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요로결석의 성분분석: 최근 5년간 단일기관 분석 결과(2009년- 2013년)

Analysis of Urinary Stone Composition: A Retrospective Single Center Study during the Last Five Years (2009-2013)

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주제분류비뇨기과학

초록

Purpose: Analysis of urinary stone composition is essential for treatment and prevention of urolithiasis. We evaluated the effect of age, gender, and stone location on urinary stone components during the last five years.Materials and Methods: We conducted a retrospective analysis of the medical records of 375 patients ranging in age from 15 years old to 93 years old (241 males and 134 females) who underwent conventional or endoscopic surgery, shock wave lithotripsy, or passed their stones spontaneously between 2009 and 2013. Stone analysis was performed using a chemical analysis method to determine the molecular composition of each stone.Results: Of the 375 patients with urolithiasis, 152 patients (40.5%) had predomi-nantly calcium oxalate, 85 patients (21.5%) had uric acid, 17 patients (4.5%) had calcium phosphate, 17 patients (4.5%) had magnesium ammonium phosphate, 16 patients (4.3%) had calcium carbonate, and 86 patients (22.9%) had mixed stone type. There was a decreasing prevalence of calcium oxalate stone with age group (42.5% in young adult (20-39 years, n=40), 45.0% in adult (40-60 years, n=151), and 32.7% in elderly (≥60 years, n=180) as opposed to increasing prevalence in uric acid stone (7.5% in young adult, 15.2% in adult and 32.2% in elderly). Uric acid stones were more common in males and in lower urinary tract stones. Conclusions: In this study, the incidence of calcium oxalate decreased with age and that of uric acid increased with age and in male. In comparison of the results of previous studies for several decades, the incidence of uric acid increased in the last five years.

Abstract

Purpose: Analysis of urinary stone composition is essential for treatment and prevention of urolithiasis. We evaluated the effect of age, gender, and stone location on urinary stone components during the last five years.Materials and Methods: We conducted a retrospective analysis of the medical records of 375 patients ranging in age from 15 years old to 93 years old (241 males and 134 females) who underwent conventional or endoscopic surgery, shock wave lithotripsy, or passed their stones spontaneously between 2009 and 2013. Stone analysis was performed using a chemical analysis method to determine the molecular composition of each stone.Results: Of the 375 patients with urolithiasis, 152 patients (40.5%) had predomi-nantly calcium oxalate, 85 patients (21.5%) had uric acid, 17 patients (4.5%) had calcium phosphate, 17 patients (4.5%) had magnesium ammonium phosphate, 16 patients (4.3%) had calcium carbonate, and 86 patients (22.9%) had mixed stone type. There was a decreasing prevalence of calcium oxalate stone with age group (42.5% in young adult (20-39 years, n=40), 45.0% in adult (40-60 years, n=151), and 32.7% in elderly (≥60 years, n=180) as opposed to increasing prevalence in uric acid stone (7.5% in young adult, 15.2% in adult and 32.2% in elderly). Uric acid stones were more common in males and in lower urinary tract stones. Conclusions: In this study, the incidence of calcium oxalate decreased with age and that of uric acid increased with age and in male. In comparison of the results of previous studies for several decades, the incidence of uric acid increased in the last five years.

참고문헌 (24)

  1. Saita A, "Stone composition: where do we stand?", Urol Int, 79(Suppl 1), pp.16~19 (2007)
  2. Kim Hh, "Prevalence and epidemiologic characteristics of urolithiasis in Seoul, Korea", Urology, 59, pp.517~521 (2002)
  3. Johnson CM, "Renal stone epidemiology : a 25-year study in Rochester, Minnesota", Kidney Int, 16, pp.624~631 (1979)
  4. Smith LH, "The medical aspects of urolithiasis : an overview", J Urol, 141, pp.707~710 (1989)
  5. Akram Alaya, "Changes in Urinary Stone Composition in the Tunisian Population: A Retrospective Study of 1,301 Cases", Annals of Laboratory Medicine, 32(3), pp.177~183 (2012), 대한진단검사의학회
  6. Goldfarb DS, "Prevention of recurrent nephrolithiasis", Am Fam Physician, 60, pp.2269~2276 (1999)
  7. Kourambas J, "Role of stone analysis in metabolic evaluation and medical treatment of nephrolithiasis", J Endourol, 15, pp.181~186 (2001)
  8. Basiri A, "What is the state of the stone analysis techniques in urolithiasis?", Urol J, 9, pp.445~454 (2012)
  9. Asper R, "Epidemiology and socioeconomic aspects of urolithiasis", Urol Res, 12, pp.1~5 (1984)
  10. Hesse A, "Current aspects of epidemiology and nutrition in urinary stone disease", World J Urol, 15, pp.165~171 (1997)
  11. Daudon M, "Sex-and age-related composition of 10 617calculi analyzed by infrared spectroscopy", Urol Res, 23, pp.319~326 (1995)
  12. Byeon SS, "Analysis of the urinary stone components using chemical analysis method", Korean J Urol, 37, pp.179~186 (1996)
  13. 예석준, "요로결석의 성분분석: 20년간의 변화", Investigative and Clinical Urology, 48(12), pp.1285~1288 (2007), 대한비뇨기과학회
  14. Balaji KC, "Mechanism of stone formation", Urol Clin North Am, 24, pp.1~11 (1997)
  15. Menon M, "Oxalate metabolism and renal calculi", J Urol, 127, pp.148~151 (1982)
  16. Finlayson B, "Symposium on renal lithiasis. Renal lithiasis in review", Urol Clin North Am, 1, pp.181~212 (1974)
  17. Siener R, "The role of overweight and obesity in calcium oxalate stone formation", Obes Res, 12, pp.106~113 (2004)
  18. Coe FL, "Kidney stone disease", J Clin Invest, 115, pp.2598~2608 (2005)
  19. Abate N, "The metabolic syndrome and uric acid nephrolithiasis : novel features of renal manifestation of insulin resistance", Kidney Int, 65, pp.386~392 (2004)
  20. Maalouf NM, "Association of urinary pH with body weight in nephrolithiasis", Kidney Int, 65, pp.1422~1425 (2004)
  21. Negri AL, "Clinical and biochemical profile of patients with"pure"uric acid nephrolithiasis compared with"pure"calcium oxalate stone formers", Urol Res, 35, pp.247~251 (2007)
  22. Zechner O, "Idiopathic uric acid lithiasis : epidemiologic and metabolic aspects", J Urol, 128, pp.1219~1223 (1982)
  23. Poletto J, "Hyperuricemia and associated factors : a cross-sectional study of Japanese-Brazilians", Cad Saude Publica, 27, pp.369~378 (2011)
  24. Childs MA, "Pathogenesis of bladder calculi in the presence of urinary stasis", J Urol, 189, pp.1347~1351 (2013)

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