, "Resistant organisms in infected total knee arthroplasty: occurrence, prevention, and treatment regimens", Instr Course Lect, 58, pp.271~278 (2009)
- Parvizi J, "Decolonization of drug-resistant organisms before total joint arthroplasty", Instr Course Lect, 59, pp.131~137 (2010)
- Price CS, "Staphylococcus aureus nasal colonization in preoperative orthopaedic outpatients", Clin Orthop Relat Res, 466, pp.2842~2847 (2008)
- Rao N, "preoperative decolonization protocol for staphylococcus aureus prevents orthopaedic infections", Clin Orthop Relat Res, 466, pp.1343~1348 (2008)
- Sankar B, "The role of MRSA screening in joint-replacement surgery", Int Orthop, 29, pp.160~163 (2005)
- Sivaraman K, "Staphylococcus aureus nasal carriage and its contributing factors", Future Microbiol, 4, pp.999~1008 (2009)
- Wilcox MH, "Use of perioperative mupirocin to prevent methicillin-resistant Staphylococcus aureus (MRSA) orthopaedic surgical site infections", J Hosp Infect, 54, pp.196~201 (2003)
- Zimmerli W, "Prosthetic-joint infections", N Engl J Med, 351, pp.1645~1654 (2004)
