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복합운동이 유방암 환자의 건강관련 체력과 혈중 렙틴 및 인슐린 농도의 변화에 미치는 영향

The Effects of combined exercise training for breast cancer survivors in Health related fitness, Leptin and Insulin

이난희|김수미|이청무|나선영
한국운동생리학회|2009.05|운동과학 (Exercise Science)|제18권 제2호|pp. 225-238|DOI 10.15857/ksep.2009.18.2.225

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참고문헌

키워드

유방암breast cancer렙틴leptin건강관련 체력복합운동Combined exerciseinsulin인슐린health related fitness

초록

본 연구는 복합운동이 유방암 환자들의 건강관련 체력과 렙틴 및 인슐린 농도의 변화에 미치는 영향을 분석하여 이들의 비만 예방과 개선 및 암 재발을 방지하고 나아가서는 건강한 삶을 영위하기 위한 운동 프로그램의 기초 자료를 제공하는데 그 목적이 있다. 총 20명의 유방암 환자(운동군: 10명, 통제군: 10명)를 대상으로 운동군의 경우 12주간 율동을 가미한 유산소운동과 탄력밴드를 이용한 근력운동으로 구성된 복합운동을 주 3회 실시하였으며 통제군은 12주간 일상생활을 유지하도록 하였다. 12주 운동 전 후의 차이를 분석한 결과 운동군의 경우 제지방량(p<.05), 심폐지구력(p<.01), 유연성(p<.05), 근지구력(p<.01)이 유의하게 증가하였고, 렙틴(p<.001)과 인슐린(p<.05) 농도가 유의하게 감소하였으나 통제군은 유의한 차이가 나타나지 않았다. 그리고 운동군과 통제군간의 집단간 차이를 검정한 결과 심폐지구력(p<.05), 유연성(p<.001), 근지구력(p<.001), 렙틴(p<.01) 그리고 인슐린(p<.05)의 농도에 있어서 유의한 차이가 나타났다. 따라서 본 연구에서 실시한 12주간의 복합운동은 유방암 환자의 건강관련 체력과 렙틴 및 인슐린 농도의 변화에 긍정적인 영향을 미쳐 유방암 환자에게 비만 예방과 개선 및 암의 재발을 방지하고 나아가 이들의 건강 유지·증진 및 삶의 질 향상을 위한 운동 프로그램의 기초자료로 유용하게 사용될 수 있을 것이라 사료된다.

Abstract

The Effects of combined exercise training for breast cancer survivors in Health related fitness, Leptin and Insulin. The purpose of this study was examine the effects of combined exercise training on health related fitness, leptin and insulin concentrations in breast cancer patients. Twenty sedentary, breast cancer survivors were randomly assigned either to a 12-week cardiovascular and elastic band strength training exercise intervention(3days/week) or to a usual care control group. Fasting leptin and insulin levels, body composition, harvard step, sit and reach, grip strength and sit up were collected at baseline and 12 weeks. The exercise group experienced significant increases in LBM(p<.05), cardiorespiratory endurance(p<.01), flexibility(p<.05) and muscle endurance(p<.01), but no significant changes in the control group. There was significant differences between groups in cardiorespiratory endurance(p<.05), flexibility(p<.001), and muscle endurance(p<.001). Fasting leptin concentrations decreased in the exercise group(p<.01), with no significant change in the control group and the comparison reached statistical significance(p<.01) between groups. Insulin concentrations decreased in the exercise group(p<.05), with no significant change in the control group and the comparison reached statistical significance(p<.05) between groups. Participation in an exercise intervention was associated with a significant decrease in leptin and insulin levels and increase in health related fitness in breast cancer survivors. The cardiovascular and elastic band exercise program for breast cancer survivors may be mediated, in part, through changes in leptin and insulin levels and/or changes in body fat or fat deposition.

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