Effects of Organic Light-Emitting Diodes on Circadian Rhythm and Sleep
1
조회
0
다운로드
0
인용
0
참고문헌
키워드
초록
Objective Organic light-emitting diodes (OLEDs) emit less blue light than traditional light-emitting diodes (LEDs), and we previously found that early-night OLED light exposure (LE) delays the melatonin phase by less than LED at a color temperature of 4,000 K. As a follow-up study, we investigated the effects of OLED and LED at a different color temperature (3,000 K) on melatonin profile, sleep, and vigilance.Methods 24 healthy subjects (27.5±5.1 years) were exposed to three light conditions [OLED, LED, and dim light (DL)] from 17:30 to 24:00, in a random order and with a 1-week interval. Saliva samples for melatonin were taken every hour from 18:00 to 24:00. Polysomnography (PSG) and a psychomotor vigilance test (PVT) were performed.Results Melatonin onset time was significantly delayed under OLED and LED compared with DL, with no significant difference between OLED and LED. The mean melatonin level at 24:00 under LED was lower than that under DL, but there was no significant difference between OLED LE and DL. The percentage of slow wave sleep (N3) in LED was significantly lower than in OLED.Conclusion Exposure to light in the evening can suppress melatonin secretion late at night and disturb deep sleep, and those effects are slightly worse under LED than OLED.
Abstract
Objective Organic light-emitting diodes (OLEDs) emit less blue light than traditional light-emitting diodes (LEDs), and we previously found that early-night OLED light exposure (LE) delays the melatonin phase by less than LED at a color temperature of 4,000 K. As a follow-up study, we investigated the effects of OLED and LED at a different color temperature (3,000 K) on melatonin profile, sleep, and vigilance.Methods 24 healthy subjects (27.5±5.1 years) were exposed to three light conditions [OLED, LED, and dim light (DL)] from 17:30 to 24:00, in a random order and with a 1-week interval. Saliva samples for melatonin were taken every hour from 18:00 to 24:00. Polysomnography (PSG) and a psychomotor vigilance test (PVT) were performed.Results Melatonin onset time was significantly delayed under OLED and LED compared with DL, with no significant difference between OLED and LED. The mean melatonin level at 24:00 under LED was lower than that under DL, but there was no significant difference between OLED LE and DL. The percentage of slow wave sleep (N3) in LED was significantly lower than in OLED.Conclusion Exposure to light in the evening can suppress melatonin secretion late at night and disturb deep sleep, and those effects are slightly worse under LED than OLED.
참고문헌 (24)
- Gooley JJ, "Exposure to room light before bedtime suppresses melatonin onset and shortens melatonin duration in humans", J Clin Endocrinol Metab, 96, pp.E463~ (2011)
- Bonmati-Carrion MA, "Protecting the melatonin rhythm through circadian healthy light exposure", Int J Mol Sci, 15, pp.23448~23500 (2014)
- Brainard GC, "Action spectrum for melatonin regulation in humans : evidence for a novel circadian photoreceptor", J Neurosci, 21, pp.6405~6412 (2001)
- Thapan K, "An action spectrum for melatonin suppression : evidence for a novel non-rod, non-cone photoreceptor system in humans", J Physiol, 535, pp.261~267 (2001)
- Wahl S, "The inner clockBlue light sets the human rhythm", J Biophotonics, 12, pp.e201900102~ (2019)
- Hatori M, "Global rise of potential health hazards caused by blue light-induced circadian disruption in modern aging societies", NPJ Aging Mech Dis, 3, pp.9~ (2017)
- Jou JH, "Enabling a blue-hazard free general lighting based on candle light-style OLED", Opt Express, 23, pp.A576~ (2015)
- Jou JH, "Blue-hazard-free Candlelight OLED", J Vis Exp, (121), pp.54644~ (2017)
- 박혜리, "Effects of Evening Exposure to Light from Organic Light-Emitting Diodes on Melatonin and Sleep", Journal of Clinical Neurology, 16(3), pp.401~407 (2020), 대한신경과학회
- Buysse DJ, "The Pittsburgh Sleep Quality Index : a new instrument for psychiatric practice and research", Psychiatry Res, 28, pp.193~213 (1989)
- Beck AT, "Comparison of Beck Depression Inventories-IA and-II in psychiatric outpatients", J Pers Assess, 67, pp.588~597 (1996)
- Bastien CH, "Validation of the Insomnia Severity Index as an outcome measure for insomnia research", Sleep Med, 2, pp.297~307 (2001)
- Horne JA, "A self-assessment questionnaire to determine morningness-eveningness in human circadian rhythms", Int J Chronobiol, 4, pp.97~110 (1976)
- Benloucif S, "Measuring melatonin in humans", J Clin Sleep Med, 4, pp.66~69 (2008)
- Berry RB, "AASM Scoring Manual Updates for 2017(Version 2. 4)", J Clin Sleep Med, 13, pp.665~666 (2017)
- Basner M, "Validity and sensitivity of a brief Psychomotor Vigilance Test(PVT-B)to total and partial sleep deprivation", Acta Astronaut, 69, pp.949~959 (2011)
- MacLean AW, "Psychometric evaluation of the Stanford Sleepiness Scale", J Sleep Res, 1, pp.35~39 (1992)
- Arendt J, "Melatonin, circadian rhythms, and sleep", N Engl J Med, 343, pp.1114~1116 (2000)
- Pauley SM, "Lighting for the human circadian clock : recent research indicates that lighting has become a public health issue", Med Hypotheses, 63, pp.588~596 (2004)
- Lee SI, "Melatonin suppression and sleepiness in children exposed to blue-enriched white LED lighting at night", Physiol Rep, 6, pp.e13942~ (2018)
- Tyan YS, "Organic light-emitting-diode lighting overview", J Photonics Energy, 1, pp.011009~ (2011)
- Yang X, "Functionalization of phosphorescent emitters and their host materials by main-group elements for phosphorescent organic light-emitting devices", Chem Soc Rev, 44, pp.8484~8575 (2015)
- NS Cho, "Current status of OLED techonology and market", Polymer Sci Technol, 24, pp.126~134 (2013)
- Shrivastava D, "How to interpret the results of a sleep study", J Community Hosp Intern Med Perspect, 4, pp.24983~ (2014)