Cardiac-specific overexpression of Ndufs1 ameliorates cardiac dysfunction after myocardial infarction by alleviating mitochondrial dysfunction and apoptosis

참고문헌 (48)

1. Roth, G. A., "Global burden of cardiovascular diseases and risk factors, 1990–2019", J. Am. Coll. Cardiol, 76, pp.2982~3021 (2020)
2. Chang, P. P., "Trends in hospitalizations and survival of acute decompensated heart failure in four US communities(2005–2014)", Circulation, 138, pp.12~24 (2018)
3. Mamas, M. A., "Do patients have worse outcomes in heart failure than in cancer? A primary care-based cohort study with 10-year follow-up in Scotland", Eur. J. Heart Fail, 19, pp.1095~1104 (2017)
4. Roger, V. L., "Epidemiology of heart failure", Circ. Res, 113, pp.646~659 (2013)
5. Anderson, J. L., "Acute myocardial infarction", N. Engl. J. Med, 376, pp.2053~2064 (2017)
6. Del Re, D. P., "Fundamental mechanisms of regulated cell death and implications for heart disease", Physiol. Rev, 99, pp.1765~1817 (2019)
7. Frangogiannis, N. G., "Cardiac fibrosis : cell biological mechanisms, molecular pathways and therapeutic opportunities", Mol. Asp. Med, 65, pp.70~99 (2019)
8. Hadas, Y., "Altering sphingolipid metabolism attenuates cell death and inflammatory response after myocardial infarction", Circulation, 141, pp.916~930 (2020)
9. Gerber, Y., "Mortality associated with heart failure after myocardial infarction", Circ. Heart Fail, 9, pp.e002460~ (2016)
10. O Gara, P. T., "2013 ACCF", AHA guideline for the management of ST-elevation myocardial infarction, 2013, pp.127, e362~e425
11. Yeh, R. W., "Population trends in the incidence and outcomes of acute myocardial infarction", N. Engl. J. Med, 362, pp.2155~2165 (2010)
12. Ni, Y., "Mutations in NDUFS1 cause metabolic reprogramming and disruption of the electron transfer", Cells, 8, pp.1149~ (2019)
13. Carroll, J., "Bovine complex I is a complex of 45 different subunits", J. Biol. Chem, 281, pp.32724~32727 (2006)
14. Letts, J. A., "Purification of ovine respiratory complex I results in a highly active and stable preparation", J. Biol. Chem, 291, pp.24657~24675 (2016)
15. Hirst, J., "The nuclear encoded subunits of complex I from bovine heart mitochondria", Biochim. Biophys. Acta, 1604, pp.135~150 (2003)
16. Zhu, J., "Structure of mammalian respiratory complex I", Nature, 536, pp.354~358 (2016)
17. Sharanek, A., "OSMR controls glioma stem cell respiration and confers resistance of glioblastoma to ionizing radiation", Nat. Commun, 11, pp.4116~ (2020)
18. Dunham-Snary, K. J., "Ndufs2, a core subunit of mitochondrial complex I, is essential for acute oxygen-sensing and hypoxic pulmonary vasoconstriction", Circ. Res, 124, pp.1727~1746 (2019)
19. Lopez-Fabuel, I., "Complex I assembly into supercomplexes determines differential mitochondrial ROS production in neurons and astrocytes", Proc. Natl Acad. Sci. USA, 113, pp.13063~13068 (2016)
20. Ni, Y., "Mutations in NDUFS1 cause metabolic reprogramming and disruption of the electron transfer", Cells, 8, pp.1149~ (2019)
21. Kussmaul, L., "The mechanism of superoxide production by NADH:ubiquinone oxidoreductase (complex I) from bovine heart mitochondria", Proc. Natl Acad. Sci. USA, 103, pp.7607~7612 (2006)
22. Elkholi, R., "MDM2 integrates cellular respiration and apoptotic signaling through NDUFS1 and the mitochondrial network", Mol. Cell, 74, pp.452~465 (2019)
23. Gao, E., "A novel and efficient model of coronary artery ligation and myocardial infarction in the mouse", Circ. Res, 107, pp.1445~1453 (2010)
24. Claycomb, W. C., "HL-1 cells: a cardiac muscle cell line that contracts and retains phenotypic characteristics of the adult cardiomyocyte", Proc. Natl Acad. Sci. USA, 95, pp.2979~2984 (1998)
25. Rath, S., "MitoCarta3.0: an updated mitochondrial proteome now with suborganelle localization and pathway annotations", Nucleic Acids Res, 49, pp.D1541~D1547 (2021)
26. Hu, L., "Targeting mitochondrial dynamics by regulating Mfn2 for therapeutic intervention in diabetic cardiomyopathy", Theranostics, 9, pp.3687~3706 (2019)
27. Qi, B., "Akap1 deficiency exacerbates diabetic cardiomyopathy in mice by NDUFS1-mediated mitochondrial dysfunction and apoptosis", Diabetologia, 63, pp.1072~1087 (2020)
28. Jenča, D., "Heart failure after myocardial infarction : incidence and predictors", ESC Heart Fail, 8, pp.222~237 (2021)
29. Perez-Gomez, R., "Downregulation of respiratory complex I mediates major signalling changes triggered by TOR activation", Sci. Rep, 10, pp.4401~ (2020)
30. Iannetti, E. F., "Rescue from galactose-induced death of Leigh Syndrome patient cells by pyruvate and NAD", Cell Death Dis, 9, pp.1135~ (2018)
31. Jiang, L., "Proteomic analysis reveals ginsenoside Rb1 attenuates myocardial ischemia", reperfusion injury through inhibiting ROS production from mitochondrial complex I, 2021, pp.11, 1703~1720
32. Iuso, A., "Dysfunctions of cellular oxidative metabolism in patients with mutations in the NDUFS1 and NDUFS4 genes of complex I", J. Biol. Chem, 281, pp.10374~10380 (2006)
33. Bandara, A. B., "Complex I protein NDUFS2 is vital for growth, ROS generation, membrane integrity, apoptosis, and mitochondrial energetics", Mitochondrion, 58, pp.160~168 (2021)
34. González-Rodríguez, P., "Disruption of mitochondrial complex I induces progressive parkinsonism", Nature, 599, pp.650~656 (2021)
35. Zou, R., "Ndufs1 deficiency aggravates the mitochondrial membrane potential dysfunction in pressure overload-induced myocardial hypertrophy", Oxid. Med. Cell. Longev, 2021, pp.1~21 (2021)
36. Srinivas, U. S., "ROS and the DNA damage response in cancer", Redox Biol, 25, pp.101084~ (2019)
37. Zhuang, C., "Oxidative stress induces chondrocyte apoptosis through caspase-dependent and caspase-independent mitochondrial pathways and the antioxidant mechanism of Angelica sinensis polysaccharide", Oxid. Med. Cell. Longev, 2020, pp.3240820~ (2020)
38. Xu, Y., "Sp1 targeted PARP1 inhibition protects cardiomyocytes from myocardial ischemia–reperfusion injury via downregulation of autophagy", Front. Cell Dev. Biol, 9, pp.621906~ (2021)
39. Ravi, V., "SIRT6 transcriptionally regulates global protein synthesis through transcription factor Sp1 independent of its deacetylase activity", Nucleic Acids Res, 47, pp.9115~9131 (2019)
40. Liu, B., "MiR-29b", Sp1, β-catenin pathway in acute myeloid leukemia, pp.J. Exp. Clin. Cancer Res, 2019[DOI]
41. Hu, Y., "Luteolin modulates SERCA2a via Sp1 upregulation to attenuate myocardial ischemia", reperfusion injury in mice, 2020, pp.10, 15407~
42. Tsuda, M., "Protein acetylation in skeletal muscle mitochondria is involved in impaired fatty acid oxidation and exercise intolerance in heart failure", J. Cachexia Sarcopenia Muscle, 9, pp.844~859 (2018)
43. Hoefs, S. J. G., "Novel mutations in the NDUFS1 gene cause low residual activities in human complex I deficiencies", Mol. Genet. Metab, 100, pp.251~256 (2010)
44. Naso, M. F., "Adeno-associated virus(AAV)as a vector for gene therapy", Biodrugs, 31, pp.317~334 (2017)
45. Leborgne, C., "IgG-cleaving endopeptidase enables in vivo gene therapy in the presence of anti-AAV neutralizing antibodies", Nat. Med, 26, pp.1096~1101 (2020)
46. Russell, S., "Efficacy and safety of voretigene neparvovec(AAV2-hRPE65v2)in patients with RPE65-mediated inherited retinal dystrophy : a randomised, controlled, open-label, phase 3 trial", Lancet, 390, pp.849~860 (2017)
47. Wang, D., "Adeno-associated virus vector as a platform for gene therapy delivery", Nat. Rev. Drug Discov, 18, pp.358~378 (2019)
48. Nidetz, N. F., "Adeno-associated viral vector-mediated immune responses:understanding barriers to gene delivery", Pharmacol. Ther, 207, pp.107453~ (2020)

관련 논문AI추천