The Effect of Cichorium intybus Extract on Hepatotoxicity in Rats
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Abstract
Cichorium intybus (Compositae) has been used for fevers, dyspepsia, headache and jaundice, as a demulcent. Also, it has relaxation effects and relief effects against coffee and teas, and is widely used as food. We investigated anti-lipid peroxidative effects and liver protective activity on CCl4 induced lipid peroxidation and hepatotoxicity in rats. MeOH Ex. enhanced the inhibition of anti-lipid peroxidative effects in liver lipid. In chemical parameters obtained from serum analysis, MeOH Ex. revealed significant decrease on hepatotoxicity. The results were as follows; 1. The inhibitory effects of lipid peroxidation were shown in accordance with the increase of samples concentration level.2. In chemical parameters obtained from serum analysis, the activities of GOT, GPT, AlP were restored to near the normal level. The contents of cholesterol and BUN showed inhibitory effects with valence. 3. The weights of liver and spleen were not able to restore to the normal level. But on a general level, they were reduced more than the control group.
참고문헌 (18)
- "The Standard Cyclopedia of Horticulture" (1942), Macmillan Company
- "Indigenous Drugs of India" (1958)
- "A Manual Flora of Egypt", 2, pp.1045~ (1912)
- "In Technology of Concentrated Foods" (1970)
- "Lactucin und Lactucopikrin" (1953)
- "Biosynthesis of 6 7-dihydroxycoumarin in Cichorium intybus" (1983)
- "Rosten und Rostwaren", ing neue bearbeitung (1934)
- "A simple fluormetric assay for lipid peroxide in blood plasma" (1976)
- "The effects of chelidonii herba extract on the cell mediate and humoral immune responses in mice", 31(1), pp.66~ (2005)
- "Anti lipid peroxidation and liver protective effects of polygonum aviculare L" (1994)
- "Effects of Aralia elata on Lipid peroxidation", 37, pp.270~ (1993)
- "Handbook of Arabian medicinal Plants" (1994), 42 CRC Press
- "Inhibitory Effect of Doen-jang (Korean Fermented Soybean Paste) and Soybean Extracts on the Growth of KB Cells", 31(5), pp.444~ (2005)
- "Comparision of Swiss red wheat grain and fractions for their antioxidantproperties", 52, pp.1118~ (2004)
- "Effect of foliar application of selenium on the antioxidant activity of aqueous and ethanolic extracts of selenium-enriched rice", 52, pp.1759~ (2004)
- "Antioxidant components of ardenia fruit" (1994)
- "Conjugated dienoic acid induces lipid peroxidation in humans", 468, pp.33~36 (2000)
- "Anti-microbial activity of soybean extract against oral microbes", 32(2), pp.192~ (2006)