서울시 미세먼지(PM10)와 초미세먼지(PM2.5)의 단기노출로 인한 사망영향
Effects of Short-term Exposure to PM10 and PM2.5 on Mortality in Seoul
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초록
Objectives: Although a number of epidemiologic studies have examined the association between air pollution and mortality, data limitations have resulted in fewer studies of particulate matter with an aerodynamic diameter of ≤2.5 μm (PM2.5). We conducted a time-series study of the acute effects of particulate matter with an aerodynamic diameter of ≤10 μm(PM10) and PM2.5 on the increased risk of death for all causes andcardiovascular mortality in Seoul, Korea from 2006 to 2010. Methods: We applied the generalized additive model (GAM) with penalized splines, adjusting for time, day of week, holiday, temperature, and relative humidity in order to investigate the association between risk of mortality and particulate matter. Results: We found that PM10 and PM2.5 were associated with an increased risk of mortality for all causes and of cardiovascular mortality in Seoul. A 10 μg/m3 increase in the concentration of PM10 corresponded to 0.44%(95% Confidence Interval [CI]: 0.25-0.63%), and 0.95% (95% CI: 0.16-1.73%) increase of all causes and of cardiovascular mortality. A 10 μg/m3 increase in the concentration of PM2.5 corresponded to 0.76% (95% CI:0.40-1.12%), and 1.63% (95% CI: 0.89-2.37%) increase of all causes and cardiovascular mortality. Conclusion: We conclude that PM10 and PM2.5 have an adverse effect on population health and that this strengthens the rationale for further limiting levels of PM10 and PM2.5 in Seoul.
Abstract
Objectives: Although a number of epidemiologic studies have examined the association between air pollution and mortality, data limitations have resulted in fewer studies of particulate matter with an aerodynamic diameter of ≤2.5 μm (PM2.5). We conducted a time-series study of the acute effects of particulate matter with an aerodynamic diameter of ≤10 μm(PM10) and PM2.5 on the increased risk of death for all causes andcardiovascular mortality in Seoul, Korea from 2006 to 2010. Methods: We applied the generalized additive model (GAM) with penalized splines, adjusting for time, day of week, holiday, temperature, and relative humidity in order to investigate the association between risk of mortality and particulate matter. Results: We found that PM10 and PM2.5 were associated with an increased risk of mortality for all causes and of cardiovascular mortality in Seoul. A 10 μg/m3 increase in the concentration of PM10 corresponded to 0.44%(95% Confidence Interval [CI]: 0.25-0.63%), and 0.95% (95% CI: 0.16-1.73%) increase of all causes and of cardiovascular mortality. A 10 μg/m3 increase in the concentration of PM2.5 corresponded to 0.76% (95% CI:0.40-1.12%), and 1.63% (95% CI: 0.89-2.37%) increase of all causes and cardiovascular mortality. Conclusion: We conclude that PM10 and PM2.5 have an adverse effect on population health and that this strengthens the rationale for further limiting levels of PM10 and PM2.5 in Seoul.
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