Mini-review: 멜라민에 의한 신요로계 결석
Mini-review; Melamine-related Urinary Stone Disease
2
조회
0
다운로드
2
인용
0
참고문헌
키워드
초록
2008년 말 발생한 멜라민 파동은 멜라민에 오염된 분유를 섭취한 영아들에서 요로계 결석이 발생한 것으로부터 비롯되었다. 멜라민 관련 요로계 결석의 위험인자는 3세 미만의 나이, 많은 멜라민 섭취량과 탈수, 요산의 요 배설량 증가 등의 일반적인 요로계 결석 위험인자의 동반이다. 멜라민 관련 결석은 주 성분이 요산이므로 수분 공급과 소변 알칼리화의 보존적인 치료로 회복되는 경우가 대부분이다.
Abstract
Last year, an epidemic of infantile urinary stone disease developed in China. Investigation revealed that melamine-tainted diary product caused urinary stone in these infants. Young infants were susceptible to the melamine toxicity and dehydration or other stone-prone factors aggravated the toxicity. Melamine-related urinary stones were small, multiple, and mainly composed of uric acid, thus conservative treatment of hydration and urine alkalinization worked well in majority of the patients.
참고문헌 (9)
- Zhang L, "Melamine-contaminated milk products induced urinary tract calculi in children", World J Pediatr, 5, pp.31~35 (2009)
- Lam CW, "Diagnosis and spectrum of melamine-related renal disease: plausible mechanism of stone formation in humans", Clin Chim Acta, 402, pp.150~155 (2009)
- Hau AK, "Melamine toxicity and the kidney", J Am Soc Nephrol, 20, pp.245~250 (2009)
- Guan N, "Melamine-contaminated powdered formula and urolithiasis in young children", N Engl J Med, 360, pp.1067~1074 (2009)
- Kyu-Shik Jeong, "Canine renal failure syndrome in three dogs", Journal of Veterinary Science, 7(3), pp.299~301 (2006), 대한수의학회
- Melnick RL, "Urolithiasis and bladder carcinogenicity of melamine in rodents", Toxicol Appl Pharmacol, 72, pp.292~303 (1984)
- Ogasawara H, "Urinary bladder carcinogenesis induced by melamine in F344 male rats: correlation between carcinogenicity and urolith formation", Carcinogenesis, 16, pp.2773~2777 (1995)
- Ding J, "Childhood urinary stones induced by melaminetainted formula: how much we know, how much we don't know", Kidney Int, 75, pp.780~782 (2009)
- Sun N, "Melamine related urinary calculus and acute renal failure in infants", Zhonghua Er Ke Za Zhi, 46, pp.810~815 (2008)