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Melatonin Induced Changes in Specific Growth Rate, Gonadal Maturity, Lipid and Protein Production in Nile Tilapia Oreochromis niloticus (Linnaeus 1758)

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We have investigated the effect of melatonin (MLT) on specific growth rate (SGR% day-1), condition factor (k), gonado-somatic-index (GSI), histological structures of gonads, serum as well as gonadal protein and lipid in Nile tilapia Oreochromis niloticus. MLT treatment in the dose of 25 g/L for three weeks reduced SGR% day-1 (0.90.04) as compared to control (1.230.026). The GSI value was significantly (p<0.05) reduced to 1.770.253 from control where it was 2.560.25. Serum protein level increased from 9.332.90 mg/ml (control) to 11.671.45 mg/ml after MLT treatment while there was depressed serum triglycerides (86.161.078 mg/dl) and cholesterol (126.660.88 mg/dl) as compared to control values where these were 123.01.23 mg/dl and 132.01.65 mg/dl respectively. Histological structure of ovary showed small eggs of early perinucleolus stage after MLT treatment while testicular structure of control and MLT treated fish was more or less similar. It is concluded that exogenous melatonin suppressed SGR% day-1, GSI, ovarian cellular activity, protein and lipid biosynthesis, in tilapia suggesting that melatonin is useful in manipulating the gonadal maturity in fishes.

Abstract

We have investigated the effect of melatonin (MLT) on specific growth rate (SGR% day-1), condition factor (k), gonado-somatic-index (GSI), histological structures of gonads, serum as well as gonadal protein and lipid in Nile tilapia Oreochromis niloticus. MLT treatment in the dose of 25 g/L for three weeks reduced SGR% day-1 (0.90.04) as compared to control (1.230.026). The GSI value was significantly (p<0.05) reduced to 1.770.253 from control where it was 2.560.25. Serum protein level increased from 9.332.90 mg/ml (control) to 11.671.45 mg/ml after MLT treatment while there was depressed serum triglycerides (86.161.078 mg/dl) and cholesterol (126.660.88 mg/dl) as compared to control values where these were 123.01.23 mg/dl and 132.01.65 mg/dl respectively. Histological structure of ovary showed small eggs of early perinucleolus stage after MLT treatment while testicular structure of control and MLT treated fish was more or less similar. It is concluded that exogenous melatonin suppressed SGR% day-1, GSI, ovarian cellular activity, protein and lipid biosynthesis, in tilapia suggesting that melatonin is useful in manipulating the gonadal maturity in fishes.

참고문헌 (51)

  1. Aarseth, J. J., "Melatonin implantation during spring and summer does not affect the seasonal rhythm of feeding in anadromous Arctic charr (Salvelinus alpines)", Polar Biol, 33, pp.379~388 (2010)
  2. Altun, A., "Melatonin: therapeutic and clinical utilization", Int. J. Clin. Pract, 61, pp.835~845 (2007)
  3. Alvaro, J. M. R., "Effects of melatonin implants on reproduction and growth of turbot brood stock", Aquacult. Int, 9, pp.477~487 (2001)
  4. Bayarri, M. J., "Effects of photoperiod manipulation on the daily rhythms of melatonin and reproductive hormones in caged European sea bass Dicentrachus labrax", Gen. Comp. Endocrinol, 136, pp.72~81 (2004)
  5. Bligh, E. G., "A rapid method of total lipid extraction and purification", Can. J. Biochem. Physiol, 37, pp.911~917 (1959)
  6. Borg, B., "Gonadal effects of Melatonin in the three-spined stickeleback, Gasterosteus aculeatus L., during different season and photoperiods", Reprod. Nutr, 21, pp.919~927 (1981)
  7. Bornestaf, C., "Melatonin and maturation pace in female three-spined stickleback, Gasterosteus aculeatus", Gen. Comp. Endocrinol, 122, pp.341~348 (2001)
  8. Boutin, J. A., "Molecular tools to study melatonin pathways and actions", Trends Pharmacol. Sci, 26, pp.412~419 (2005)
  9. Bromage, N., "The environmental regulation of maturation in farmed finfish with special reference to the role of photoperiod and melatonin", Aquaculture, 197, pp.63~98 (2001)
  10. Bromage, N. R., "How do photoperiod, the pineal, melatonin and circannual rhythms interact to coordinate seasonal reproduction in salmonid fish?", Reprod. Physiol, 95, pp.164~166 (1995)
  11. Caniato, R., "Melatonin in plants", Adv. Exp. Med. Biol, 527, pp.593~597 (2003)
  12. Chattoraj, A., "Melatonin accelerates maturation inducing hormone (MIH) induced oocyte maturation in carps", Gen. Comp. Endocrinol, 140, pp.145~155 (2005)
  13. Chattoraj, A., "Localization and dynamics of melatonin receptor in the ovary of carp, Catla catla in relation to serum melatonin levels", Com. Biochem. Physiol. A, Mol. Integr. Physiol, 152, pp.327~333 (2009)
  14. Chattoraj, A., "Temporal relationship between the circulating profiles of melatonin and ovarian steroids under natural photothermal conditions in an annual reproductive cycle in carp Catla catla", Biol. Rhythm. Res, 40, pp.347~359 (2009)
  15. Delahunty, G., "Hypoglycemic effects of melatonin in the goldfish, Carassius auratus", Comp. Biochem. Physiol, 78, pp.871~875 (1984)
  16. Delgado, M. J., "Effects of daily melatonin injection on the photoperiodic gonadal response of the female frog Rana ridibunda", Comp. Biochem. Physiol, 76, pp.289~292 (1983)
  17. De Pedro, N., "Melatonin reduces body weight in goldfish (Carassius auratus): effects on metabolic resources and some feeding regulators", J. Pineal Res, 45, pp.32~39 (2008)
  18. Falcón, J., "Melatonin effects on the hypothalamo-pituitary axis in fish", Trends Endocrinol. Metabol, 18(2), pp.81~88 (2007)
  19. Falcon, J., "Structural and functional evaluation in pineal melatonin system in vertebrates", Ann. NY Acad. Sci, 1163, pp.101~111 (2009)
  20. Falcon, J, "Current knowledge on the melatonin system in teleost fish", Gen. Comp. Endocrinol, 165, pp.469~482 (2009)
  21. Fatemeh, M., "Effects of melatonin on histopathological changes after experimental ovarian torsion- detorsion in cat", Iran. J. Reprod. Med, 5, pp.177~181 (2007)
  22. Ghosh, J., "Seasonal effects of melatonin on ovary and plasma gonadotropin and vitellogenin levels in intact and pinealectomized catfish, Clarias batrachus (Linn)", Ind. J. Exp. Biol, 43, pp.224~232 (2005)
  23. Guerrero, H. Y., "Daily and annual variations of plasma melatonin in the annual gonadal maturation", Proceedings of the 8th international symposium on reproductive physiology of fish, 32, pp.22~24 (2007)
  24. Joy, K. P., "Seasonal effect of administration of melatonin and 5- methoxy-trytophol on ovarian activity in the catfish Heteropneustes fossilis (Bloch)", J. Pineal Res, 10, pp.65~70 (1991)
  25. Koger, C. S., "Variations of light and temperature regimes and resulting effects on reproductive parameters in medaka (Oryzias latipes)", Biol. Reprod, 61, pp.1287~1293 (1999)
  26. Lemer, A. B., "Isolation of melatonin, the pineal gland factor that lightens melanocytes", J. Am. Chem. Soc, 80, pp.2587~ (1958)
  27. Lopez, L. F., "Melatonin effects on food intake and activity rhythms in two fish species with different activity patterns: Diurnal (goldfish) and nocturnal (tench)", Comp. Biochem. Physiol, 144, pp.180~187 (2006)
  28. Lowry, O. H., "Protein measurement with folin’s phenol reagents", J. Biol. Chem, 193, pp.265~275 (1951)
  29. Maitra, S. K., "Implication of melatonin in oocyte maturation in Indian major carp Catla catla", Fish Physiol. Biochem, 31, pp.201~207 (2005)
  30. Maitra, S. K., "Seasonal reproduction in fish: a functional interplay between the pineal organ and photoperiods", J. Endocrinol. Reprod, 5, pp.1~12 (2001)
  31. Mamdouh, M. A, "Oxidative stress in streptozotocin - induced diabetic rats: Effects of garlic oil and melatonin", Comp. Biochem. Physiol. Part A, 135, pp.539~547 (2003)
  32. Oppedal, F., "Artificial light and season affect vertical distribution and swimming behaviors of post-smolt Atlantic salmon in sea cages", J. Fish Biol, 58, pp.1570~1584 (2001)
  33. Oppedal, F., "Growth performance and sexual maturation in diploid and triploid Atlantic salmon (Salmo salar L.) in seawater tanks exposed to continuous light or simulated natural photoperiod", Aquaculture, 215, pp.145~162 (2003)
  34. Paredes, S. D., "Phytomelatonin: a review", J. Exp. Bot, 60, pp.57~69 (2009)
  35. Pinillos, M. L., "Food intake inhibition by melatonin in goldfish (Carassius auratus)", Physiol. Behav, 72, pp.629~634 (2001)
  36. Popek, W., "Effect of melatonin on dopamine secretion in the hypothalamus of mature female common carp, Cyprinus carpio L", Acta Ichthyol. Piscat, 36, pp.134~141 (2006)
  37. Porter, M. J. R., "The use of cage lighting to reduce plasma melatonin in Atlantic salmon (Salmo salar) and its effects on the inhibition of grilling", Aquaculture, 176, pp.237~244 (1999)
  38. Reiter, R. J., "Melatonin: mechanisms and actions as an antioxidant", Curr. Top. Biophys, 24, pp.171~183 (2000)
  39. Renuka, K., "Melatonin-induced changes in ovarian function in the freshwater fish Channa punctatus (Bloch) held in long days and continuous light", Gen. Comp. Endocrinol, 165, pp.42~46 (2010)
  40. Shi Qiong, "Melatonin is involved in sex change of the rice field eel, Monopterus albus Zuiew", Rev. Fish Biol. Fish, 15, pp.23~36 (2005)
  41. Shulman, G. E., "Life cycles of fish physiology and biochemistry" (1974), Hulsted Press, John Wiley and sons
  42. Singh, A. K., "Role of pineal melatonin during environmental sex determination in fishes. In: Recent advances in Hormonal Physiology of fish and Shell fish Reproduction", pp.265~271 (2009), Narendra Publishing House
  43. Sokołowska, E., "Seasonal changes in brain melatonin concentration in the three-spined stickleback (Gasterosteus aculeatus): towards an endocrine calendar", Comp. Biochem. Physiol. Part A: Mol. Integr. Physiol, 13, pp.365~369 (2004)
  44. Sreenivasan, V., "Melatonin and human reproduction: shedding light on the darkness hormone", Gynecol. Endocrinol, 25, pp.779~785 (2009)
  45. Stein, E. A., "Text book of clinical chemistry", pp.1818~1829 (1986), W. B Saunders Co
  46. Sundararaj, B. I., "Effects of melatonin and prolactin treatment on the hypophysial- ovarian system in the catfish, Heteropneustes fossilis (Bloch)", Gen. Comp. Endocrinol, 129, pp.84~96 (1976)
  47. Tamura, H., "Melatonin and the ovary: physiological and pathophysiological implications", Fertil. Steril, 92, pp.328~343 (2009)
  48. Uraski, H., "Effect of restricted photoperiods and melatonin: administration on gonadal weights in Japanese Kilifish", J. Endocrinol, 55, pp.619~620 (1972)
  49. Vanecek, J., "Cellular mechanism of melatonin action", Physiol. Rev, 78, pp.687~711 (1998)
  50. Wang, Y., "Ultrastructure and melatonin 1a receptor distribution in the ovaries of African ostrich chick", Cytotechnology, 56, pp.187~195 (2008)
  51. Zhdanova, I. V., "Melatonin promotes sleep-like state in zebra fish", Brain Res, 903, pp.263~268 (2001)

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