Factors affecting range of motion following two-stage revision arthroplasty for chronic periprosthetic knee infection

Abstract

The purpose of this study was to evaluate factors that affect range of motion (ROM) following two-stage revision arthroplasty as a treatment for chronic periprosthetic knee infection.A total of 98 patients diagnosed with chronic periprosthetic joint infection (PJI) following primary total knee arthroplasty between January 2009 and December 2019 and then underwent two-stage revision arthroplasty were reviewed retrospectively. Multiple regression analysis was performed to evaluate the factors that affect ROM after two-stage revision arthroplasty. ROM after two-stage revision arthroplasty was used as a dependent variable, while age at the time of surgery, ROM at PJI diagnosis, ROM after the first-stage surgery, the interval between the first-stage surgery and the second-stage surgery, whether a re-operation was performed before the second-stage surgery, culture results (culture negative or culture positive), and body mass index (BMI) were used as independent variables. Multiple regression analysis ( R 2 = 0.843) revealed that among the independent variables, ROM ( β = 0.604, P < 0.001) after the first-stage surgery, whether a re-operation was performed before the second-stage surgery ( β =  − 8.847, P < 0.001), the interval between the first-stage surgery and the second-stage surgery ( β = − 0.778, P = 0.003), and BMI ( β =  − 0.698, P = 0.041) were associated with ROM after two-stage revision arthroplasty, the dependent variable. In two-stage revision arthroplasty for chronic periprosthetic knee infection, ROM after the first-stage surgery, whether a re-operation was performed before the second-stage surgery, the interval between the first-stage surgery and the second-stage surgery, and BMI were found to be factors that were associated with ROM after two-stage revision arthroplasty.