대사증후군 환자에서 영양소 섭취 상태와 우울증과의 연관성: 2014년 국민건강영양조사 자료를 이용하여
Relationship between Dietary Intake and Depression in Metabolic Syndroem among Korean Adults: Korea National Health and Nutrition Examination Survey 2014
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우울증과 대사증후군은 상호 연관성이 있으며, 영양소 섭취 상태가 두 질환의 발생과 예방에 영향을 미침에도 불구하고 대사증후군 환자를 대상으로 한 우울증 환자의 영양소 섭취 상태에 대한 연구가 국내는 물론 국외에서도 적은 편이다. 이에 본 연구는 국민건강영양조사에 참여한 대사증후군 환자를 대상으로 우울증과 영양소 섭취 상태의 연관성을 알아보고자 하였다. 본 연구는 국민건강영양조사 자료 중 제 6기 2차 (2014년) 자료를 분석하였으며, 만 20세에서 60세 사이의 대사증후군 환자 1.471명 중 의사에 의한 우울증 진단여부가 확인이 되는 1,334명을 최종 대상자로 하여 이들의 영양소 섭취 상태와 우울증과의 연관성을 분석하였다. 대사증후군 환자를 남녀로 구분하여 우울증 군과 정상 군의 영양소 섭취 상태를 비교하였을 때, 니아신 섭취량이 남성에서 각각 14.5±6.7mg과 17.8±9.7 mg으로 우울증 군이 유의하게 (P=0.047) 낮았고, 여성에서도 각각 11.4±5.4 mg과 13.1±8.0 mg으로 우울증 군이 유의하게(P=0.025) 낮았다. 결론적으로 본 연구에서는 대사증후군이 있는 성인에서 우울증이 니아신 섭취량과 관련이 있음을 확인할 수 있었다. 이는 대사증후군 환자에서 우울증에 대한 영양소 섭취 상태 평가가 의미가 있음을 시사하며, 또한 영양학적 중재가 대사증후군 환자의 우울증 유병을 감소시킬 수 있을 것으로 생각된다.
Abstract
Objectives: Metabolic syndrome and depression are interconnected disorders. Although many studies have assessed the association between dietary intake and each disorder independently, few studies have examined the association between depression and dietary intake in patients with metabolic syndrome. Our study examined the association between depression and dietary intake in adults with metabolic syndrome. Methods: We analyzed the second data set (2014) from the sixth KNHNES. Of the patients with metabolic syndrome, the final study population comprised 1,334 patients, aged 20 to 60 years, with metabolic syndrome as defined by KNHNES and depression diagnosed by a physician. We examined the patients’ dietary intake obtained using the 24-h recollection method in KNHNES. Results: Depression group had a lower niacin dietary intake than those without depression in both male and female (male P=0.047, female P=0.025). None of the other components had any association between depression group and those without depression group in both male and female. Conclusions: This study demonstrates that a low dietary intake of niacin may be related to the depression in patients with metabolic syndrome. The results indicate that it is worthwhile to evaluate the nutritional status in patients who have been diagnosed with both metabolic syndrome and depression.
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