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소변 농축 기전과 요소운반체

Urine Concentrating Mechanism and Urea Transporters

김동언
대한소아신장학회 (The Korean Society Of Pediatric Nephrology)|2005.04|Childhood Kidney Diseases (Childhood Kidney diseases)|제9권 제1호|pp. 1-7

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참고문헌

주제분류소아과학

초록

Abstract

The production of concentrated urine is achieved by countercurrent multiplication in the renal medulla. The single effect of the outer medulla is the active NaCl reabsorption in the thick ascending limb, while the single effect of the inner medulla is the passive efflux of NaCl through the thin ascending limb. The passive mechanism in the inner medulla requires a high interstitial urea concentration which is maintained by intrarenal recycling of urea. During the past decade, many transport proteins involved in the urine concentrating mechanism have been cloned, which has enabled us to understand the countercurrent multiplication mechanism on a molecular basis. This review will summarize the locations and functions of the renal medullary transport proteins, and the recent insights that have been acquired into the long term regulation of urea transporters.

참고문헌 (29)

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관련 논문AI추천

소변농축과 장력 스트레스에 대한 콩팥 수질 세포들의 적응김동언대한소아신장학회 · Childhood Kidney Diseases2007 · 제11권 제2호흰쥐 콩팥에서 요소운반체-A의 발현: 미세구조적 면역세포화학법김진, 김완영, 임선우, 정주영, 정진웅, 차정호, 한기환한국현미경학회 · Applied Microscopy2002 · 제32권 제2호신장에서 V2-수용체를 통한 옥시토신의 aquaporin-2 발현 조절김진, 김근호, 나기영, 오윤규, 이정상, 전은실, 주권욱, 한진석대한내과학회 · 대한내과학회지2002 · 제62권 제3호Renal Sodium Transporters and Water Channels김혜영대한고혈압학회 · Clinical Hypertension2013 · 제19권 제1호배뇨반사에서 퓨린수용체의 생리적, 병태생리적 기능김대경대한배뇨장애요실금학회 · International Neurourology Journal2008 · 제12권 제2호요검사를 통한 신장질환의 임상적 접근이강욱대한가정의학회 · Korean Journal of Family Medicine2003 · 제24권 제2호

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