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BK polyomavirus-associated nephropathy

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주제분류소아과학

초록

BK polyomavirus (BKPyV) is a ubiquitous virus residing in the kidney tubules and is clinically significant only in immunocompromised patients. In clinical practice, BKPyV is a causative pathogen of BKPyV associated nephropathy (BKVAN) in kidney allograft recipients or hemorrhagic cystitis of hematopoietic stem cell transplant recipients. Currently, there is no effective treatment for BKVAN; therefore, careful monitoring and prudent modification of immunosuppression are necessary to prevent BKVAN. In this article, the epidemiology, pathophysiology, and current management strategies for BKVAN are reviewed.

Abstract

BK polyomavirus (BKPyV) is a ubiquitous virus residing in the kidney tubules and is clinically significant only in immunocompromised patients. In clinical practice, BKPyV is a causative pathogen of BKPyV associated nephropathy (BKVAN) in kidney allograft recipients or hemorrhagic cystitis of hematopoietic stem cell transplant recipients. Currently, there is no effective treatment for BKVAN; therefore, careful monitoring and prudent modification of immunosuppression are necessary to prevent BKVAN. In this article, the epidemiology, pathophysiology, and current management strategies for BKVAN are reviewed.

참고문헌 (35)

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관련 논문AI추천

Comparison of Detecting Methods of BK Virus Infection in Patients with Renal Allograft Recipients강창석, 김용수, 문인성, 박연준, 양철우, 이성학, 최영진대한병리학회 · Journal of Pathology and Translational Medicine2010 · 제44권 제6호Risk factors in the progression of BK virus-associated nephropathy in renal transplant recipients강은진, 김용수, 박철휘, 양철우, 이동재, 이혜민, 장인애, 정병하, 최범순, 최영진대한내과학회 · The Korean Journal of Internal Medicine2015 · 제30권 제6호Polyomavirus(BK Virus) Nephropathy in Kidney Transplant Patients: A Pathologic PerspectiveAmr S. Khaled연세대학교의과대학 · Yonsei Medical Journal2004 · 제45권 제6호Treatment of BK virus-associated hemorrhagic cystitis with low-dose intravenous cidofovir in patients undergoing allogeneic hematopoietic cell transplantation강승지, 김여경, 김재용, 김형준, 안서연, 안재숙, 양덕환, 이승신, 이제중, 장희창, 정미옥, 정성훈대한내과학회 · The Korean Journal of Internal Medicine2015 · 제30권 제2호Urinary Decoy Cell Grading and Its Clinical Implications고명주, 김연희, 노송미, 임범진, 정현주대한병리학회 · Journal of Pathology and Translational Medicine2012 · 제46권 제3호Usefulness of BK virus-specific interferon-γ enzyme-linked immunospot assay for predicting the outcome of BK virus infection in kidney transplant recipientsByung Ha Chung, Chul Woo Yang, Do Hyun Na, Eun-Jee Oh, Eun Jeong Ko, Hyeyoung Lee, Hyunjoo Bae, Ji Won Min, Ji-Yeun Chang, Ki Hyun Park대한내과학회 · The Korean Journal of Internal Medicine2021 · 제36권 제1호

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