Study on the Changes in Enzyme and Insulin-like Growth Factor-1 Concentrations in Blood Serum and Growth Characteristics of Velvet Antler during the Antler Growth Period in Sika Deer (Cervus nippon)
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This study was conducted to investigate changes in blood enzyme parameters and to evaluate the relationship between insulin-like growth factor-1 (IGF-1), antler growth and body weight during the antler growth of sika deer (Cervus nippon). Serum enzyme activity and IGF-1 concentrations were measured in blood samples collected from the jugular and femoral veins at regular intervals during the antler growth period. Blood samples were taken in the morning from fasted stags (n = 12) which were healthy and showed no clinical signs of disease. Alfalfa was available ad libitum and concentrates were given at 1% of body weight to all stags. The experimental diet was provided at 9 am with water available at all times. There were no significant differences in alkaline phosphatase, aspartate aminotransferase, and alanine aminotransferase during antler growth, but alkaline phosphatase concentrations increased with antler growth progression, and the highest alkaline phosphatase concentration was obtained 55 days after antler casting. Serum IGF-1 concentrations measured from blood samples taken from the jugular vein during antler growth, determined that levels of IGF-1 was associated with body weight and antler growth patterns. Serum IGF-1 concentrations were higher at the antler cutting date than other sampling dates. Antler length increased significantly during antler growth (p<0.001), and there was a similar trend to between right and left beams. Body weight increased with antler growth but was not significant. Consequently it appeared that serum alkaline phosphatase concentration was related to antler growth and both antler growth and body weight were associated positively with IGF-1 concentrations during antler growth.
Abstract
This study was conducted to investigate changes in blood enzyme parameters and to evaluate the relationship between insulin-like growth factor-1 (IGF-1), antler growth and body weight during the antler growth of sika deer (Cervus nippon). Serum enzyme activity and IGF-1 concentrations were measured in blood samples collected from the jugular and femoral veins at regular intervals during the antler growth period. Blood samples were taken in the morning from fasted stags (n = 12) which were healthy and showed no clinical signs of disease. Alfalfa was available ad libitum and concentrates were given at 1% of body weight to all stags. The experimental diet was provided at 9 am with water available at all times. There were no significant differences in alkaline phosphatase, aspartate aminotransferase, and alanine aminotransferase during antler growth, but alkaline phosphatase concentrations increased with antler growth progression, and the highest alkaline phosphatase concentration was obtained 55 days after antler casting. Serum IGF-1 concentrations measured from blood samples taken from the jugular vein during antler growth, determined that levels of IGF-1 was associated with body weight and antler growth patterns. Serum IGF-1 concentrations were higher at the antler cutting date than other sampling dates. Antler length increased significantly during antler growth (p<0.001), and there was a similar trend to between right and left beams. Body weight increased with antler growth but was not significant. Consequently it appeared that serum alkaline phosphatase concentration was related to antler growth and both antler growth and body weight were associated positively with IGF-1 concentrations during antler growth.
참고문헌 (30)
- AOAC., "Official Methods of Analysis" (1990), Association of official analytical chemists
- Bubenik, G. A., "The effect of artificial photoperiodicity and antiandrogen treatment on the antler growth and plasma levels of LH, FSH, testosterone, prolactin and alkaline phosphatase in the male white-tailed deer", Comp. Biochem. Physiol. Physiol, 87, pp.551~559 (1987)
- Catley, A., "Haematology of clinically normal and sick captive reindeer (Rangifer tarandus)", Vet. Rec, 126, pp.239~241 (1990)
- Chao, C. C., "Metabolism of calcium and phosphorus during pregnancy and lactation in white-tailed deer", Acta Endocrinol, 109, pp.269~275 (1985)
- Chapple, R. S., "Haematology and serum biochemistry of captive unsedated chital deer (Axis axis) in Australia", J. Wildl Disease, 27, pp.396~406 (1991)
- Choi, S. H., "Biological contents of velvet antler and femoral venous blood in farmed Elk (cervus Canadensis)", Korean J. Vet. Clin. Med, 15, pp.251~254 (1998)
- Eiben, B., "Seasonal variations of serum 1,25-dihydroxyvitamin D3 and alkaline phosphatase in relation to the antler formation in the fallow deer (Dama dama L.)", Acta Endocrinol, 107, pp.141~144 (1984)
- Gluckman, P. D., "Parturition-related changes in insulin-like growth factors-I and -II in the perinatal lamb", J. Endocrinol, 99, pp.223~232 (1983)
- Goss, "Deer Antlers: Regeneration, Function and Evolution", pp.133~171 (1983), Academics press
- Haigh, J. C., "Farming Wapiti and Red Deer", pp.149~153 (1993), Mosby-Year Book. Inc
- Hofmann, R. R., "Digestive physiology the deer. Their morphophysiological specialization and adaptation", The Royal Society of NZ Bulletin, 22, pp.393~407 (1985)
- Hofmann, R. R., "Evolutionary steps of ecophysiological adaptation and diversification of ruminants : a comparative view of their digestive system", Oecologia, 78, pp.443~457 (1989)
- Karen, L.V., "Circulating levels of 1,25-dihydrozyvitamin D, alkaline phosphatase, hydroxyproline, and osteocalcin associated with antler growth in white-tailed deer", Acta Endocrinol, 118, pp.407~414 (1988)
- Karesh, W. B., "Neonatal hematology of selected species of cervidae and bovidae", J. Zoo Anim. Med, 17, pp.138~146 (1986)
- Kay, R. N. B., "Digestive Physiology and Metabolism in Ruminants", pp.793~761 (1980)
- Maeda, Y., "Haematology in sika deer", Jpn. J. Vet. Sci, 52, pp.35~41 (1990)
- Marco, I., "Effect of the method of capture on the haematology and blood chemistry of red deer (Cervus elaphus)", Res. Vet. Sci, 66, pp.81~84 (1999)
- Muir, P. D., "Effect of winter nutrition on antler development in red deer (Cervus elaphus): A field study", NZ J. Agric. Res, 31, pp.145~150 (1988)
- Muir, P. D., "Changes in blood content and histology during growth of antlers in red deer (Cervus elaphus) and their relationship to plasma testosterone levels", J. Anat, 158, pp.31~42 (1988)
- Price, J., "Exploring the mechanisms regulating regeneration of deer antlers", Phil. Trans. R. Soc. Lond. B, 359, pp.809~822 (2004)
- Reid, T. C., "Biology of Deer Production", pp.72~76 (1985), Royal Soc. NZ Bull
- Sakkinen, H., "Nutritional-induced changes in blood chemical parameters of pregnant reindeer hinds (Rangifer tarandus tarandus)", Small Rumin. Res, 32, pp.211~221 (1999)
- SAS Institute Inc., "SAS User's Guide, ver 6.03" (1988), Cary
- Spraker, T. R., "Zoo and Wild Animal Medicine: Current Therapy", pp.481~488 (1993), W.B. Saunders Co.
- Stephen, S. D., "Concentrations of insulin-like growth factor-I in adult male white-tailed deer (Odocoileus virginianus): associations with serum testosterone, morphometrics and age during and after the breeding season", Comp. Biochem. Physiol. Part A: Mol. Integr. Physiol, 129, pp.887~895 (2001)
- Suttie, J. M., "Antler Development in Cervidae", pp.61~71 (1982), Texas A & M Univ. Press
- Suttie, J. M., "Insulin-like growth factor 1 : antler stimualating hormone?", Endocrinology, 116, pp.846~848 (1985)
- Suttie, J. M., "Photoperiod associated changers in insulin like growth factor-1 in reindeer", Endocrinology, 129, pp.679~682 (1991)
- Suttie, J. M., "Effects of Melatonin implants on insulinlike growth factor 1 in male red deer (Cervus elaphus)", Gen. Comp. Endocrinol, 87, pp.111~119 (1992)
- Van Soest, P. J., "Methods of dietary fiber, neutral detergent fiber, and nonstarch polysaccharides in relation to animal nutrition", J. Dairy Sci, 74, pp.3583~3597 (1991)